Other Characterized Proteins Similar to kyn

Finding the characterized proteins for kyn (kynureninase) in L-tryptophan catabolism

Or see clustering for step kyn

Or see all steps for L-tryptophan catabolism

Or cluster curated proteins matching a keyword

Definition of kyn

• Curated proteins or TIGRFams with EC 3.7.1.3
• Comment: 3-hydroxykynurenine hydrolase and kynurenine hydrolase are described by the same EC number.

Fetched 13 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 2 other characterized sequences. (Found 15 hits including self hits.)

There are also 1 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for kyn.)

D6R233 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus
PFams: Aminotran_5
299 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19504
79% identical to

D6R244 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus
PFams: Aminotran_5
420 amino acids: PaperBLAST, CDD

C0LTN1 3-hydroxy-4-methyl-L-kynurenine hydrolase from Streptosporangium sibiricum
PFams: Aminotran_5
393 amino acids: PaperBLAST, CDD, metacyc::MONOMER-19742
42% identical to

D6R244 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus
PFams: Aminotran_5
420 amino acids: PaperBLAST, CDD

HMM-only sequences

(Since these sequences' annotations are outside the definition for kyn, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

D6R244 3-hydroxy-4-methyl-D-kynurenine hydrolase monomer from Streptomyces anulatus
PFams: Aminotran_5
420 amino acids: PaperBLAST, CDD