GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to manZ

Finding the characterized proteins for manZ (glucose PTS, enzyme EIID) in trehalose catabolism

Or see clustering for step manZ

Or see all steps for trehalose catabolism

Or cluster curated proteins matching a keyword

Definition of manZ

Fetched 6 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 7 other characterized sequences. (Found 13 hits including self hits.)

Removing ignored items reduces this to 5 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for manZ.)

TC 4.A.6.1.16 / Q8Y8W1 Lmo0781 protein, component of Constitutively synthesized sensor, MpoABCD, controlling man operon (see TC# 4.A.6.1.15) expression by interacting with and phosphorylating ManR, the transcriptional regulator of the man operon from Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e)
PFams: EIID-AGA
Heteromeric, 292 amino acids: PaperBLAST, CDD, TCDB::Q8Y8W1
72% identical to

TC 4.A.6.1.1 / P69805 PTND aka MANZ aka PTSM aka GPTB aka B1819, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose from Escherichia coli
PFams: EIID-AGA
Heteromeric, 286 amino acids: PaperBLAST, CDD

PTRD_KLEPN / P37083 PTS system sorbose-specific EIID component; EIID-Sor; Sorbose permease IID component from Klebsiella pneumoniae
TC 4.A.6.1.3 / P37083 PTRD aka SORM, component of Sorbose porter from Klebsiella pneumoniae
PFams: EIID-AGA
Heteromeric, 274 amino acids: PaperBLAST, CDD, SwissProt::P37083
61% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

TC 4.A.6.1.2 / P26382 PTFD aka LEVG, component of Fructose group translocator, LevDEFG from Bacillus subtilis
PFams: EIID-AGA
Heteromeric, 275 amino acids: PaperBLAST, CDD, TCDB::P26382
60% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

PTRD_LACCA / Q9RGG2 PTS system sorbose-specific EIID component; EIID-Sor; Sorbose permease IID component from Lactobacillus casei
Q9RGG2 protein-Npi-phosphohistidine-L-sorbose phosphotransferase (subunit 1/4) (EC 2.7.1.206) from Lactobacillus casei
PFams: EIID-AGA
Heteromeric, 282 amino acids: PaperBLAST, CDD, SwissProt::Q9RGG2
56% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

A0A0F6BB80 fructoselysine/glucoselysine PTS enzyme IID component from Salmonella typhimurium (strain 14028s / SGSC 2262)
TC 4.A.6.1.19 / V7RGM6 PTS mannose transporter subunit IID, component of PTS uptake system for glucoselysine and fructoselysine, GfrABCD from Salmonella enterica subsp. enterica serovar Give var. 15 str. CFSAN004343
PFams: EIID-AGA
Heteromeric, 278 amino acids: PaperBLAST, CDD, TCDB::V7RGM6
40% identical to

b1819 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
P69805 mannose-specific PTS enzyme IID component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PTND_ECOLI / P69805 PTS system mannose-specific EIID component; EII-M-Man; EIID-Man; Mannose permease IID component from Escherichia coli (strain K12)
PFams: EIID-AGA
Heteromeric, 283 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for manZ.)

Q5IRC0 protein-Npi-phosphohistidine-D-mannose phosphotransferase (EC 2.7.1.191) from Streptococcus suis
PFams: EIID-AGA
303 amino acids: PaperBLAST, CDD, BRENDA::Q5IRC0
80% identical to

TC 4.A.6.1.7 / Q5M5W8 ManN, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
PFams: EIID-AGA
Heteromeric, 303 amino acids: PaperBLAST, CDD

TC 4.A.6.1.11 / D2BKY9 Mannose-specific PTS system, IID component, component of Mannose enzyme II complex, IIAB, IIC, IID. IIC/IID serve allows entry of some bacteriocins including pediocin (class IIa) and lactococcin A (class IIc) (Kjos et al., 2011). Transports and phosphorylates Glucose, Mannose and Glucosamine from Lactococcus lactis subsp. lactis (strain KF147)
PFams: EIID-AGA
Heteromeric, 307 amino acids: PaperBLAST, CDD, TCDB::D2BKY9
67% identical to

TC 4.A.6.1.7 / Q5M5W8 ManN, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
PFams: EIID-AGA
Heteromeric, 303 amino acids: PaperBLAST, CDD