GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for prpB (2-methylisocitrate lyase) in L-valine catabolism

Or see other characterized proteins similar to prpB

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Or cluster curated proteins matching a keyword

Definition of prpB

Fetched 26 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 25 of these sequences

Found 2 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by cluster

Bacillus subtilis

MMGF_BACSU / P54528 2-methylisocitrate lyase; 2-MIC; MICL; EC 4.1.3.- from Bacillus subtilis (strain 168)
P54528 Methylisocitrate lyase (EC 4.1.3.30) from Bacillus subtilis
PFams: PEP_mutase, ICL
301 amino acids: PaperBLAST, CDD (Cluster 2)

Corynebacterium glutamicum

PRPB1_CORGL / Q8NSH8 Probable 2-methylisocitrate lyase 1; 2-MIC; MICL; (2R,3S)-2-methylisocitrate lyase; EC 4.1.3.30 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: PEP_mutase, ICL
305 amino acids: PaperBLAST, CDD (Cluster 2)

PRPB2_CORGL / Q8NSL2 Probable 2-methylisocitrate lyase 2; 2-MIC; MICL; (2R,3S)-2-methylisocitrate lyase; EC 4.1.3.30 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: PEP_mutase, ICL
307 amino acids: PaperBLAST, CDD (Cluster 2)

Cupriavidus basilensis

RR42_RS11260 Methylisocitrate lyase (EC 4.1.3.30) from Cupriavidus basilensis 4G11
PFams: PEP_mutase, ICL
302 amino acids: PaperBLAST, CDD (Cluster 2)

Cupriavidus necator

PRPB_CUPNE / Q937P0 2-methylisocitrate lyase; 2-MIC; MICL; (2R,3S)-2-methylisocitrate lyase; EC 4.1.3.30 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
PFams: PEP_mutase, ICL
302 amino acids: PaperBLAST, CDD (Cluster 2)

Q0KAG5 2-methylcitrate lyase (EC 4.1.3.30) from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337)
PFams: PEP_mutase, ICL
302 amino acids: PaperBLAST, CDD (Cluster 2)

Emericella nidulans

GI|61657961 methylisocitrate lyase precursor; EC 4.1.3.30 from Emericella nidulans
CH_122270 methylisocitrate lyase; EC 4.1.3.30 from Emericella nidulans
PFams: ICL, PEP_mutase
604 amino acids: PaperBLAST, CDD (Cluster 1)

ACEB_EMENI / C8V9Y5 Methylisocitrate lyase, mitochondrial; 2-methylisocitrate lyase, mitochondrial; EC 4.1.3.30 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
PFams: ICL, PEP_mutase
610 amino acids: PaperBLAST, CDD (Cluster 1)

ACEA_EMENI / P28298 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
PDB|1DQU_A isocitrate lyase; EC 4.1.3.1 from Emericella nidulans
PFams: ICL, PEP_mutase
538 amino acids: PaperBLAST, CDD (Cluster 1)

Escherichia coli

b0331 2-methylisocitrate lyase (EC 4.1.3.30) from Escherichia coli K-12 substr. MG1655
PRPB_ECOLI / P77541 2-methylisocitrate lyase; 2-MIC; MICL; (2R,3S)-2-methylisocitrate lyase; EC 4.1.3.30 from Escherichia coli (strain K12)
P77541 2-methylisocitrate lyase (EC 4.1.3.30) from Escherichia coli (strain K12)
PFams: PEP_mutase, ICL
296 amino acids: PaperBLAST, CDD (Cluster 2)

Hypocrea atroviridis

ACEB_HYPAI / G9NNY7 2-methylisocitrate lyase, mitochondrial; EC 4.1.3.30 from Hypocrea atroviridis (strain ATCC 20476 / IMI 206040) (Trichoderma atroviride)
PFams: ICL
561 amino acids: PaperBLAST, CDD (Cluster 1)

Kluyveromyces lactis

ACEA_KLULA / Q8NJ72 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
PFams: ICL, PEP_mutase
542 amino acids: PaperBLAST, CDD (Cluster 1)

Leptosphaeria maculans

ACEA_LEPMC / Q86ZF1 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Leptosphaeria maculans (Blackleg fungus) (Phoma lingam)
PFams: ICL, PEP_mutase
537 amino acids: PaperBLAST, CDD (Cluster 1)

Magnaporthe grisea

ACEA_MAGO7 / P0CT06 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
P0CT06 isocitrate lyase (EC 4.1.3.1) from Magnaporthe oryzae
CH_124286 isocitrate lyase from Magnaporthe grisea 70-15
PFams: ICL, PEP_mutase
547 amino acids: PaperBLAST, CDD (Cluster 1)

Magnaporthe oryzae

ACEA_MAGO7 / P0CT06 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)
P0CT06 isocitrate lyase (EC 4.1.3.1) from Magnaporthe oryzae
CH_124286 isocitrate lyase from Magnaporthe grisea 70-15
PFams: ICL, PEP_mutase
547 amino acids: PaperBLAST, CDD (Cluster 1)

