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Similarities of Characterized Proteins

Comparing 23 sequences

Query

EAA2_MOUSE / P43006 Excitatory amino acid transporter 2; GLT-1; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2 from Mus musculus (Mouse)
572 amino acids: PaperBLAST, CDD

Other Sequences with Hits

EAA2_RAT / P31596 Excitatory amino acid transporter 2; GLT-1; Sodium-dependent glutamate/aspartate transporter 2; GLUT-R; Solute carrier family 1 member 2 from Rattus norvegicus (Rat)
TC 2.A.23.2.2 / P31596 Glutamate/aspartate:Na+ symporter, GLT1; GLUT-R; EAAT2. Interacts directly with the Na+, K+-ATPase (TC #3.A.3.1) (Rose et al., 2009). Cotransports glutamic acid with three Na+ followed by countertransport of K+ (Teichman et al., 2009). The C-terminal 74aa domain regulates transport activity (Leinenweber et al., 2011). Hippocampal glutamate transporter 1 (GLT-1) levels parallel memory training (Heo et al., 2011). GLT-1 is regulated by MAGI-1 from Rattus norvegicus (Rat)
573 amino acids: PaperBLAST, CDD
98% identical to query, 100% coverage

EAA2_HUMAN / P43004 Excitatory amino acid transporter 2; Glutamate/aspartate transporter II; Sodium-dependent glutamate/aspartate transporter 2; Solute carrier family 1 member 2 from Homo sapiens (Human)
TC 2.A.23.2.7 / P43004 Excitatory amino acid transporter 2, EAAT2 (Glutamate/aspartate transporter II) (Sodium-dependent glutamate/aspartate transporter 2) (Solute carrier family 1 member 2) from Homo sapiens
574 amino acids: PaperBLAST, CDD
95% identical to query, 100% coverage

EAA3_RAT / P51907 Excitatory amino acid transporter 3; Excitatory amino-acid carrier 1; Sodium-dependent glutamate/aspartate transporter 3; Solute carrier family 1 member 1 from Rattus norvegicus (Rat)
523 amino acids: PaperBLAST, CDD
59% identical to query, 74% coverage

TC 2.A.23.2.10 / Q10901 Excitatory amino acid transporter (Sodium-dependent glutamate/aspartate transporter), Gkt-1 of 503 aas and 9 - 11 TMSs from Caenorhabditis elegans
503 amino acids: PaperBLAST, CDD
57% identical to query, 90% coverage

EAA3_MOUSE / P51906 Excitatory amino acid transporter 3; Excitatory amino-acid carrier 1; Sodium-dependent glutamate/aspartate transporter 3; Solute carrier family 1 member 1 from Mus musculus (Mouse)
523 amino acids: PaperBLAST, CDD
55% identical to query, 79% coverage

EAA3_RABIT / P31597 Excitatory amino acid transporter 3; Excitatory amino-acid carrier 1; Sodium-dependent glutamate/aspartate transporter 3; Solute carrier family 1 member 1 from Oryctolagus cuniculus (Rabbit)
524 amino acids: PaperBLAST, CDD
54% identical to query, 81% coverage

EAA1_RAT / P24942 Excitatory amino acid transporter 1; Glial glutamate transporter; Sodium-dependent glutamate/aspartate transporter 1; GLAST; GLAST-1; Solute carrier family 1 member 3 from Rattus norvegicus (Rat)
TC 2.A.23.2.1 / P24942 Glutamate/aspartate:Na+ symporter, GLAST or EAAT1, Structural rearrangements have been probed by Leighton et al., 2006). EAAT1 interacts directly with the Na+, K+-ATPase (TC #3.A.3.1) (Rose et al., 2009). CEAT1 couples glutamate uptake to the symport of 3 Na+ and 1 H+ followed by the antiport of 1 K+. It can function as an uncoupled anion, water and/or urea channel (Vandenberg et al., 2011). Large collective motions regulate the functional properties of EAAT1 trimers from Rattus norvegicus (Rat)
RF|NP_062098.1 excitatory amino acid transporter 1 from Rattus norvegicus
543 amino acids: PaperBLAST, CDD
54% identical to query, 85% coverage

EAA1_HUMAN / P43003 Excitatory amino acid transporter 1; Sodium-dependent glutamate/aspartate transporter 1; GLAST-1; Solute carrier family 1 member 3 from Homo sapiens (Human)
TC 2.A.23.2.6 / P43003 Excitatory amino acid transporter 1 (EAAT1) (Sodium-dependent glutamate/aspartate transporter 1) (GLAST-1) (Solute carrier family 1 member 3) from Homo sapiens
542 amino acids: PaperBLAST, CDD
54% identical to query, 85% coverage

EAA1_MOUSE / P56564 Excitatory amino acid transporter 1; Glial high affinity glutamate transporter; High-affinity neuronal glutamate transporter; GluT-1; Sodium-dependent glutamate/aspartate transporter 1; GLAST-1; Solute carrier family 1 member 3 from Mus musculus (Mouse)
543 amino acids: PaperBLAST, CDD
54% identical to query, 85% coverage

EAA1_BOVIN / P46411 Excitatory amino acid transporter 1; Sodium-dependent glutamate/aspartate transporter 1; GLAST-1; Solute carrier family 1 member 3 from Bos taurus (Bovine)
542 amino acids: PaperBLAST, CDD
53% identical to query, 85% coverage

