Other Characterized Proteins Similar to aroP

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to aroP

Finding the characterized proteins for aroP (tryptophan:H+ symporter AroP) in L-tryptophan catabolism

Or see clustering for step aroP

Or see all steps for L-tryptophan catabolism

Or cluster curated proteins matching a keyword

Definition of aroP

Curated sequence P15993: Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan. aromatic amino acid:H⁺ symporter AroP. aromatic amino acid:H⁺ symporter AroP
Curated sequence F2HN33: Transporter for phenylalainine, tyrosine and tryptophan of 449 aas and 12 TMSs, FywP or YsjA
Curated sequence Q2VQZ4: Arbuscular mycorrhizal fungal proline:H+ symporter, AAP1 (binds and probably transports nonpolar, hydrophobic amino acids)
Curated sequence Q46065: Aromatic amino acid permease, AroP
UniProt sequence A0A0N9WG97: SubName: Full=Amino acid permease {ECO:0000313|EMBL:ALI00611.1};
UniProt sequence Q4KIP0: SubName: Full=Aromatic amino acid transport protein AroP {ECO:0000313|EMBL:AAY96158.1};
Ignore hits to A2RMP5 when looking for 'other' hits (Aromatic amino acid permease FywP)
Ignore hits to AO356_18530 when looking for 'other' hits (L-tyrosine transporter)
Comment: AO353_05930 (A0A0N9WG97) from Pseudomonas fluorescens FW300-N2E3 is related to aroP and is specifically improtant for tryptophan utilization (although more so if Trp is the nitrogen source). PfGW456L13_4291 (A0A293QSB2) from P. fluorescens GW4560-L13 is related to aroP and is specifically important for tryptophan utilization. Unfortunately A0A293QSB2 is no longer in UniProt; the closest remaining sequence is Q4KIP0 (only 87% identical). FywP (A2RMP5) may well be a tryptophan transporter as well, so ignore.

Fetched 6 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 38 other characterized sequences. (Found 42 hits including self hits.)

Removing ignored items reduces this to 36 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for aroP.)

b0576 phenylalanine:H⁺ symporter PheP from Escherichia coli K-12 substr. MG1655
P24207 phenylalanine:H⁺ symporter PheP from Escherichia coli (strain K12)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli
PFams: AA_permease, AA_permease_2
458 amino acids: PaperBLAST, CDD, TCDB::P24207
64% identical to

b0112 aromatic amino acid:H⁺ symporter AroP from Escherichia coli K-12 substr. MG1655
P15993 aromatic amino acid:H⁺ symporter AroP from Escherichia coli (strain K12)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli
PFams: AA_permease, AA_permease_2
457 amino acids: PaperBLAST, CDD

YI26_SCHPO / Q9P768 Uncharacterized amino-acid permease P7G5.06 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
CH_125860 plasma membrane amino acid permease Per1 from Schizosaccharomyces pombe
PFams: AA_permease, AA_permease_2
583 amino acids: PaperBLAST, CDD, CharProtDB::CH_125860
50% identical to

TC 2.A.3.10.22 / Q2VQZ4 Arbuscular mycorrhizal fungal proline:H+ symporter, AAP1 (binds and probably transports nonpolar, hydrophobic amino acids) from Glomus mosseae
PFams: AA_permease, AA_permease_2
536 amino acids: PaperBLAST, CDD

AAT1_SCHPO / Q9P5N2 Amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: AA_permease_2, AA_permease
579 amino acids: PaperBLAST, CDD, SwissProt::Q9P5N2
51% identical to

GAP2_CANAL / A0A1D8PK89 General amino-acid permease GAP2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
TC 2.A.3.10.24 / Q59YT0 General amino and permease and transceptor, GAP2. Transports all amino acids including citruline and eight tested toxic amino acid derivatives from Candida albicans
PFams: AA_permease, AA_permease_2
588 amino acids: PaperBLAST, CDD, SwissProt::A0A1D8PK89
52% identical to

