Other Characterized Proteins Similar to DKDP-aldolase

GapMind for catabolism of small carbon sources

Other Characterized Proteins Similar to DKDP-aldolase

Finding the characterized proteins for DKDP-aldolase (2-dehydro-3-deoxy-D-arabinonate aldolase) in D-xylose catabolism

Or see clustering for step DKDP-aldolase

Or see all steps for D-xylose catabolism

Or cluster curated proteins matching a keyword

Definition of DKDP-aldolase

Curated proteins or TIGRFams with EC 4.1.2.28
Ignore hits to items matching 4.1.2.55 when looking for 'other' hits
Comment: A number of EC 4.1.2.55 enzymes are similar but are promiscuous and are likely to have this activity as well. This includes Q97U28 which is nearly identical to the promiscuous KDGA_SACSO (O54288), but is not annotated with this activity.

Fetched 3 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 4 other characterized sequences. (Found 7 hits including self hits.)

Removing ignored items reduces this to 1 close sequences.

Close sequences

(Sequences that are similar to these will not be high-confidence candidates for DKDP-aldolase.)

KDGA_THETE / Q704D1 2-dehydro-3-deoxy-D-gluconate/2-dehydro-3-deoxy-phosphogluconate aldolase; KD(P)G aldolase; EC 4.1.2.14; EC 4.1.2.51 from Thermoproteus tenax
Q704D1 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14) from Thermoproteus tenax
PFams: DHDPS
306 amino acids: PaperBLAST, CDD, SwissProt::Q704D1
45% identical to

O54288 KDG-aldolase subunit (EC 4.1.2.28; EC 4.1.2.18; EC 4.1.2.51) from Saccharolobus solfataricus
KDGA_SACSO / O54288 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Saccharolobus solfataricus (Sulfolobus solfataricus)
O54288 2-dehydro-3-deoxy-phosphogluconate aldolase (EC 4.1.2.14); 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Saccharolobus solfataricus
PFams: DHDPS
294 amino acids: PaperBLAST, CDD

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for DKDP-aldolase.)

KDGA_SACS2 / Q97U28 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Q97U28 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Saccharolobus solfataricus
PFams: DHDPS
308 amino acids: PaperBLAST, CDD, BRENDA::Q97U28
100% identical to

KDGA_SULTO / F9VPG1 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
F9VPG1 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Sulfurisphaera tokodaii
PFams: DHDPS
290 amino acids: PaperBLAST, CDD, SwissProt::F9VPG1
54% identical to

KDGA_SULAC / Q4JC35 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6-phosphogalactonate aldolase; EC 4.1.2.55 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Q4JC35 2-dehydro-3-deoxy-phosphogluconate/2-dehydro-3-deoxy-6 phosphogalactonate aldolase (EC 4.1.2.55) from Sulfolobus acidocaldarius
PFams: DHDPS
288 amino acids: PaperBLAST, CDD, BRENDA::Q4JC35
50% identical to