GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for mmsA (methylmalonate-semialdehyde dehydrogenase) in L-valine catabolism

Or see other characterized proteins similar to mmsA

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Or cluster curated proteins matching a keyword

Definition of mmsA

Fetched 23 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 23 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 487-541 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

A0A081YAY7 malonate-semialdehyde dehydrogenase (EC 1.2.1.15); malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Pseudomonas sp.
PFams: Aldedh
498 amino acids: PaperBLAST, CDD, Compare to cluster

G5CZI2 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Oceanimonas doudoroffii
PFams: Aldedh
498 amino acids: PaperBLAST, CDD, Compare to cluster

P42412 (methyl)malonate-semialdehyde dehydrogenase monomer (EC 1.2.1.27; EC 1.2.1.18) from Bacillus subtilis (strain 168)
IOLA_BACSU / P42412 Malonate-semialdehyde dehydrogenase; MSA dehydrogenase; Methylmalonate-semialdehyde dehydrogenase; MMSA dehydrogenase; MMSDH; MSDH; EC 1.2.1.-; EC 1.2.1.27 from Bacillus subtilis (strain 168)
P42412 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Bacillus subtilis
PFams: Aldedh
487 amino acids: PaperBLAST, CDD, Compare to cluster

MMSA_HUMAN / Q02252 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Homo sapiens (Human)
Q02252 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Homo sapiens
PFams: Aldedh
535 amino acids: PaperBLAST, CDD, Compare to cluster

Q6Z4E4 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Oryza sativa
PFams: Aldedh
534 amino acids: PaperBLAST, CDD, Compare to cluster

Q97YT9 methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) from Saccharolobus solfataricus
PFams: Aldedh
492 amino acids: PaperBLAST, CDD, Compare to cluster

Q9EQ20 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from HMM only) from Mus musculus
PFams: Aldedh
535 amino acids: PaperBLAST, CDD, Compare to cluster

P28810 methylmalonate-semialdehyde dehydrogenase subunit (EC 1.2.1.27) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
MMSA_PSEAE / P28810 Methylmalonate-semialdehyde dehydrogenase [acylating]; MMSDH; EC 1.2.1.27 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, Compare to cluster

MMSA_RAT / Q02253 Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrial; MMSDH; Malonate-semialdehyde dehydrogenase [acylating]; Aldehyde dehydrogenase family 6 member A1; EC 1.2.1.18; EC 1.2.1.27 from Rattus norvegicus (Rat)
PFams: Aldedh
535 amino acids: PaperBLAST, CDD, Compare to cluster

BAUC_PSEAE / Q9I702 Putative 3-oxopropanoate dehydrogenase; EC 1.2.1.- (from HMM only) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, Compare to cluster

Q8VUC5 methylmalonate-semialdehyde dehydrogenase subunit (EC 1.2.1.27) from Burkholderia cepacia
PFams: Aldedh
508 amino acids: PaperBLAST, CDD, Compare to cluster

C8YX90 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from HMM only) from Halomonas sp. HTNK1
PFams: Aldedh
503 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1D8PM94 malonate semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.18) (from HMM only) from Candida albicans (strain SC5314 / ATCC MYA-2876)
PFams: Aldedh
541 amino acids: PaperBLAST, CDD, Compare to cluster

CCNA_01360 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) from Caulobacter crescentus NA1000
PFams: Aldedh, LuxC
500 amino acids: PaperBLAST, CDD, Compare to cluster

BWI76_RS03070 Methylmalonate-semialdehyde dehydrogenase [inositol] (EC 1.2.1.27) from Klebsiella michiganensis M5al
PFams: Aldedh
501 amino acids: PaperBLAST, CDD, Compare to cluster

SMc00781 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from HMM only) from Sinorhizobium meliloti 1021
PFams: Aldedh
498 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_10925 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from HMM only) from Pseudomonas simiae WCS417
PFams: Aldedh
499 amino acids: PaperBLAST, CDD, Compare to cluster

Psest_2436 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas stutzeri RCH2
PFams: Aldedh
503 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_5146 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas fluorescens GW456-L13
PFams: Aldedh
508 amino acids: PaperBLAST, CDD, Compare to cluster

Pf1N1B4_1229 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas fluorescens FW300-N1B4
PFams: Aldedh
505 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_05990 Methylmalonate-semialdehyde dehydrogenase (EC 1.2.1.27) from Pseudomonas fluorescens FW300-N2E3
PFams: Aldedh
507 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_23175 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from HMM only) from Pseudomonas fluorescens FW300-N2C3
PFams: Aldedh
500 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_515 malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18) (from HMM only) from Pseudomonas fluorescens FW300-N2E2
PFams: Aldedh
500 amino acids: PaperBLAST, CDD, Compare to cluster