EAA3_HUMAN / P43005 Excitatory amino acid transporter 3; Excitatory amino-acid carrier 1; Neuronal and epithelial glutamate transporter; Sodium-dependent glutamate/aspartate transporter 3; Solute carrier family 1 member 1 from Homo sapiens (Human)
TC 2.A.23.2.3 / P43005 Glutamate/aspartate/cysteine:Na+ symporter, EAAC1; EAAT3, SLC1A1 (Li+ can replace Na+; EAAC1 also mediates glutamate-independent anion conductance.) Cotransports glutamic acid with three Na+ followed by countertransport of K+(Teichman et al., 2009). The 50 residue 4B-4C loop (following TMS4) binds Na+ (Koch et al., 2007). (The dicarboxylic aminoaciduria protein in humans; NP_004161; Bröer, 2008a; 2008b). Neutralizing aspartate 83 modifies substrate translocation from Homo sapiens (Human)
524 amino acids: PaperBLAST, CDD
53% identical to query, 86% coverage

EAA1_AMBTI / O57321 Excitatory amino acid transporter 1; SEAAT1; Sodium-dependent glutamate/aspartate transporter; GLAST from Ambystoma tigrinum (Eastern tiger salamander)
543 amino acids: PaperBLAST, CDD
52% identical to query, 85% coverage

TC 2.A.23.2.11 / B0W0K4 EAAT homologue, a glutamate/aspartate preferring transporter of 483 aas from Culex quinquefasciatus
483 amino acids: PaperBLAST, CDD
47% identical to query, 82% coverage

GLT_PYRHO / O59010 Glutamate transporter homolog; Glt(Ph); Sodium-aspartate symporter Glt(Ph); Sodium-dependent aspartate transporter from Pyrococcus horikoshii (strain ATCC 700860 / DSM 12428 / JCM 9974 / NBRC 100139 / OT-3)
TC 2.A.23.1.5 / O59010 Archaeal aspartate transporter, Gltph (GltPh) (3-D structure known; 3V8F and 3V8G) (Boudker et al., 2007; Yernool et al., 2004). Cotransports aspartate with 2 Na+ (Ryan et al., 2009) or 3 Na+ (Groeneveld and Slotboom, 2010) or 1Na+ plus 1 H+ plus 1 K+ from Pyrococcus horikoshii
425 amino acids: PaperBLAST, CDD
32% identical to query, 78% coverage

A1S570 SubName: Full=Sodium:dicarboxylate symporter {ECO:0000313|EMBL:ABL99526.1};
437 amino acids: PaperBLAST, CDD
32% identical to query, 78% coverage

b4077 glutamate/aspartate : H+ symporter GltP from Escherichia coli K-12 substr. MG1655
GLTP_ECOLI / P21345 Proton/glutamate-aspartate symporter; Glutamate-aspartate carrier protein; Proton-glutamate-aspartate transport protein from Escherichia coli (strain K12)
TC 2.A.23.1.1 / P21345 Glutamate/aspartate:H+ symporter, GltP or GltT; has 8 TMSs with 2 re-entrant loops as for GltPh (TC# 2.A.23.1.5) from Escherichia coli
437 amino acids: PaperBLAST, CDD
28% identical to query, 77% coverage

GLTT_GEOSE / P24943 Proton/sodium-glutamate symport protein; Glutamate-aspartate carrier protein from Geobacillus stearothermophilus (Bacillus stearothermophilus)
TC 2.A.23.1.2 / P24943 Glutamate/aspartate:Na+ + H+ symporter from Bacillus stearothermophilus
GI|143000 proton/sodium-glutamate symport protein GltT from Geobacillus stearothermophilus
421 amino acids: PaperBLAST, CDD
27% identical to query, 75% coverage

GLTT_BACCA / P24944 Proton/sodium-glutamate symport protein; Glutamate-aspartate carrier protein from Bacillus caldotenax
GI|143002 proton/sodium-glutamate symport protein GltT from Bacillus caldotenax
421 amino acids: PaperBLAST, CDD
27% identical to query, 75% coverage

A0A0C4Y5S4 SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AJG18233.1};
436 amino acids: PaperBLAST, CDD
26% identical to query, 72% coverage

A0A0N9WTL5 SubName: Full=Amino acid:proton symporter {ECO:0000313|EMBL:ALI05583.1};
431 amino acids: PaperBLAST, CDD
26% identical to query, 71% coverage

b3528 C4 dicarboxylate/orotate:H+ symporter from Escherichia coli K-12 substr. MG1655
P0A830 C4 dicarboxylate/orotate:H+ symporter from Escherichia coli (strain K12)
DCTA_ECOLI / P0A830 Aerobic C4-dicarboxylate transport protein from Escherichia coli (strain K12)
TC 2.A.23.1.7 / P0A830 Aerobic dicarboxylate transporter, DctA. Interacts with the DcuS sensor kinase from Escherichia coli (strain K12)
GB|AAC76553.1 aerobic C4-dicarboxylate transport protein from Escherichia coli
428 amino acids: PaperBLAST, CDD
26% identical to query, 78% coverage

Other Sequences without Hits

GLTP_BACSU / P39817 Proton/glutamate-aspartate symporter; Proton/glutamate symport protein from Bacillus subtilis (strain 168)
414 amino acids: PaperBLAST, CDD