Other Characterized Proteins Similar to natA

Finding the characterized proteins for natA (L-valine ABC transporter, ATPase component 1 (NatA)) in L-valine catabolism

Or see clustering for step natA

Or see all steps for L-valine catabolism

Or cluster curated proteins matching a keyword

Definition of natA

• Ignore hits to Q55164 when looking for 'other' hits (NatA aka BRAF aka SLR0467, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE)
• Curated sequence Q7A2H0: NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
• Comment: Synechocystis sp. NatABCDE TC 3.A.1.4.2) and a similar system from Anabaena (also known as N-I; TC 3.A.1.4.6) are reported to transport many amino acids. There isn't any data for valine transport in Synechocystis, but N-I from Anabaena is thought to contribute to the reuptake of valine that leaks from the cell (PMC4500139).

Fetched 1 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 4 other characterized sequences. (Found 5 hits including self hits.)

Removing ignored items reduces this to 3 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for natA.)

TC 3.A.1.4.3 / Q8VM83 BraF aka Bra2F, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae)
PFams: ABC_tran, AAA_21, BCA_ABC_TP_C
Heteromeric, 257 amino acids: PaperBLAST, CDD, TCDB::Q8VM83
42% identical to

TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 260 amino acids: PaperBLAST, CDD

TC 3.A.1.4.10 / Q8DQH8 ABC transporter ATP-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
PFams: AAA_23, ABC_tran, BCA_ABC_TP_C
Heteromeric, 254 amino acids: PaperBLAST, CDD, TCDB::Q8DQH8
41% identical to

TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 260 amino acids: PaperBLAST, CDD

TC 3.A.1.4.8 / P21629 High-affinity branched-chain amino acid transport ATP-binding protein BraF, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 255 amino acids: PaperBLAST, CDD, TCDB::P21629
41% identical to

TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 260 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for natA.)

TC 3.A.1.4.2 / Q55164 NatA aka BRAF aka SLR0467, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 267 amino acids: PaperBLAST, CDD, TCDB::Q55164
70% identical to

TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB)
PFams: ABC_tran, BCA_ABC_TP_C
Heteromeric, 260 amino acids: PaperBLAST, CDD