Other Characterized Proteins Similar to ecfA1

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to ecfA1

Finding the characterized proteins for ecfA1 (energy-coupling factor transporter, ATPase 1 (A1) component) in L-tryptophan catabolism

Or see clustering for step ecfA1

Or see all steps for L-tryptophan catabolism

Or cluster curated proteins matching a keyword

Definition of ecfA1

UniProt sequence P40735: RecName: Full=Energy-coupling factor transporter ATP-binding protein EcfA1 {ECO:0000255|HAMAP-Rule:MF_01710}; Short=ECF transporter A component EcfA {ECO:0000255|HAMAP-Rule:MF_01710}; EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_01710};
Ignore hits to Q839D5 when looking for 'other' hits (Cobalt import ATP-binding protein CbiO 1, component of ATP-dependent folic acid uptake porter, FolT/EcfT/EcfA1/EcfA2)
Ignore hits to Q035B2 when looking for 'other' hits (Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.-)
Ignore hits to A2RI01 when looking for 'other' hits (Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.-. Energy-coupling factor transporter ATP-binding protein EcfA 1, component of The biotin uptake system, BioMNY. The 3-d structure of the EcfS subunit, BioY, at 2.1Å resolution is known (Berntsson et al., 2012). BioY and ThiT from L. lactis)
Ignore hits to Q5M243 when looking for 'other' hits (Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.-. Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU)
Ignore hits to Q03PY5 when looking for 'other' hits (Energy-coupling factor transporter ATP-binding protein EcfA1, component of The folate transporter, FolT/EcfAA''T (The 3-d structure is known to 3.0Å resolution (Xu et al. 2013; 4HUQ))
Ignore hits to G12WB-158-MONOMER when looking for 'other' hits (energy-coupling factor transporter ATP-bindind protein 1)
Ignore hits to Q03ZL6 when looking for 'other' hits (Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.-)
Comment: Orthologs may be annotated as ecfA1 or cbiO; these have the same function (but might not be part of a tryptophan transporting system).

Fetched 1 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 13 other characterized sequences. (Found 13 hits including self hits.)

Removing ignored items reduces this to 6 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for ecfA1.)

Q18CI9 energy-coupling factor transporter ATP-bindind protein 2 from Clostridioides difficile (strain 630)
PFams: ABC_tran, AAA_21
288 amino acids: PaperBLAST, CDD, metacyc::G12WB-159-MONOMER
41% identical to

P40735 Energy-coupling factor transporter ATP-binding protein EcfA1 {ECO:0000255|HAMAP-Rule:MF_01710}; Short=ECF transporter A component EcfA {ECO:0000255|HAMAP-Rule:MF_01710}; EC=7.-.-.- {ECO:0000255|HAMAP-Rule:MF_01710}
281 amino acids: PaperBLAST, CDD

CBIO_RHOCB / O68106 Cobalt import ATP-binding protein CbiO; Energy-coupling factor transporter ATP-binding protein CbiO; ECF transporter A component CbiO; EC 7.2.2.- from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
TC 3.A.1.23.8 / O68106 Cobalt import ATP-binding protein CbiO, component of Ni2+/Co2+ uptake porter, CbiMNOQ (CbiM, 222 aas, 5 TMSs; CbiN, 103 aas, 2 TMSs; CbiO, 280 aas, 0 TMSs; CbiQ, 244 aas, 5 TMSs) from Rhodobacter capsulatus (strain ATCC BAA-309 / NBRC 16581 / SB1003)
PFams: ABC_tran, AAA_21
Heteromeric, 280 amino acids: PaperBLAST, CDD, SwissProt::O68106
40% identical to

GBUA_LISM4 / Q9RR46 Glycine betaine/carnitine transport ATP-binding protein GbuA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S)
PFams: ABC_tran, CBS, CBS
397 amino acids: PaperBLAST, CDD, SwissProt::Q9RR46
41% identical to

