Other Characterized Proteins Similar to pcaF

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to pcaF

Finding the characterized proteins for pcaF (succinyl-CoA:acetyl-CoA C-succinyltransferase) in L-tryptophan catabolism

Or see clustering for step pcaF

Or see all steps for L-tryptophan catabolism

Or cluster curated proteins matching a keyword

Definition of pcaF

Curated proteins or TIGRFams with EC 2.3.1.174

Fetched 5 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 42 other characterized sequences. (Found 47 hits including self hits.)

There are also 1 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for pcaF.)

A0A1N7U0F8 acetyl-CoA C-acetyltransferase (EC 2.3.1.16) from Pseudomonas simiae
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
393 amino acids: PaperBLAST, CDD, metacyc::MONOMER-20831
48% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

AO356_21640 acetyl-CoA C-acetyltransferase [EC: 2.3.1.9] from Pseudomonas fluorescens FW300-N2C3
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
393 amino acids: PaperBLAST, CDD, reanno::pseudo5_N2C3_1:AO356_21640
48% identical to

PCAF_PSEKB / Q8VPF1 Beta-ketoadipyl-CoA thiolase; 3-oxoadipyl-CoA thiolase; EC 2.3.1.174 from Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

b2224 acetyl-CoA acetyltransferase (EC 2.3.1.16; EC 2.3.1.9) from Escherichia coli K-12 substr. MG1655
P76461 acetyl-CoA acetyltransferase (EC 2.3.1.16) from Escherichia coli (strain K12)
PFams: Thiolase_N, Thiolase_C
394 amino acids: PaperBLAST, CDD, ecocyc::ACETYL-COA-ACETYLTRANSFER-MONOMER
47% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

PfGW456L13_2411 Acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Pseudomonas fluorescens GW456-L13
PFams: Thiolase_N, Thiolase_C
393 amino acids: PaperBLAST, CDD, reanno::pseudo13_GW456_L13:PfGW456L13_2411
47% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

A5N3I5 acetyl-CoA acetyltransferase (EC 2.3.1.16) from Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
PFams: Thiolase_N, Thiolase_C
393 amino acids: PaperBLAST, CDD, metacyc::MONOMER-13468
47% identical to

THIL_ALLVD / P45369 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Allochromatium vinosum (strain ATCC 17899 / DSM 180 / NBRC 103801 / NCIMB 10441 / D) (Chromatium vinosum)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
394 amino acids: PaperBLAST, CDD, SwissProt::P45369
47% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

P45359 acetoacetyl-CoA thiolase monomer (EC 2.3.1.16) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
P45359 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Clostridium acetobutylicum
PFams: Thiolase_N, SpoVAD, ketoacyl-synt, Thiolase_C
392 amino acids: PaperBLAST, CDD, BRENDA::P45359
47% identical to

P14611 acetyl-CoA acetyltransferase subunit (EC 2.3.1.16) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
THIL_CUPNH / P14611 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
393 amino acids: PaperBLAST, CDD, SwissProt::P14611
46% identical to

Shewana3_0023 Acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Shewanella sp. ANA-3
PFams: Thiolase_N, Thiolase_C
387 amino acids: PaperBLAST, CDD, reanno::ANA3:7022768
45% identical to

b1397 β-ketoadipyl-CoA thiolase (EC 2.3.1.223; EC 2.3.1.174) from Escherichia coli K-12 substr. MG1655
P0C7L2 β-ketoadipyl-CoA thiolase (EC 2.3.1.223; EC 2.3.1.174) from Escherichia coli (strain K12)
PAAJ_ECOLI / P0C7L2 3-oxoadipyl-CoA/3-oxo-5,6-dehydrosuberyl-CoA thiolase; EC 2.3.1.174; EC 2.3.1.223 from Escherichia coli (strain K12)
PFams: Thiolase_N, Thiolase_C
401 amino acids: PaperBLAST, CDD