GAP1_YEAST / P19145 General amino-acid permease GAP1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.2 / P19145 General amino acid permease (all L-amino acids and some D-amino acids as well as β-alanine, polyamines and GABA) from Saccharomyces cerevisiae (Baker's yeast)
RF|NP_012965.1 general amino-acid permease GAP1 from Saccharomyces cerevisiae
PFams: AA_permease, AA_permease_2
602 amino acids: PaperBLAST, CDD, CharProtDB::CH_091237
52% identical to

TC 2.A.3.10.21 / Q9URZ4 The basic amino acid (canavanine sensitivity) transporter, Cat1 from Schizosaccharomyces pombe (Fission yeast)
RF|NP_595008.2 uncharacterized amino-acid permease C869.11 from Schizosaccharomyces pombe
PFams: AA_permease, AA_permease_2
580 amino acids: PaperBLAST, CDD, CharProtDB::CH_091412
49% identical to

CAT1_SCHPO / Q9URZ4 Cationic amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: AA_permease, AA_permease_2
587 amino acids: PaperBLAST, CDD, SwissProt::Q9URZ4
49% identical to

TC 2.A.3.10.28 / O60170 Probable amino-acid permease Meu22 (Meiotic expression up-regulated protein 22) from Schizosaccharomyces pombe (strain 972 / ATCC 24843)
PFams: AA_permease, AA_permease_2
574 amino acids: PaperBLAST, CDD, TCDB::O60170
45% identical to

AO353_12275 histidine permease from Pseudomonas fluorescens FW300-N2E3
PFams: AA_permease, AA_permease_2
468 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_12275
45% identical to

GAP3_CANAL / A0A1D8PN88 Amino-acid permease GAP3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: AA_permease, AA_permease_2
599 amino acids: PaperBLAST, CDD, SwissProt::A0A1D8PN88
48% identical to

TC 2.A.3.10.26 / Q59NZ6 General amino acid porter, GAP6. Transports almost all amino acids tested except arginine and citruline from Candida albicans
PFams: AA_permease_2, AA_permease
576 amino acids: PaperBLAST, CDD, TCDB::Q59NZ6
48% identical to

GAP6_CANAL / A0A1D8PNP3 Amino-acid permease GAP6 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: AA_permease_2, AA_permease
568 amino acids: PaperBLAST, CDD, SwissProt::A0A1D8PNP3
48% identical to

AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
PFams: AA_permease, AA_permease_2
472 amino acids: PaperBLAST, CDD, reanno::pseudo3_N2E3:AO353_16120
44% identical to

Q4KIP0 Aromatic amino acid transport protein AroP
466 amino acids: PaperBLAST, CDD

PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
PFams: AA_permease, AA_permease_2
472 amino acids: PaperBLAST, CDD, reanno::WCS417:GFF1065
45% identical to

Q4KIP0 Aromatic amino acid transport protein AroP
466 amino acids: PaperBLAST, CDD

GAP1_CANAL / Q5AG77 Amino-acid permease GAP1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
TC 2.A.3.10.23 / Q5AG77 Amino acid permease, GAP1. Transports Arg, Met, Leu and Phe from Candida albicans
CH_123668 general amino acid permease from Candida albicans
PFams: AA_permease_2, AA_permease
582 amino acids: PaperBLAST, CDD, SwissProt::Q5AG77
47% identical to

RF|NP_595000.1 amino acid permease Isp5 from Schizosaccharomyces pombe
PFams: AA_permease, AA_permease_2
580 amino acids: PaperBLAST, CDD, CharProtDB::CH_125310
46% identical to

AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
PFams: AA_permease, AA_permease_2
473 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_17670
44% identical to

Q4KIP0 Aromatic amino acid transport protein AroP
466 amino acids: PaperBLAST, CDD

GAP5_CANAL / A0A1D8PMB1 Amino-acid permease GAP5 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: AA_permease, AA_permease_2
618 amino acids: PaperBLAST, CDD, SwissProt::A0A1D8PMB1
46% identical to

TC 2.A.3.1.23 / P0AAE2 ProY of 457 aas and 12 TMSs from Escherichia coli (strain K12)
PFams: AA_permease_2, Spore_permease, AA_permease
457 amino acids: PaperBLAST, CDD, TCDB::P0AAE2
44% identical to

