| Pathway | Step | Score | Similar to | Id. | Cov. | Bits | Other hit | Other id. | Other bits |
|---|
| L-proline catabolism | opuBA | med | BusAA, component of Uptake system for glycine-betaine (high affinity) and proline (low affinity) (OpuAA-OpuABC) or BusAA-ABC of Lactococcus lactis). BusAA, the ATPase subunit, has a C-terminal tandem cystathionine β-synthase (CBS) domain which is the cytoplasmic K+ sensor for osmotic stress (osmotic strength)while the BusABC subunit has the membrane and receptor domains fused to each other (Biemans-Oldehinkel et al., 2006; Mahmood et al., 2006; Gul et al. 2012). An N-terminal amphipathic α-helix of OpuA is necessary for high activity but is not critical for biogenesis or the ionic regulation of transport (characterized) | 53% | 99% | 412.9 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-proline catabolism | proV | med | glycine betaine/l-proline transport atp-binding protein prov (characterized) | 52% | 99% | 389.8 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-histidine catabolism | hutV | med | ABC transporter for L-Histidine, ATPase component (characterized) | 57% | 95% | 309.7 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-proline catabolism | hutV | med | HutV aka HISV aka R02702 aka SMC00670, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine (characterized) | 55% | 95% | 306.6 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-histidine catabolism | Ac3H11_2560 | med | ABC transporter for L-Histidine, ATPase component (characterized) | 41% | 82% | 164.1 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-asparagine catabolism | aatP | med | ABC transporter for L-Asparagine and possibly other L-amino acids, putative ATPase component (characterized) | 40% | 86% | 154.5 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-aspartate catabolism | aatP | med | ABC transporter for L-Asparagine and possibly other L-amino acids, putative ATPase component (characterized) | 40% | 86% | 154.5 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-glutamate catabolism | gltL | med | ABC transporter for L-asparagine and L-glutamate, ATPase component (characterized) | 40% | 86% | 154.5 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| putrescine catabolism | potA | lo | Spermidine/putrescine import ATP-binding protein PotA, component of The spermidine/putrescine uptake porter, PotABCD (characterized) | 41% | 65% | 194.5 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-cellobiose catabolism | gtsD | lo | Sugar ABC transporter ATP-binding protein (characterized, see rationale) | 41% | 66% | 172.6 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-glucose catabolism | gtsD | lo | Sugar ABC transporter ATP-binding protein (characterized, see rationale) | 41% | 66% | 172.6 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| lactose catabolism | gtsD | lo | Sugar ABC transporter ATP-binding protein (characterized, see rationale) | 41% | 66% | 172.6 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-maltose catabolism | gtsD | lo | Sugar ABC transporter ATP-binding protein (characterized, see rationale) | 41% | 66% | 172.6 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| sucrose catabolism | gtsD | lo | Sugar ABC transporter ATP-binding protein (characterized, see rationale) | 41% | 66% | 172.6 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| trehalose catabolism | gtsD | lo | Sugar ABC transporter ATP-binding protein (characterized, see rationale) | 41% | 66% | 172.6 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-galactose catabolism | PfGW456L13_1897 | lo | ABC transporter for D-Galactose and D-Glucose, ATPase component (characterized) | 33% | 90% | 171 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-arabinose catabolism | xacJ | lo | Xylose/arabinose import ATP-binding protein XacJ; EC 7.5.2.13 (characterized, see rationale) | 36% | 63% | 168.3 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-arabinose catabolism | xacK | lo | Xylose/arabinose import ATP-binding protein XacK; EC 7.5.2.13 (characterized, see rationale) | 39% | 57% | 164.5 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-asparagine catabolism | glnQ | lo | Glutamine ABC transporter ATP-binding protein, component of Glutamine transporter, GlnQP. Takes up glutamine, asparagine and glutamate which compete for each other for binding both substrate and the transmembrane protein constituent of the system (Fulyani et al. 2015). Tandem substrate binding domains (SBDs) differ in substrate specificity and affinity, allowing cells to efficiently accumulate different amino acids via a single ABC transporter. Analysis revealed the roles of individual residues in determining the substrate affinity (characterized) | 36% | 100% | 164.1 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-histidine catabolism | PA5503 | lo | Methionine import ATP-binding protein MetN 2, component of L-Histidine uptake porter, MetIQN (characterized) | 39% | 72% | 164.1 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-maltose catabolism | musK | lo | ABC-type maltose transporter (EC 7.5.2.1) (characterized) | 38% | 58% | 162.5 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-glucosamine (chitosamine) catabolism | SM_b21216 | lo | ABC transporter for D-Glucosamine, ATPase component (characterized) | 38% | 63% | 161.8 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| trehalose catabolism | treV | lo | TreV, component of Trehalose porter (characterized) | 34% | 88% | 161.8 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-maltose catabolism | thuK | lo | ThuK aka RB0314 aka SMB20328, component of Trehalose/maltose/sucrose porter (trehalose inducible) (characterized) | 39% | 64% | 159.1 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| sucrose catabolism | thuK | lo | ThuK aka RB0314 aka SMB20328, component of Trehalose/maltose/sucrose porter (trehalose inducible) (characterized) | 39% | 64% | 159.1 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| trehalose catabolism | thuK | lo | ThuK aka RB0314 aka SMB20328, component of Trehalose/maltose/sucrose porter (trehalose inducible) (characterized) | 39% | 64% | 159.1 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-maltose catabolism | aglK | lo | ABC transporter for D-Maltose and D-Trehalose, ATPase component (characterized) | 32% | 80% | 158.3 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| sucrose catabolism | aglK | lo | ABC transporter for D-Maltose and D-Trehalose, ATPase component (characterized) | 32% | 80% | 158.3 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| trehalose catabolism | aglK | lo | ABC transporter for D-Maltose and D-Trehalose, ATPase component (characterized) | 32% | 80% | 158.3 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-asparagine catabolism | bztD | lo | BztD, component of Glutamate/glutamine/aspartate/asparagine porter (characterized) | 34% | 90% | 152.9 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-aspartate catabolism | bztD | lo | BztD, component of Glutamate/glutamine/aspartate/asparagine porter (characterized) | 34% | 90% | 152.9 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-alanine catabolism | Pf6N2E2_5405 | lo | ABC transporter for D-Alanine, ATPase component (characterized) | 38% | 88% | 151.4 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| L-lysine catabolism | hisP | lo | Amino-acid ABC transporter, ATP-binding protein (characterized, see rationale) | 36% | 86% | 147.1 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |
| D-glucosamine (chitosamine) catabolism | AO353_21725 | lo | ABC transporter for D-Glucosamine, putative ATPase component (characterized) | 36% | 87% | 144.4 | OtaA, component of The salt-induced glycine betaine OtaABC transporter | 71% | 616.3 |