PaperBLAST – Find papers about a protein or its homologs


Similarities of Characterized Proteins

Comparing 5 sequences


TC 2.A.1.1.71 / B1PLM1 Hexose (glucose) transporter, GT4 (D2) (almost identical to 2.A.1.1.16) from Leishmania mexicana
627 amino acids: PaperBLAST, CDD

Other Sequences with Hits

TC 2.A.1.1.78 / O61060 The glucose transporter, LmGT3 (homologous to LmGT2 (1.A.1.1.75)). Two threonine residues located in the hydrophilic loops connecting TMSs 3 & 4 and 7 & 8 of GT3 prevent transport of D-ribose. Changing these two residues to alanine (as in GT2) allows transport of ribose. Thus, loops 3-4 and 7-8 partially determine substrate specificity from Leishmania mexicana
566 amino acids: PaperBLAST, CDD
44% identical to query, 84% coverage

TC 2.A.1.1.77 / O61059 The D-glucose/D-ribose transporter, LmGT2 (Most similar to 1.A.1.1.18) from Leishmania mexicana
567 amino acids: PaperBLAST, CDD
43% identical to query, 87% coverage

TC 2.A.1.1.76 / O76486 Glucose transporter, GT1. GT1, 2, and 3 are homologues. GT2 and GT3 transport ribose as well as glucose at different rates. GT3 transports ribose with 6-fold lower efficiency due to two threonines in GT3 that are alanines in GT2. They are in two loops between TMSs 3, 4, and 7, 8 (Naula et al., 2010). GT1 is expressed in the flagellar membrane and may be both a glucose transporter and sensor, allowing the parasites to enter the stationary phase when they deplete glucose although in the absence of the sensor, they lose viability from Leishmania mexicana
610 amino acids: PaperBLAST, CDD
43% identical to query, 87% coverage

TC 2.A.1.1.18 / Q06222 Glucose/mannose/fructose transporter and high affinity sensor, Snf3p (regulates glucose transport via other systems) from Trypanosoma brucei brucei
529 amino acids: PaperBLAST, CDD
37% identical to query, 85% coverage

Other Sequences without Hits