Alignments for a candidate for leuA in Thauera aminoaromatica S2

Align 2-isopropylmalate synthase; Alpha-IPM synthase; Alpha-isopropylmalate synthase; EC 2.3.3.13 (characterized)
to candidate WP_004324818.1 C665_RS17575 2-isopropylmalate synthase

Query= SwissProt::P42455
         (616 letters)



>NCBI__GCF_000310185.1:WP_004324818.1
          Length = 570

 Score =  591 bits (1524), Expect = e-173
 Identities = 318/576 (55%), Positives = 395/576 (68%), Gaps = 35/576 (6%)

Query: 37  PVNRYMPFEVEVEDISLPDRTWPDKKITVAPQWCAVDLRDGNQALIDPMSPERKRRMFEL 96
           P  +Y PF      I+L DR WP+  I  AP W + DLRDGNQAL +PM+ ERK RMF  
Sbjct: 6   PAAKYRPFA----PIALADRQWPNTLIERAPIWMSTDLRDGNQALFEPMNVERKMRMFRT 61

Query: 97  LVQMGFKEIEVGFPSASQTDFDFVREIIEKGMIPDDVTIQVLVQAREHLIRRTFEACEGA 156
           + ++GFKEIEVGFPSASQTDFDFVR +IE G IP DVTIQVL QARE LIRRT E+  GA
Sbjct: 62  VCEIGFKEIEVGFPSASQTDFDFVRALIEGGHIPADVTIQVLTQAREDLIRRTMESVRGA 121

Query: 157 KNVIVHFYNSTSILQRNVVFRMDKVQVKKLATDAAELIKTIAQDYPD---TNWRWQYSPE 213
              I+H YN+TS   R +VF M+K QV  LA  A  LIK I  +      T  R +YSPE
Sbjct: 122 PRAIIHVYNATSPTFRELVFGMEKPQVLALAVSAVRLIKQIGAEMEKECGTEIRLEYSPE 181

Query: 214 SFTGTEVEYAKEVVDAVVEVMDPTPENPMIINLPSTVEMITPNVYADSIEWMHRNLNRRD 273
           +F+ TE+++A+EV DAV      TPEN +I+NLP+TVE+ TPNVYAD +EWMHRNL RRD
Sbjct: 182 TFSATELDFAREVCDAVTAEWGATPENKVILNLPATVEVATPNVYADQVEWMHRNLARRD 241

Query: 274 SIILSLHPHNDRGTGVGAAELGYMAGADRIEGCLFGNGERTGNVCLVTLALNMLTQGVDP 333
           S++LSLHPHNDRG+GV AAELG MAGADR+EGCLFGNGERTGNV +VTLALNM TQGV P
Sbjct: 242 SVVLSLHPHNDRGSGVAAAELGLMAGADRVEGCLFGNGERTGNVDIVTLALNMYTQGVSP 301

Query: 334 QLDFTDIRQIRSTVEYCNQLRVPERHPYGGDLVFTAFSGSHQDAVNKGLDAMAAKVQPGA 393
            LDF+DI  +  TVEYCNQL +  RHPY GDLVFTAFSGSHQDA+ KG  A  A  QP  
Sbjct: 302 GLDFSDINAVARTVEYCNQLPIHPRHPYVGDLVFTAFSGSHQDAIKKGFAAQKAG-QP-- 358

Query: 394 SSTEVSWEQLRDTEWEVPYLPIDPKDVGRDYEAVIRVNSQSGKGGVAYIMKTDHGLQIPR 453
                         W VPYLPIDP DVGR Y++VIRVNSQSGKGG+AY+++T++G+ +PR
Sbjct: 359 --------------WNVPYLPIDPADVGRSYDSVIRVNSQSGKGGIAYLLETEYGIVMPR 404

Query: 454 SMQVEFSTVVQNVTDAEGGEVNSKAMWDIFATEYLERTAPVEQIALRVENAQTENEDA-S 512
            +QVEFS  VQ VTDA GGE+++ A+WD+F + YL+   PV      VE+   E+  A  
Sbjct: 405 RLQVEFSREVQQVTDASGGEMSAAAIWDLFRSTYLDNVEPVRY----VEHHLFEHGAAQG 460

Query: 513 ITAELIHNGKDVTVDGRGNGPLAAYANALEKLGIDVEIQEYNQHA---RTSGDDAEAAAY 569
           I   +   G    + G GNGP+ A  +AL   GIDV+++ + + +      G +A+A A+
Sbjct: 461 IRLVVEFGGTRHLLVGEGNGPIDAAIHALRGAGIDVQVRSFEERSVAPSEDGGNAQACAF 520

Query: 570 V-LAEVNGR--KVWGVGIAGSITYASLKAVTSAVNR 602
           + L E  G+    +GVGI  +I  AS++A+ S VNR
Sbjct: 521 LELTEAGGQGGDRYGVGIDANIVTASIRAILSGVNR 556


Lambda     K      H
   0.316    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 972
Number of extensions: 42
Number of successful extensions: 5
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 616
Length of database: 570
Length adjustment: 37
Effective length of query: 579
Effective length of database: 533
Effective search space:   308607
Effective search space used:   308607
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 53 (25.0 bits)

Align candidate WP_004324818.1 C665_RS17575 (2-isopropylmalate synthase)
to HMM TIGR00970 (leuA: 2-isopropylmalate synthase (EC 2.3.3.13))

Software error:

../bin/blast/fastacmd -i /tmp/list.20948.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.20948.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.

For help, please send mail to the webmaster (help@microbesonline.org), giving this error message and the time and date of the error.