TC 3.A.1.12.5 / Q9RQ06 BusAA, component of Uptake system for glycine-betaine (high affinity) and proline (low affinity) (OpuAA-OpuABC) or BusAA-ABC of Lactococcus lactis). BusAA, the ATPase subunit, has a C-terminal tandem cystathionine β-synthase (CBS) domain which is the cytoplasmic K+ sensor for osmotic stress (osmotic strength)while the BusABC subunit has the membrane and receptor domains fused to each other (Biemans-Oldehinkel et al., 2006; Mahmood et al., 2006; Gul et al. 2012). An N-terminal amphipathic α-helix of OpuA is necessary for high activity but is not critical for biogenesis or the ionic regulation of transport from Lactococcus lactis
PFams: ABC_tran, CBS
Heteromeric, 407 amino acids: PaperBLAST, CDD, TCDB::Q9RQ06
42% identical to

AO356_09610 ABC transporter for L-Histidine, ATPase component from Pseudomonas fluorescens FW300-N2C3
PFams: ABC_tran
Heteromeric, 276 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_09610
40% identical to

OPUAA_BACSU / P46920 Glycine betaine transport ATP-binding protein OpuAA; Quaternary-amine-transporting ATPase; EC 7.6.2.9 from Bacillus subtilis (strain 168)
P46920 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis
TC 3.A.1.12.2 / P46920 OPAA aka OpuAA, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis
PFams: ABC_tran, CBS
Heteromeric, 418 amino acids: PaperBLAST, CDD, BRENDA::P46920
40% identical to

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for ecfA1.)

ECFA1_LACP3 / Q035B2 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.- from Lactobacillus paracasei (strain ATCC 334 / BCRC 17002 / CIP 107868 / KCTC 3260 / NRRL B-441)
PFams: ABC_tran
278 amino acids: PaperBLAST, CDD, SwissProt::Q035B2
58% identical to

TC 3.A.1.26.10 / TC 3.A.1.26.7 / Q839D5 Cobalt import ATP-binding protein CbiO 1, component of ATP-dependent folic acid uptake porter, FolT/EcfT/EcfA1/EcfA2 from Enterococcus faecalis
PFams: ABC_tran, SMC_N
Heteromeric, 279 amino acids: PaperBLAST, CDD, TCDB::Q839D5
58% identical to

ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
PFams: ABC_tran
Heteromeric, 276 amino acids: PaperBLAST, CDD, SwissProt::Q5M243
55% identical to

ECFA1_LACLM / A2RI01 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA; EC 7.-.-.- from Lactococcus lactis subsp. cremoris (strain MG1363)
TC 3.A.1.25.4 / A2RI01 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of The biotin uptake system, BioMNY. The 3-d structure of the EcfS subunit, BioY, at 2.1Å resolution is known (Berntsson et al., 2012). BioY and ThiT from L. lactis from Lactococcus lactis subsp. cremoris (strain MG1363)
PFams: ABC_tran
Heteromeric, 277 amino acids: PaperBLAST, CDD, SwissProt::A2RI01
55% identical to

TC 3.A.1.26.9 / TC 3.A.1.28.2 / Q03PY5 Energy-coupling factor transporter ATP-binding protein EcfA1, component of The folate transporter, FolT/EcfAA''T (The 3-d structure is known to 3.0Å resolution (Xu et al. 2013; 4HUQ) from Lactobacillus brevis (strain ATCC 367 / JCM 1170)
PFams: ABC_tran
Heteromeric, 279 amino acids: PaperBLAST, CDD, TCDB::Q03PY5
53% identical to

Q18CJ0 energy-coupling factor transporter ATP-bindind protein 1 from Clostridioides difficile (strain 630)
PFams: ABC_tran, SMC_N
277 amino acids: PaperBLAST, CDD, metacyc::G12WB-158-MONOMER
49% identical to

ECFA1_LEUMM / Q03ZL6 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523)
PFams: SMC_N, ABC_tran
272 amino acids: PaperBLAST, CDD, SwissProt::Q03ZL6
49% identical to