Sama_0031 Acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Shewanella amazonensis SB2B
PFams: Thiolase_N, Thiolase_C
387 amino acids: PaperBLAST, CDD, reanno::SB2B:6935813
46% identical to

HP15_2695 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) from Marinobacter adhaerens HP15
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
415 amino acids: PaperBLAST, CDD

THIL_THIVI / P45363 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Thiocystis violacea
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
394 amino acids: PaperBLAST, CDD, SwissProt::P45363
45% identical to

Q51956 subunit of β-ketoadipyl CoA thiolase (EC 2.3.1.174; EC 2.3.1.16) from Pseudomonas putida
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
400 amino acids: PaperBLAST, CDD

THLA_SYNWW / Q0AVM3 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; EC 2.3.1.9 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen)
PFams: Thiolase_N, Thiolase_C
396 amino acids: PaperBLAST, CDD, SwissProt::Q0AVM3
45% identical to

Q0KBP1 β-ketothiolase (EC 2.3.1.16) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
BKTB_CUPNH / Q0KBP1 Beta-ketothiolase BktB; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; EC 2.3.1.16; EC 2.3.1.9 from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
394 amino acids: PaperBLAST, CDD, SwissProt::Q0KBP1
45% identical to

SMc03879 Acetyl-CoA acetyltransferase (EC 2.3.1.9) from Sinorhizobium meliloti 1021
THIL_RHIME / P50174 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
PFams: Thiolase_N, Thiolase_C
393 amino acids: PaperBLAST, CDD, SwissProt::P50174
45% identical to

b3845 3-ketoacyl-CoA thiolase (EC 2.3.1.16) from Escherichia coli K-12 substr. MG1655
P21151 3-ketoacyl-CoA thiolase (EC 2.3.1.16) from Escherichia coli (strain K12)
FADA_ECOLI / P21151 3-ketoacyl-CoA thiolase FadA; Acetyl-CoA acyltransferase; Beta-ketothiolase; Fatty acid oxidation complex subunit beta; EC 2.3.1.16 from Escherichia coli (strain K12)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
Heteromeric, 387 amino acids: PaperBLAST, CDD, SwissProt::P21151
45% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

Q3IZW1 acetyl-CoA acetyltransferase (EC 2.3.1.16) from Rhodobacter sphaeroides (strain ATCC 17023 / 2.4.1 / NCIB 8253 / DSM 158)
PFams: Thiolase_N, Thiolase_C
391 amino acids: PaperBLAST, CDD, metacyc::MONOMER-13585
44% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

FADA_BACSU / O32177 3-ketoacyl-CoA thiolase; Acetyl-CoA acyltransferase; Beta-ketothiolase; EC 2.3.1.16 from Bacillus subtilis (strain 168)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
391 amino acids: PaperBLAST, CDD, SwissProt::O32177
44% identical to

THIL_ZOORA / P07097 Acetyl-CoA acetyltransferase; Acetoacetyl-CoA thiolase; Beta-ketothiolase; EC 2.3.1.9 from Zoogloea ramigera
PFams: Thiolase_N, Thiolase_C
392 amino acids: PaperBLAST, CDD, SwissProt::P07097
44% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

Y0859_MYCTU / O53871 Putative acyltransferase Rv0859; EC 2.3.1.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
403 amino acids: PaperBLAST, CDD, SwissProt::O53871
43% identical to

P28790 acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Pseudomonas fragi
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
391 amino acids: PaperBLAST, CDD, BRENDA::P28790
43% identical to

P42765 3-ketoacyl-CoA thiolase, mitochondrial (EC 2.3.1.16) from Homo sapiens
THIM_HUMAN / P42765 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; T1; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Homo sapiens (Human)
P42765 acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Homo sapiens
PFams: Thiolase_N, Thiolase_C
397 amino acids: PaperBLAST, CDD, BRENDA::P42765
43% identical to

I6XHJ3 3-oxo-acyl CoA thiolase (EC 2.3.1.16) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
386 amino acids: PaperBLAST, CDD, metacyc::G185E-7833-MONOMER
43% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

