Alignments for a candidate for serA in Methanosarcina acetivorans C2A

Align D-3-phosphoglycerate dehydrogenase; EC 1.1.1.95 (characterized, see rationale)
to candidate WP_011020641.1 MA_RS03105 phosphoglycerate dehydrogenase

Query= uniprot:Q6LWW6
         (523 letters)



>NCBI__GCF_000007345.1:WP_011020641.1
          Length = 523

 Score =  484 bits (1247), Expect = e-141
 Identities = 253/522 (48%), Positives = 358/522 (68%), Gaps = 1/522 (0%)

Query: 3   KILITDPLHESAVEILKQAGEVEVATGLTVEELKLKIKDVDALVIRSGTTATREIIEASE 62
           K+L++D L    +EILK+   V+V TGL+ +EL  KI + DALVIRSGT  T+ +IEA++
Sbjct: 2   KVLVSDSLSNEGLEILKEHFTVDVNTGLSEDELVEKIGEYDALVIRSGTQVTQRVIEAAD 61

Query: 63  NLKVIARAGVGVDNVDLDAATEKGIVVVNAPDASSISVAELLFGMMLAAARNIPQATASI 122
           NLK++ RAGVGVDNVD+DAAT+KGI+V NAP+ + IS AE   GMM+A +RNIPQA AS+
Sbjct: 62  NLKIVGRAGVGVDNVDVDAATKKGIIVANAPEGNMISAAEHTIGMMMAMSRNIPQANASL 121

Query: 123 KSGKWDRKSFKGMEIYGKTLGIVGLGRIGQQVAKRAQAFGMTIVAYDPYIPEDVASELGI 182
           K  +W R  F G+E+ GKTLGI+GLGRIG +VAKRA    M ++ YDP+I E  A ELG+
Sbjct: 122 KGREWKRNKFMGVEVKGKTLGIIGLGRIGSEVAKRASGLEMNLMGYDPFISEKRAMELGV 181

Query: 183 KLLTVDELCTVSDFITLHVPLTPKTKHMIGKEQIALMKSNMVIMNCARGGLIDEAALYDA 242
           KL TV+E+   +D+IT+H PL  +T++++  EQ  LMKS + I+NCARGG+I+EAAL  A
Sbjct: 182 KLATVNEISKEADYITVHTPLIKETRNILDDEQFDLMKSGVRILNCARGGIINEAALVRA 241

Query: 243 LNSGKIKAAALDVFEQEPPKESPLLTLNNLIGTPHQGASTEEAQLSAGTIVAEQTVKILK 302
           L SGK+  AALDVF +EPP  SPLL  +N+I TPH GAST+EAQ++    +A++ V +L 
Sbjct: 242 LESGKVGGAALDVFVEEPPFGSPLLNFDNVIVTPHLGASTQEAQVNVAIDIAKEVVSVLT 301

Query: 303 GESAENVVNLPMVPTEKMKKLKPYMVLAEKMGSMAIQYLDNSIELLEITYMGGLAKEKTE 362
           G  A+N +N+P V  E M  L PY+ LAE MG +A Q +D++ E +EI Y G ++ + T 
Sbjct: 302 GGLAKNAINIPSVKPEAMAVLAPYIRLAELMGKIAGQLVDSNYEKVEIGYNGEISGKDTR 361

Query: 363 ILKRSFLKGILAPILLAGVNLVNAPVIAKSRNIKIAEG-TMSESDYGNSIKISAKGENDE 421
            L  S LKG+L   L AGVN VNAP +AKSR I + E  + S  +Y +++ I        
Sbjct: 362 PLTVSALKGLLEMALGAGVNYVNAPALAKSRQIAVVESKSESAEEYSSTVSIKLSSGETA 421

Query: 422 ISIIGSIEHNEVVFREINGYRMDIKPEGTICIIKHIDRPGMVGKVGVLLGEHGINIAGMQ 481
             + G++  +E     I+  R+DI P G +   KHI++P ++G   ++LG++ INI+GMQ
Sbjct: 422 KLVAGTVVGDEPKIVSIDEDRVDIFPAGRMIFAKHINKPNVIGPCCMVLGKNNINISGMQ 481

Query: 482 VGRREPGGHSIMFLDIDHMISDEVLDEIRKMENVRAAKSINI 523
           VGR E GG ++M L++D  +SD +LDE+R++  +  AK + +
Sbjct: 482 VGRSEVGGVTMMVLNVDTDVSDAILDEVRQVPGILNAKLVTL 523


Lambda     K      H
   0.316    0.134    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 747
Number of extensions: 23
Number of successful extensions: 3
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 523
Length of database: 523
Length adjustment: 35
Effective length of query: 488
Effective length of database: 488
Effective search space:   238144
Effective search space used:   238144
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 52 (24.6 bits)

Align candidate WP_011020641.1 MA_RS03105 (phosphoglycerate dehydrogenase)
to HMM TIGR01327 (serA: phosphoglycerate dehydrogenase (EC 1.1.1.95))

Software error:

../bin/blast/fastacmd -i /tmp/list.2626.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.2626.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.

For help, please send mail to the webmaster (help@microbesonline.org), giving this error message and the time and date of the error.