GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to aacS

Finding the characterized proteins for aacS (acetoacetyl-CoA synthetase) in L-tyrosine catabolism

Or see clustering for step aacS

Or see all steps for L-tyrosine catabolism

Or cluster curated proteins matching a keyword

Definition of aacS

Fetched 9 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 3 other characterized sequences. (Found 12 hits including self hits.)

There are also 2 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for aacS.)

ACSF2_HUMAN / Q96CM8 Medium-chain acyl-CoA ligase ACSF2, mitochondrial; EC 6.2.1.2 from Homo sapiens (Human)
PFams: AMP-binding, AMP-binding_C
615 amino acids: PaperBLAST, CDD, SwissProt::Q96CM8
46% identical to

Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD

SIDI_ASPFU / Q4WR83 Acyl-CoA ligase sidI; Siderophore biosynthesis protein I; EC 6.2.1.- from Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
PFams: AMP-binding, AMP-binding_C
590 amino acids: PaperBLAST, CDD, SwissProt::Q4WR83
41% identical to

Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD

SID4_AJECA / B2KWI3 Acyl-CoA ligase SID4; Siderophore biosynthesis cluster protein SID4; EC 6.2.1.- from Ajellomyces capsulatus (Darling's disease fungus) (Histoplasma capsulatum)
PFams: AMP-binding, AMP-binding_C
589 amino acids: PaperBLAST, CDD, SwissProt::B2KWI3
42% identical to

Ac3H11_3009 Acetoacetate--CoA ligase (EC 6.2.1.16) from Acidovorax sp. GW101-3H11
PFams: AMP-binding, AMP-binding_C
578 amino acids: PaperBLAST, CDD

HMM-only sequences

(Since these sequences' annotations are outside the definition for aacS, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

Q5P8R9 4-hydroxybenzoyl-acetyl-CoA synthetase from Aromatoleum aromaticum (strain EbN1)
PFams: ACAS_N, AMP-binding
664 amino acids: PaperBLAST, CDD

VRTB_PENAE / D7PHZ3 Malonamoyl-CoA synthetase vrtB; Viridicatumtoxin synthesis protein B; EC 6.2.1.- from Penicillium aethiopicum
PFams: ACAS_N, AMP-binding, AMP-binding_C
723 amino acids: PaperBLAST, CDD