Alignments for a candidate for leuA in Heliomicrobium modesticaldum Ice1; ATCC 51547

Align 2-isopropylmalate synthase (EC 2.3.3.13) (characterized)
to candidate WP_012282601.1 HM1_RS06890 2-isopropylmalate synthase

Query= BRENDA::Q9JZG1
         (517 letters)



>NCBI__GCF_000019165.1:WP_012282601.1
          Length = 512

 Score =  542 bits (1396), Expect = e-158
 Identities = 282/509 (55%), Positives = 370/509 (72%), Gaps = 3/509 (0%)

Query: 4   TNRVIIFDTTLRDGEQSPGAAMTKEEKIRVARQLEKLGVDIIEAGFAAASPGDFEAVNAI 63
           + RV+IFDTTLRDGEQSPG ++   EK+ +A+QL +LGVD+IEAGF  ASPGDFEAV A+
Sbjct: 2   SKRVVIFDTTLRDGEQSPGVSLNLHEKLEIAQQLARLGVDVIEAGFPIASPGDFEAVKAV 61

Query: 64  AKTITKSTVCSLSRAIERDIRQAGEAVAPAPKKRIHTFIATSPIHMEYKLKMKPKQVIEA 123
           A+ +    +C+L+RA  +DI +A EA+  A + RIHTFIATSPIHM++KL+M+P +V++ 
Sbjct: 62  AEQVRGPVICALARANRKDIERAAEALRGAEEARIHTFIATSPIHMQHKLRMEPDKVLDT 121

Query: 124 AVKAVKIAREYTDDVEFSCEDALRSEIDFLAEICGAVIEAGATTINIPDTVGYSIPYKTE 183
           AV AVK+A+ +T +VEFS EDA RS++ FL  I  A IEAGATTINIPDTVGY+ P +  
Sbjct: 122 AVDAVKLAKSFTSNVEFSAEDAFRSDVGFLCRIFSAAIEAGATTINIPDTVGYATPQEFG 181

Query: 184 EFFRELIAKTPNGGKVVWSAHCHNDLGLAVANSLAALKGGARQVECTVNGLGERAGNASV 243
            F + +I  TPN  K + S HCHNDLGLAVAN+LAAL+ GA QVE T+NG+GERAGNAS+
Sbjct: 182 AFIKAIINGTPNIDKAIVSVHCHNDLGLAVANTLAALENGALQVEGTINGIGERAGNASL 241

Query: 244 EEIVMALKVRHDLFGLETGIDTTQIVPSSKLVSTITGYPVQPNKAIVGANAFSHESGIHQ 303
           EE++MAL  R   + LET I+ ++I  +S+LVS +TG  VQPNKAIVG NAF+HESGIHQ
Sbjct: 242 EEVIMALYTRKPFYNLETSINKSEIYRTSRLVSNLTGMLVQPNKAIVGKNAFAHESGIHQ 301

Query: 304 DGVLKHRETYEIMSAESVGWATNRLSLGKLSGRNAFKTKLADLGIELESEEALNAAFARF 363
           DGVLK R TYEIM+ E +G  TN + LGK SGR+AF+ +L +LG  L+ +E L  AFARF
Sbjct: 302 DGVLKERTTYEIMNPEMIGIFTNNIVLGKHSGRHAFRERLKELGYSLD-DEKLTKAFARF 360

Query: 364 KELADKKREIFDEDLHALVSDEMGSMNAESYKFISQKISTETGEEPRADIVFSIKGEEKR 423
           K LAD+KREI DEDL  LV DE+ +   E+Y      I++ T   P A +    + E   
Sbjct: 361 KALADRKREITDEDLVVLVEDELRAF-PEAYSLEYLHITSGTVLVPTATVRLRREEENFE 419

Query: 424 ASATGSGPVDAIFKAIESVAQSGAALQIYSVNAVTQGTESQGETSVRLARGNRVVNGQGA 483
            ++ G GPVDA +KAIE +  +GA L  Y+++A T G +SQGE SV+L R  R   G+G 
Sbjct: 420 EASCGDGPVDAAYKAIEKITGTGARLASYAISATTAGEDSQGEVSVKLEREGRFYTGRGV 479

Query: 484 DTDVLVATAKAYLSALSKLEFSAAKPKAQ 512
           DTD++VA+AKAYL+A++K+ F    PKA+
Sbjct: 480 DTDIIVASAKAYLNAVNKIVFDGL-PKAK 507


Lambda     K      H
   0.313    0.129    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 655
Number of extensions: 21
Number of successful extensions: 3
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 517
Length of database: 512
Length adjustment: 35
Effective length of query: 482
Effective length of database: 477
Effective search space:   229914
Effective search space used:   229914
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 52 (24.6 bits)

Align candidate WP_012282601.1 HM1_RS06890 (2-isopropylmalate synthase)
to HMM TIGR00973 (leuA: 2-isopropylmalate synthase (EC 2.3.3.13))

Software error:

../bin/blast/fastacmd -i /tmp/list.31503.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.31503.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.

For help, please send mail to the webmaster (help@microbesonline.org), giving this error message and the time and date of the error.