GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for hmgA (homogentisate dioxygenase) in L-tyrosine catabolism

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Definition of hmgA

Fetched 14 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 14 of these sequences

Found 2 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 433-484 amino acids (not heteromeric)

B8YB76 homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Bos taurus
PFams: HgmA
445 amino acids: PaperBLAST, CDD, Compare to cluster

Q6JDV6 homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Exophiala lecanii-corni
PFams: HgmA
484 amino acids: PaperBLAST, CDD, Compare to cluster

HGD_PSEPK / Q88E47 Homogentisate 1,2-dioxygenase; HGDO; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
Q88E47 homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Pseudomonas putida
PFams: HgmA
433 amino acids: PaperBLAST, CDD, Compare to cluster

HGD_HUMAN / Q93099 Homogentisate 1,2-dioxygenase; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Homo sapiens (Human)
Q93099 homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Homo sapiens
Q93099 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Homo sapiens
PFams: HgmA
445 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ZRA2 homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Arabidopsis thaliana
PFams: HgmA
461 amino acids: PaperBLAST, CDD, Compare to cluster

GI|2832726 homogentisate dioxygenase; EC 1.13.11.5; EC 1.13.11.15 from Emericella nidulans
PFams: HgmA
448 amino acids: PaperBLAST, CDD, Compare to cluster

HGD_PSEPU / Q6EMI9 Homogentisate 1,2-dioxygenase; HGDO; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Pseudomonas putida (Arthrobacter siderocapsulatus)
PFams: HgmA
433 amino acids: PaperBLAST, CDD, Compare to cluster

HGD_RHIME / Q9X4F5 Homogentisate 1,2-dioxygenase; HGDO; Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase; EC 1.13.11.5 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
PFams: HgmA
453 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS31275 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Cupriavidus basilensis 4G11
PFams: HgmA
449 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_4962 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Pseudomonas fluorescens GW456-L13
PFams: HgmA
434 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_15550 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Pseudomonas fluorescens FW300-N2E3
PFams: HgmA
434 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_5290 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Pseudomonas fluorescens FW300-N2E2
PFams: HgmA
434 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 379-386 amino acids (not heteromeric)

SO1963 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Shewanella oneidensis MR-1
PFams: HgmA
386 amino acids: PaperBLAST, CDD, Compare to cluster

Psest_3513 Homogentisate 1,2-dioxygenase (EC 1.13.11.5) from Pseudomonas stutzeri RCH2
PFams: HgmA
379 amino acids: PaperBLAST, CDD, Compare to cluster