YHE1_SCHPO / Q9HDV2 Uncharacterized amino-acid permease PB2B2.01 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: AA_permease, AA_permease_2
585 amino acids: PaperBLAST, CDD, SwissProt::Q9HDV2
46% identical to

TC 2.A.3.1.6 / P37460 Proline-specific permease (ProY) from Salmonella typhimurium
PFams: AA_permease_2, Spore_permease, AA_permease
456 amino acids: PaperBLAST, CDD, TCDB::P37460
43% identical to

GAP4_CANAL / Q59WB3 S-adenosylmethionine permease GAP4; SAM permease; Amino-acid permease GAP4 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
TC 2.A.3.10.25 / Q59WB3 Arginine transporter, GAP4 from Candida albicans
CH_123720 potential general amino acid permease from Candida albicans
PFams: AA_permease, AA_permease_2
607 amino acids: PaperBLAST, CDD, SwissProt::Q59WB3
44% identical to

HIP1_YEAST / P06775 Histidine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.1 / P06775 High affinity histidine permease (also implicated in Mn2+ efflux; Co2+, Ni2+, Zn2+ and Cu2+ uptake) from Saccharomyces cerevisiae (Baker's yeast)
GI|1323339 histidine permease from Saccharomyces cerevisiae
PFams: AA_permease_2, AA_permease
603 amino acids: PaperBLAST, CDD, CharProtDB::CH_091109
45% identical to

GABP_BACSU / P46349 GABA permease; 4-amino butyrate transport carrier; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis
PFams: Spore_permease, AA_permease_2, AA_permease
469 amino acids: PaperBLAST, CDD, SwissProt::P46349
42% identical to

TC 2.A.3.1.12 / Q46065 Aromatic amino acid permease, AroP from Corynebacterium glutamicum (Brevibacterium flavum)
PFams: AA_permease_2, Spore_permease, AA_permease
463 amino acids: PaperBLAST, CDD

AGP1_YEAST / P25376 General amino acid permease AGP1; Asparagine/glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.7 / P25376 Asn/Gln permease from Saccharomyces cerevisiae (Baker's yeast)
RF|NP_009905.3 general amino acid permease AGP1 from Saccharomyces cerevisiae
PFams: AA_permease_2, AA_permease
633 amino acids: PaperBLAST, CDD, CharProtDB::CH_091105
42% identical to

SAM3_YEAST / Q08986 S-adenosylmethionine permease SAM3; S-adenosylmethionine metabolism protein 3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.15 / Q08986 S-adenosylmethionine uptake permease, SAM3 (also takes up polyamines, glutamate, lysine and the toxic S-adenosylmethionine analogue sinefungin) from Saccharomyces cerevisiae (Baker's yeast)
RF|NP_015049.1 S-adenosylmethionine permease SAM3 from Saccharomyces cerevisiae
PFams: AA_permease_2, AA_permease
587 amino acids: PaperBLAST, CDD, CharProtDB::CH_091257
44% identical to

BAUD_PSEAE / Q9I703 Probable GABA permease; 4-amino butyrate transport carrier; Gamma-aminobutyrate permease from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: AA_permease_2, AA_permease
475 amino acids: PaperBLAST, CDD, SwissProt::Q9I703
41% identical to

CYCA_ECOL6 / A0A0H2VDI7 D-serine/D-alanine/glycine transporter from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)
PFams: AA_permease, AA_permease_2
470 amino acids: PaperBLAST, CDD, SwissProt::A0A0H2VDI7
40% identical to

b4208 D-serine/alanine/glycine/:H⁺symporter from Escherichia coli K-12 substr. MG1655
P0AAE0 D-serine/alanine/glycine/:H⁺symporter from Escherichia coli (strain K12)
CYCA_ECOLI / P0AAE0 D-serine/D-alanine/glycine transporter from Escherichia coli (strain K12)
TC 2.A.3.1.7 / P0AAE0 D-Serine/D-alanine/glycine/D-cycloserine:H+ symporter from Escherichia coli
PFams: AA_permease, AA_permease_2
470 amino acids: PaperBLAST, CDD, SwissProt::P0AAE0
40% identical to