Mycobacterium bovis

ACEA1_MYCTE / H8EVV4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
ACEA1_MYCBO / P0A5H4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; EC 4.1.3.1 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
ACEA1_MYCTO / P9WKK6 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30 from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
ACEA_MYCTU / P9WKK7 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WKK7 isocitrate lyase (EC 4.1.3.1) from Mycobacterium tuberculosis
P9WKK7 isocitrate lyase subunit (EC 4.1.3.1) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ICL, PEP_mutase, ICL
428 amino acids: PaperBLAST, CDD (Singleton 1)

Mycobacterium tuberculosis

ACEA1_MYCTE / H8EVV4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
ACEA1_MYCBO / P0A5H4 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; EC 4.1.3.1 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
ACEA1_MYCTO / P9WKK6 Isocitrate lyase 1; ICL1; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30 from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
ACEA_MYCTU / P9WKK7 Isocitrate lyase; ICL; Isocitrase; Isocitratase; EC 4.1.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P9WKK7 isocitrate lyase (EC 4.1.3.1) from Mycobacterium tuberculosis
P9WKK7 isocitrate lyase subunit (EC 4.1.3.1) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ICL, PEP_mutase, ICL
428 amino acids: PaperBLAST, CDD (Singleton 1)

ACEA2_MYCTE / H8F3R6 Isocitrate lyase 2; ICL2; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; EC 4.1.3.1; EC 4.1.3.30 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
ACEA2_MYCTO / Q8VJU4 Isocitrate lyase 2; ICL2; Isocitrase; Isocitratase; EC 4.1.3.1 from Mycobacterium tuberculosis (strain CDC 1551 / Oshkosh)
PFams: ICL, PEP_mutase, ICL
766 amino acids: PaperBLAST, CDD (Cluster 1)

Neurospora crassa

ACEA_NEUCR / P28299 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CBS 708.71 / DSM 1257 / FGSC 987)
PFams: ICL, PEP_mutase
548 amino acids: PaperBLAST, CDD (Cluster 1)

Pseudomonas fluorescens

Pf6N2E2_6061 Methylisocitrate lyase (EC 4.1.3.30) from Pseudomonas fluorescens FW300-N2E2
PFams: PEP_mutase, ICL
294 amino acids: PaperBLAST, CDD (Cluster 2)

Saccharomyces cerevisiae

ACEA_YEAST / P28240 Isocitrate lyase; ICL; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ICL, PEP_mutase
557 amino acids: PaperBLAST, CDD (Cluster 1)

ACEB_YEAST / Q12031 Mitochondrial 2-methylisocitrate lyase; Methylisocitrate lyase; EC 4.1.3.30 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ICL, PEP_mutase
575 amino acids: PaperBLAST, CDD (Cluster 1)

Salmonella typhimurium

PRPB_SALTY / Q56062 2-methylisocitrate lyase; 2-MIC; MICL; (2R,3S)-2-methylisocitrate lyase; EC 4.1.3.30 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
Q56062 2-methylisocitrate lyase subunit (EC 4.1.3.30) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: PEP_mutase, ICL
295 amino acids: PaperBLAST, CDD (Cluster 2)

Schizosaccharomyces pombe

ACEB_SCHPO / Q9P6J1 Mitochondrial 2-methylisocitrate lyase; Methylisocitrate lyase; EC 4.1.3.30 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: ICL, PEP_mutase
518 amino acids: PaperBLAST, CDD (Cluster 1)

Shewanella oneidensis

PRPB_SHEON / Q8EJW1 2-methylisocitrate lyase; 2-MIC; MICL; (2R,3S)-2-methylisocitrate lyase; EC 4.1.3.30 from Shewanella oneidensis (strain MR-1)
PFams: PEP_mutase, ICL
292 amino acids: PaperBLAST, CDD (Cluster 2)

Toxoplasma gondii

Q2L8W6 Methylisocitrate lyase (EC 4.1.3.30) from Toxoplasma gondii
PFams: PEP_mutase, ICL
369 amino acids: PaperBLAST, CDD (Cluster 2)

Yarrowia lipolytica

ACEA_YARLI / P41555 Isocitrate lyase; ICL; Isocitrase; Isocitratase; Methylisocitrate lyase; MICA; Threo-D(S)-isocitrate glyoxylate-lyase; EC 4.1.3.1; EC 4.1.3.30 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
PFams: ICL, PEP_mutase
540 amino acids: PaperBLAST, CDD (Cluster 1)

ACEB_YARLI / Q6BZP5 2-methylisocitrate lyase, mitochondrial; EC 4.1.3.30 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
PFams: ICL, PEP_mutase
565 amino acids: PaperBLAST, CDD (Cluster 1)