Sequence Cluster id id2 desc organism isHeteromeric 1 Cluster1 BRENDA::A6MIZ4 alpha,alpha-trehalase (EC 3.2.1.28) Physcomitrella patens 2 Cluster1 BRENDA::A4WBE4 alpha,alpha-trehalase (EC 3.2.1.28) Enterobacter sp. 3 Cluster1 BRENDA::B0CV22 alpha,alpha-trehalase (EC 3.2.1.28) Laccaria bicolor 4 Cluster1 BRENDA::C0LZJ7 alpha,alpha-trehalase (EC 3.2.1.28) Nilaparvata lugens 5 Cluster1 BRENDA::D2KHI9 alpha,alpha-trehalase (EC 3.2.1.28) Spodoptera litura 6 Cluster1 BRENDA::D2KHJ0 alpha,alpha-trehalase (EC 3.2.1.28) Spodoptera litura 7 Cluster1 BRENDA::D2KWM9 alpha,alpha-trehalase (EC 3.2.1.28) Nicotiana tabacum 8 Cluster1 BRENDA::D4I261 alpha,alpha-trehalase (EC 3.2.1.28) Erwinia amylovora 9 Cluster1 BRENDA::P13482 alpha,alpha-trehalase (EC 3.2.1.28) Escherichia coli 9 Cluster1 CAZy::AAC74281.1 α,α-trehalase (periplasmic) (TreA;OsmA) (Tre37A) (EC 3.2.1.28) 9 Cluster1 SwissProt::P13482 TREA_ECOLI Periplasmic trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; Tre37A; EC 3.2.1.28 Escherichia coli (strain K12) 9 Cluster1 ecocyc::TREHALAPERI-MONOMER b1197 periplasmic trehalase (EC 3.2.1.28) Escherichia coli K-12 substr. MG1655 9 Cluster1 metacyc::TREHALAPERI-MONOMER P13482 periplasmic trehalase (EC 3.2.1.28) Escherichia coli (strain K12) 10 Cluster1 BRENDA::P32359 alpha,alpha-trehalase (EC 3.2.1.28) Tenebrio molitor 10 Cluster1 CAZy::BAA01951.1 trehalase (EC 3.2.1.28) 11 Cluster1 BRENDA::Q3BXX2 alpha,alpha-trehalase (EC 3.2.1.28) Xanthomonas campestris 12 Cluster1 BRENDA::Q9GYK9 alpha,alpha-trehalase (EC 3.2.1.28) Caenorhabditis elegans 13 Cluster1 BRENDA::Q9JLT2 alpha,alpha-trehalase (EC 3.2.1.28) Mus musculus 13 Cluster1 CAZy::AAF61430.1 trehalase (EC 3.2.1.28) 14 Cluster1 BRENDA::Q9SU50 alpha,alpha-trehalase (EC 3.2.1.28) Arabidopsis thaliana 14 Cluster1 CAZy::CAB51647.1 trehalase (AtTre1;At4g24040/T19F6.30) (plasma membrane-bound) (EC 3.2.1.28) 14 Cluster1 SwissProt::Q9SU50 TRE1_ARATH Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; Trehalase 1; AtTRE1; EC 3.2.1.28 Arabidopsis thaliana (Mouse-ear cress) 15 Cluster1 BRENDA::Q9W2M2 alpha,alpha-trehalase (EC 3.2.1.28) Drosophila melanogaster 16 Cluster1 CAZy::AAC76544.1 trehalase (TreF;b3519) (EC 3.2.1.28) 16 Cluster1 SwissProt::P62601 TREF_ECOLI Cytoplasmic trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Escherichia coli (strain K12) 16 Cluster1 ecocyc::TREHALACYTO-MONOMER b3519 cytoplasmic trehalase (EC 3.2.1.28) Escherichia coli K-12 substr. MG1655 16 Cluster1 metacyc::TREHALACYTO-MONOMER P62601 cytoplasmic trehalase (EC 3.2.1.28) Escherichia coli (strain K12) 17 Cluster1 CAZy::AAD22970.1 trehalase 1 (Tre1) (EC 3.2.1.28) 17 Cluster1 BRENDA::Q9XEY7 alpha,alpha-trehalase (EC 3.2.1.28) Glycine max 18 Cluster1 CAZy::ABC59065.1 trehalase (TreA;Rmar_0119) (periplasmic) (EC 3.2.1.28) 18 Cluster1 BRENDA::A1XBT9 alpha,alpha-trehalase (EC 3.2.1.28) Rhodothermus marinus 19 Cluster1 CAZy::ABE27189.1 trehalase (SfTre1) (soluble; midgut) (EC 3.2.1.28) 19 Cluster1 BRENDA::Q0ZIF5 alpha,alpha-trehalase (EC 3.2.1.28) Spodoptera frugiperda 20 Cluster1 CAZy::ABO20846.1 trehalase 1 (Treh-1) (EC 3.2.1.28) 21 Cluster1 CAZy::ABU95354.1 trehalase 2 (Tre-2;Treh-2;SeTre-2) (EC 3.2.1.28) 21 Cluster1 BRENDA::A7XZC0 alpha,alpha-trehalase (EC 3.2.1.28) Spodoptera exigua 22 Cluster1 CAZy::ABY86218.1 trehalase-1 (Tre-1;SeTre-1) (EC 3.2.1.28) 22 Cluster1 BRENDA::B0M0J3 alpha,alpha-trehalase (EC 3.2.1.28) Spodoptera exigua 23 Cluster1 CAZy::ACF94698.1 trehalase (SfTre2) (EC 3.2.1.28) 23 Cluster1 BRENDA::B5ATV4 alpha,alpha-trehalase (EC 3.2.1.28) Spodoptera frugiperda 24 Cluster1 CAZy::ACN85420.1 trehalase (Tre-1) (soluble) (EC 3.2.1.28) 24 Cluster1 BRENDA::C0LZJ6 alpha,alpha-trehalase (EC 3.2.1.28) Nilaparvata lugens 25 Cluster1 CAZy::ADT91708.1 trehalase (Tre-1) (EC 3.2.1.28) 25 Cluster1 BRENDA::J7EJ73 alpha,alpha-trehalase (EC 3.2.1.28) Chironomus riparius 26 Cluster1 CAZy::AGK89798.1 soluble trehalase (ALTre-1) (EC 3.2.1.28) 27 Cluster1 CAZy::AGL34007.2 membrane-bound trehalase (ALTre-2) (EC 3.2.1.28) 28 Cluster1 CAZy::AGO32658.1 trehalase (Tre1;TmTre1) (soluble; midgut) (EC 3.2.1.28) 29 Cluster1 CAZy::BAA02909.1 trehalase (Treh1) (EC 3.2.1.28) 29 Cluster1 BRENDA::P32358 alpha,alpha-trehalase (EC 3.2.1.28) Bombyx mori 30 Cluster1 CAZy::BAA24381.1 trehalase (TreA;TreH) (EC 3.2.1.28) 31 Cluster1 CAZy::BAE45249.1 trehalase 2 (Treh2;Treh-2) (EC 3.2.1.28) 31 Cluster1 BRENDA::Q3MV18 alpha,alpha-trehalase (EC 3.2.1.28) Bombyx mori 32 Cluster1 SwissProt::A8J4S9 TREA_APIME Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Apis mellifera (Honeybee) 32 Cluster1 BRENDA::A8J4S9 alpha,alpha-trehalase (EC 3.2.1.28) Apis mellifera 32 Cluster1 CAZy::BAF81545.1 α,α-trehalase (EC 3.2.1.28) 32 Cluster1 metacyc::MONOMER-17105 A8J4S9 trehalase (bound form) (EC 3.2.1.28) Apis mellifera 33 Cluster1 SwissProt::O43280 TREA_HUMAN Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Homo sapiens (Human) 33 Cluster1 BRENDA::O43280 alpha,alpha-trehalase (EC 3.2.1.28) Homo sapiens 34 Cluster1 SwissProt::P19813 TREA_RABIT Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Oryctolagus cuniculus (Rabbit) 34 Cluster1 CAZy::AAA63460.1 trehalase (TreH;TreA) (EC 3.2.1.28) 35 Cluster1 reanno::pseudo5_N2C3_1:AO356_24205 AO356_24205 Alpha,alpha-trehalase (EC 3.2.1.28) Pseudomonas fluorescens FW300-N2C3 36 Cluster2 BRENDA::A4QMP6 alpha,alpha-trehalase (EC 3.2.1.28) Rhizophagus intraradices 37 Cluster2 BRENDA::B0DA99 alpha,alpha-trehalase (EC 3.2.1.28) Laccaria bicolor 38 Cluster2 BRENDA::F8MBS5 