MMP1_YEAST / Q12372 S-methylmethionine permease 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.16 / Q12372 S-methylmethionine uptake permease, Mmp1 from Saccharomyces cerevisiae (Baker's yeast)
RF|NP_013039.1 S-methylmethionine permease 1 from Saccharomyces cerevisiae
PFams: AA_permease_2, AA_permease
583 amino acids: PaperBLAST, CDD, CharProtDB::CH_091514
40% identical to

BAP2_YEAST / P38084 Leu/Val/Ile amino-acid permease; Branched-chain amino-acid permease 2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: AA_permease, AA_permease_2
609 amino acids: PaperBLAST, CDD, SwissProt::P38084
44% identical to

TC 2.A.3.10.6 / P38084 Leu/Val/Ile amino acid permease from Saccharomyces cerevisiae (Baker's yeast)
RF|NP_009624.1 Leu/Val/Ile amino-acid permease from Saccharomyces cerevisiae
PFams: AA_permease, AA_permease_2
609 amino acids: PaperBLAST, CDD, CharProtDB::CH_091448
44% identical to

TAT2_YEAST / P38967 Tryptophan permease; Tryptophan amino acid transporter from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.8 / P38967 Tryptophan permease, Tat2. Regulated via endocytosis by ATP-binding Cassette Transporters, Pdr5 (3.A.1.205.1) and Yor1 (3.A.208.3) as well as a seven-transmembrane protein, RSB1 (9.A.27.1.2) from Saccharomyces cerevisiae (Baker's yeast)
RF|NP_014622.1 tryptophan permease from Saccharomyces cerevisiae
PFams: AA_permease_2, AA_permease
592 amino acids: PaperBLAST, CDD, CharProtDB::CH_091156
43% identical to

b2663 4-aminobutanoate:H⁺ symporter from Escherichia coli K-12 substr. MG1655
P25527 4-aminobutanoate:H⁺ symporter from Escherichia coli (strain K12)
GABP_ECOLI / P25527 GABA permease; 4-amino butyrate transport carrier; Gamma-aminobutyrate permease from Escherichia coli (strain K12)
TC 2.A.3.1.4 / P25527 γ-aminobutyrate:H+ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005) from Escherichia coli
PFams: AA_permease, AA_permease_2
466 amino acids: PaperBLAST, CDD, SwissProt::P25527
41% identical to

GNP1_YEAST / P48813 High-affinity glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.5 / P48813 High affinity glutamine permease from Saccharomyces cerevisiae (Baker's yeast)
GI|927778 high-affinity glutamine permease from Saccharomyces cerevisiae
PFams: AA_permease_2, AA_permease
663 amino acids: PaperBLAST, CDD, CharProtDB::CH_090998
41% identical to

BAP3_YEAST / P41815 Valine amino-acid permease; Branched-chain amino-acid permease 3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
TC 2.A.3.10.27 / P41815 Valine amino-acid permease (Branched-chain amino-acid permease 3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
PFams: AA_permease, AA_permease_2
604 amino acids: PaperBLAST, CDD, SwissProt::P41815
42% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for aroP.)

FYWP_LACLM / A2RMP5 Aromatic amino acid permease FywP from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: AA_permease_2, AA_permease
457 amino acids: PaperBLAST, CDD, SwissProt::A2RMP5
95% identical to

TC 2.A.3.1.22 / F2HN33 Transporter for phenylalainine, tyrosine and tryptophan of 449 aas and 12 TMSs, FywP or YsjA from Lactococcus lactis subsp. lactis (strain CV56)
PFams: AA_permease_2, AA_permease
449 amino acids: PaperBLAST, CDD

AO356_18530 L-tyrosine transporter from Pseudomonas fluorescens FW300-N2C3
PFams: AA_permease, AA_permease_2
471 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_18530
72% identical to

Q4KIP0 Aromatic amino acid transport protein AroP
466 amino acids: PaperBLAST, CDD