PGA1_c03400 acetyl-CoA:acetyl-CoA C-acetyltransferase / acetyl-CoA:propanoyl-CoA 2-C-acetyltransferase (EC 2.3.1.9; EC 2.3.1.16) from Phaeobacter inhibens BS107
PFams: Thiolase_N, Thiolase_C
391 amino acids: PaperBLAST, CDD, reanno::Phaeo:GFF329
43% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

B1YB71 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Pyrobaculum neutrophilum
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
392 amino acids: PaperBLAST, CDD, BRENDA::B1YB71
43% identical to

THIM_RAT / P13437 3-ketoacyl-CoA thiolase, mitochondrial; Acetyl-CoA acetyltransferase; Acetyl-CoA acyltransferase; Acyl-CoA hydrolase, mitochondrial; Beta-ketothiolase; Mitochondrial 3-oxoacyl-CoA thiolase; EC 2.3.1.16; EC 2.3.1.9; EC 3.1.2.-; EC 3.1.2.1; EC 3.1.2.2 from Rattus norvegicus (Rat)
PFams: Thiolase_N, Thiolase_C
397 amino acids: PaperBLAST, CDD, SwissProt::P13437
43% identical to

Q6N3H9 3-oxopimeloyl-CoA:CoA acetyltransferase from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
PFams: Thiolase_N, Thiolase_C
395 amino acids: PaperBLAST, CDD, metacyc::MONOMER-20679
42% identical to

Q88L01 FadA (EC 2.3.1.16) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
391 amino acids: PaperBLAST, CDD, metacyc::G1G01-2278-MONOMER
42% identical to

Q9HZJ3 fatty acid oxidation complex β subunit (EC 2.3.1.16) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
391 amino acids: PaperBLAST, CDD, metacyc::MONOMER-17590
42% identical to

Q0KAI3 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Cupriavidus necator
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
392 amino acids: PaperBLAST, CDD, BRENDA::Q0KAI3
42% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

B7XEI5 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Ostrinia scapulalis
PFams: Thiolase_N, Thiolase_C
396 amino acids: PaperBLAST, CDD, BRENDA::B7XEI5
42% identical to

HP15_1513 Acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Marinobacter adhaerens HP15
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
374 amino acids: PaperBLAST, CDD, reanno::Marino:GFF1551
43% identical to

Q9FD70 acetyl-CoA acetyltransferase/HMG-CoA reductase (EC 1.1.1.34; EC 2.3.1.16) from Enterococcus faecalis
PFams: Thiolase_N, Thiolase_C, HMG-CoA_red
803 amino acids: PaperBLAST, CDD, metacyc::MONOMER-18244
41% identical to

Q0K368 acetyl-CoA C-acetyltransferase (EC 2.3.1.9) from Cupriavidus necator
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
391 amino acids: PaperBLAST, CDD, BRENDA::Q0K368
41% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

BWI76_RS23710 3-keto-2-deoxy-D-ribonyl-CoA thiolase from Klebsiella michiganensis M5al
PFams: Thiolase_N, Thiolase_C
396 amino acids: PaperBLAST, CDD, reanno::Koxy:BWI76_RS23710
41% identical to

Q9BWD1 acetyl-CoA acetyltransferase (EC 2.3.1.16) from Homo sapiens
THIC_HUMAN / Q9BWD1 Acetyl-CoA acetyltransferase, cytosolic; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase; EC 2.3.1.9 from Homo sapiens (Human)
PFams: Thiolase_N, Thiolase_C
397 amino acids: PaperBLAST, CDD, SwissProt::Q9BWD1
41% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

THIKB_RAT / P07871 3-ketoacyl-CoA thiolase B, peroxisomal; Acetyl-CoA acyltransferase B; Beta-ketothiolase B; Peroxisomal 3-oxoacyl-CoA thiolase B; EC 2.3.1.155; EC 2.3.1.16; EC 2.3.1.9 from Rattus norvegicus (Rat)
PFams: Thiolase_N, Thiolase_C
424 amino acids: PaperBLAST, CDD, SwissProt::P07871
41% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