alpha,alpha-trehalase (EC 3.2.1.28) Neurospora tetrasperma 39 Cluster2 BRENDA::O42777 alpha,alpha-trehalase (EC 3.2.1.28) Aspergillus nidulans 40 Cluster2 BRENDA::O42783 alpha,alpha-trehalase (EC 3.2.1.28) Neurospora crassa 41 Cluster2 CAZy::AAB88889.1 trehalase (EC 3.2.1.28) 42 Cluster2 CAZy::AAB99831.1 α,α-trehalase (TreB;AN5635.2) (EC 3.2.1.28) 42 Cluster2 CharProtDB::CH_122465 Neutral trehalase (alpha,alpha-trehalase)(alpha,alpha-trehalose glucohydrolase); EC 3.2.1.28 Emericella nidulans 43 Cluster2 CAZy::AAC01744.1 trehalase (TreB) (EC 3.2.1.28) 44 Cluster2 CAZy::AAN46743.1 neutral trehalase (NTH1) (EC 3.2.1.28) 44 Cluster2 CAZy::EAA53721.1 neutral trehalase (NTH1;MG09471.4) (EC 3.2.1.28) 44 Cluster2 CharProtDB::CH_124151 neutral trehalase Magnaporthe grisea 70-15 44 Cluster2 SwissProt::O42622 TREB_MAGO7 Neutral trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae) 45 Cluster2 CAZy::AAS67888.1 neutral trehalase (Ntl) (EC 3.2.1.28) 45 Cluster2 BRENDA::Q6Q5X7 alpha,alpha-trehalase (EC 3.2.1.28) Metarhizium acridum 46 Cluster2 CAZy::AAV19867.1 neutral trehalase 1 (Nth1;Nth;YDR001c;YD8119.07c) (EC 3.2.1.28) 46 Cluster2 SwissProt::P32356 TREA_YEAST Neutral trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 46 Cluster2 metacyc::YDR001C-MONOMER P32356 neutral trehalase subunit (EC 3.2.1.28) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 47 Cluster2 CAZy::AAW41560.1 neutral trehalase 1 (NTH1;CNB02790) (EC 3.2.1.28) 48 Cluster2 CAZy::ABM16911.1 neutral trehalase (Nth1;BbNTH1) (EC 3.2.1.28) 48 Cluster2 BRENDA::A1YQE2 alpha,alpha-trehalase (EC 3.2.1.28) Beauveria bassiana 49 Cluster2 CAZy::CAA11904.1 neutral trehalase (Ntp1;SPBC660.07) (EC 3.2.1.28) 49 Cluster2 CharProtDB::CH_124701 alpha,alpha-trehalase Ntp1; EC 3.2.1.28 Schizosaccharomyces pombe 49 Cluster2 SwissProt::O42893 TREA_SCHPO Neutral trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) 50 Cluster2 CAZy::CAA57181.1 neutral trehalase (Nth1) (EC 3.2.1.28) 50 Cluster2 CAZy::CAG99815.1 neutral trehalase (TreA;KLLA0E17325g) (EC 3.2.1.28) 51 Cluster2 CAZy::CAA64476.1 neutral trehalase (Ntc1;CaNTC1) (EC 3.2.1.28) 51 Cluster2 BRENDA::P52494 alpha,alpha-trehalase (EC 3.2.1.28) Candida albicans 52 Cluster2 CAZy::CAA81270.1 neutral trehalase 2 (Nth2;YBR001c;YBR0106) (EC 3.2.1.28) 52 Cluster2 SwissProt::P35172 TREB_YEAST Probable trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 52 Cluster2 metacyc::YBR001C-MONOMER P35172 cytosolic trehalase 2 (EC 3.2.1.28) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 53 Cluster2 CAZy::CAC17620.1 neutral trehalase (Nthi;Ntl1) (EC 3.2.1.28) 53 Cluster2 CAZy::AAT68667.1 neutral trehalase (NTL) (EC 3.2.1.28) 54 Cluster2 CAZy::CAK43979.1 trehalase B (TreB;An01g09290) (EC 3.2.1.28) 55 Cluster2 