Other Characterized Proteins Similar to glcB

Finding the characterized proteins for glcB (malate synthase) in D-xylose catabolism

Or see clustering for step glcB

Or see all steps for D-xylose catabolism

Or cluster curated proteins matching a keyword

Definition of glcB

• Curated proteins or TIGRFams with EC 2.3.3.9
• Ignore hits to items matching 4.1.3.24 when looking for 'other' hits
• Comment: Besides the standard enzyme, there's an archaeal enzyme that is sometimes annotated as EC 4.1.3.24, but that only includes the formation of malyl-CoA, not the cleavage to malate.

Fetched 22 sequences

Running ublast to find other characterized proteins with 40% identity and 70% coverage

Found hits to 1 other characterized sequences. (Found 23 hits including self hits.)

Removing ignored items reduces this to 0 close sequences.

Close but ignored sequences

(Sequences that are similar to these will still be high-confidence candidates for glcB.)

AMASY_HALMA / Q5V0X0 Apparent malate synthase; (3S)-malyl-CoA thioesterase; (S)-malyl-CoA lyase; EC 3.1.2.30; EC 4.1.3.24 from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (Halobacterium marismortui)
Q5V0X0 archaeal malate synthase (EC 4.1.3.24) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809)
PFams: HpcH_HpaI
435 amino acids: PaperBLAST, CDD, SwissProt::Q5V0X0
81% identical to

ACEB_HALVD / D4GTL2 Malate synthase; MSH; EC 2.3.3.9 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii)
D4GTL2 malate synthase (EC 2.3.3.9) from Haloferax volcanii
PFams: HpcH_HpaI
433 amino acids: PaperBLAST, CDD