THIKA_MOUSE / Q921H8 3-ketoacyl-CoA thiolase A, peroxisomal; Acetyl-CoA acyltransferase A; Beta-ketothiolase A; Peroxisomal 3-oxoacyl-CoA thiolase A; EC 2.3.1.16 from Mus musculus (Mouse)
Q921H8 acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Mus musculus
PFams: Thiolase_N, Thiolase_C
424 amino acids: PaperBLAST, CDD, BRENDA::Q921H8
41% identical to

THIL_SYNY3 / P73825 Acetyl-CoA acetyltransferase; Beta-ketothiolase PhaA; EC 2.3.1.9 from Synechocystis sp. (strain PCC 6803 / Kazusa)
PFams: Thiolase_N, Thiolase_C
396 amino acids: PaperBLAST, CDD, SwissProt::P73825
40% identical to

Q51956 subunit of β-ketoadipyl CoA thiolase (EC 2.3.1.174; EC 2.3.1.16) from Pseudomonas putida
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
400 amino acids: PaperBLAST, CDD

THIKB_MOUSE / Q8VCH0 3-ketoacyl-CoA thiolase B, peroxisomal; Acetyl-CoA acyltransferase B; Beta-ketothiolase B; Peroxisomal 3-oxoacyl-CoA thiolase B; EC 2.3.1.155; EC 2.3.1.16; EC 2.3.1.9 from Mus musculus (Mouse)
Q8VCH0 acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Mus musculus
PFams: Thiolase_N, Thiolase_C
424 amino acids: PaperBLAST, CDD, BRENDA::Q8VCH0
40% identical to

Q51956 subunit of β-ketoadipyl CoA thiolase (EC 2.3.1.174; EC 2.3.1.16) from Pseudomonas putida
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
400 amino acids: PaperBLAST, CDD

I6XHI4 steroid 3-ketoacyl-CoA thiolase monomer (EC 2.3.1.16; EC 2.3.1.176) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
FADA5_MYCTU / I6XHI4 Steroid 3-ketoacyl-CoA thiolase; Acetyl-CoA acetyltransferase FadA5; Beta-ketoacyl-CoA thiolase; EC 2.3.1.16 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Thiolase_N, Thiolase_C
391 amino acids: PaperBLAST, CDD, SwissProt::I6XHI4
40% identical to

THIK5_ARATH / Q570C8 3-ketoacyl-CoA thiolase 5, peroxisomal; Acetyl-CoA acyltransferase 5; Beta-ketothiolase 5; Peroxisomal 3-oxoacyl-CoA thiolase 5; EC 2.3.1.16 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Thiolase_N, Thiolase_C
457 amino acids: PaperBLAST, CDD, SwissProt::Q570C8
40% identical to

Q845J8 β-ketoadipyl-CoA thiolase (EC 2.3.1.174; EC 2.3.1.223) from Pseudomonas sp. Y2
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
401 amino acids: PaperBLAST, CDD

P09110 3-ketoacyl-CoA thiolase, peroxisomal (EC 2.3.1.223; EC 2.3.1.16) from Homo sapiens
THIK_HUMAN / P09110 3-ketoacyl-CoA thiolase, peroxisomal; Acetyl-CoA acyltransferase; Beta-ketothiolase; Peroxisomal 3-oxoacyl-CoA thiolase; EC 2.3.1.16 from Homo sapiens (Human)
PFams: Thiolase_N, Thiolase_C
424 amino acids: PaperBLAST, CDD, SwissProt::P09110
40% identical to

HMM-only sequences

(Since these sequences' annotations are outside the definition for pcaF, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

HP15_2695 Beta-ketoadipyl CoA thiolase (EC 2.3.1.-) from Marinobacter adhaerens HP15
PFams: Thiolase_N, ketoacyl-synt, Thiolase_C
415 amino acids: PaperBLAST, CDD