CAZy::DAA05786.1 neutral trehalase (Nth1;CNAG_03785) (EC 3.2.1.28) 56 Cluster3 CAZy::CCE43253.1 trehalase (Atc1;CpATC1;CPAR2_208980) (EC 3.2.1.28) 57 Cluster3 BRENDA::P48016 alpha,alpha-trehalase (EC 3.2.1.28) Saccharomyces cerevisiae 57 Cluster3 CAZy::CAA89280.1 acid trehalase (vacuolar) (Ath1;YPR026w;YP9367.06) (EC 3.2.1.28) 57 Cluster3 SwissProt::P48016 ATH1_YEAST Vacuolar acid trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 57 Cluster3 metacyc::YPR026W-MONOMER P48016 periplasmic/vacuolar trehalase (EC 3.2.1.28) Saccharomyces cerevisiae (strain ATCC 204508 / S288c) 58 Cluster3 CAZy::AAB57642.1 acid trehalase (TreA) (EC 3.2.1.28) 58 Cluster3 CharProtDB::CH_122144 alpha, alpha-trehalase; EC 3.2.1.28 Emericella nidulans 59 Cluster3 CAZy::AAV05390.1 acid trehalase (Atc1;CaATC1) (EC 3.2.1.28) 60 Cluster3 CAZy::ABO93464.1 acid trehalase (Atm1) (EC 3.2.1.28) 60 Cluster3 BRENDA::A9XE63 alpha,alpha-trehalase (EC 3.2.1.28) Metarhizium anisopliae 61 Cluster3 CAZy::AGG12634.1 acid trehalase (Ath1;CgATH1;CAGLOK05137g) (EC 3.2.1.28) 62 Cluster3 CAZy::EAA66407.1 AN9340.2 (TreA) (EC 3.2.1.28) 63 Cluster3 SwissProt::D4B5H9 ATC1_ARTBC Cell wall acid trehalase ARB_03719; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) 64 Cluster3 SwissProt::Q5AAU5 ATC1_CANAL Cell wall acid trehalase ATC1; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) 65 Cluster4 SwissProt::P71741 TREH_MYCTU Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) 66 Cluster4 CAZy::ABK72415.1 α,α-trehalase (MSMEG_4535;MSMEG4528) (EC 3.2.1.28) 66 Cluster4 SwissProt::A0R0W9 TREH_MYCS2 Trehalase; Alpha,alpha-trehalase; Alpha,alpha-trehalose glucohydrolase; EC 3.2.1.28 Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) 67 Cluster4 SwissProt::Q4J7W0 TREH1_SULAC Trehalase 1; Alpha,alpha-trehalase; SaTreH1; EC 3.2.1.28 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) 68 Cluster4 SwissProt::Q4J9D4 TREH2_SULAC Trehalase 2; Alpha,alpha-trehalase; SaTreH2; EC 3.2.1.28 Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) 69 Cluster4 SwissProt::Q978S7 TREH_THEVO Trehalase; Alpha,alpha-trehalase; EC 3.2.1.28 Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1) 70 Cluster4 SwissProt::Q9HLE2 TREH_THEAC Trehalase; Alpha,alpha-trehalase; EC 3.2.1.28 Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165) 71 Cluster5 CAZy::AAS80455.1 α,α-trehalase / α-glucosidase (TTC0107) (EC 3.2.1.20|3.2.1.28) 72 Cluster5 UniProt::A8LLL3 Alpha-glucosidase; EC=3.2.1.- 73 Cluster5 UniProt::I7EUW4 Putative alpha-glucosidase AglA 74 Singleton1 CAZy::AAW44482.1 neutral trehalase 2 (NTH2;CNG00690) (EC 3.2.1.28) 75 Singleton2 CAZy::BAG85338.1 trehalase (TreH) (EC 3.2.1.28) 75 Singleton2 BRENDA::B6ZIV1 alpha,alpha-trehalase (EC 3.2.1.28) Nostoc punctiforme