GapMind for catabolism of small carbon sources

 

Other Characterized Proteins Similar to mmsB

Finding the characterized proteins for mmsB (3-hydroxyisobutyrate dehydrogenase) in L-valine catabolism

Or see clustering for step mmsB

Or see all steps for L-valine catabolism

Or cluster curated proteins matching a keyword

Definition of mmsB

Fetched 7 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 2 other characterized sequences. (Found 9 hits including self hits.)

Removing ignored items reduces this to 1 close sequences.

There are also 1 HMM-only high-coverage hits.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for mmsB.)

HMGD_EUBBA / Q0QLF5 2-(hydroxymethyl)glutarate dehydrogenase; EC 1.1.1.291 from Eubacterium barkeri (Clostridium barkeri)
Q0QLF5 2-(hydroxymethyl)glutarate dehydrogenase subunit (EC 1.1.1.291) from Eubacterium barkeri
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
301 amino acids: PaperBLAST, CDD, SwissProt::Q0QLF5
41% identical to

Psest_2438 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) from Pseudomonas stutzeri RCH2
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
296 amino acids: PaperBLAST, CDD

HMM-only sequences

(Since these sequences' annotations are outside the definition for mmsB, HMM hits that are over 40% similar to these sequences will be scored as moderate confidence.)

SERDH_PSEAE / Q9I5I6 NAD-dependent L-serine dehydrogenase; L-serine 3-dehydrogenase (NAD(+)); EC 1.1.1.387 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
Q9I5I6 L-serine 3-dehydrogenase (NAD+) (EC 1.1.1.387) from Pseudomonas aeruginosa
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
298 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for mmsB.)

D5MU22 aldehyde oxidase (EC 1.2.3.1) from Pseudomonas sp.
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
295 amino acids: PaperBLAST, CDD, BRENDA::D5MU22
95% identical to

Q76KL5 3-hydroxyisobutyrate dehydrogenase (EC 1.1.1.31) from Pseudomonas putida
Q76KL5 3-hydroxyisobutyrate dehydrogenase subunit (EC 1.1.1.31) from Pseudomonas putida
PFams: F420_oxidored, NAD_binding_2, NAD_binding_11
295 amino acids: PaperBLAST, CDD