GapMind for Amino acid biosynthesis

 

Alignments for a candidate for hisI in Acidithiobacillus ferrooxidans ATCC 23270

Align putative bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase (EC 3.5.4.19; EC 3.6.1.31) (characterized)
to candidate WP_012537569.1 AFE_RS13975 bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE

Query= metacyc::HISTCYCLOPRATPPHOS
         (203 letters)



>NCBI__GCF_000021485.1:WP_012537569.1
          Length = 230

 Score =  149 bits (377), Expect = 3e-41
 Identities = 84/197 (42%), Positives = 115/197 (58%), Gaps = 11/197 (5%)

Query: 16  DGLMPVIVQHAVSGEVLMLGYMNPEALDKTLESGKVTFFSRTKQRLWTKGETSGNFLNVV 75
           DGL+P I Q A SG VLML +MN +AL  TL  G  T++SR++Q LW KGETSG+  ++V
Sbjct: 20  DGLVPAIAQDARSGRVLMLAWMNADALLATLRDGLGTYWSRSRQALWRKGETSGHIQHLV 79

Query: 76  SIAPDCDNDTLLVLANPIGPTCHKGTSSCF--GDTAHQ-W--------LFLYQLEQLLAE 124
            +  DCD DTLL+     GP CH G  +CF  G    Q W          L  L+  L  
Sbjct: 80  DLRLDCDGDTLLLRVIQEGPACHTGEQTCFFLGQPGEQGWQHQAPPPGSILDSLQVTLHN 139

Query: 125 RKSADPETSYTAKLYASGTKRIAQKVGEEGVETALAATVHDRFELTNEASDLMYHLLVLL 184
           R++ADP  SY A+L   G  RI +KVGEE  E  +A   H+   +  EA+DL++HL+V L
Sbjct: 140 RRTADPGQSYVAQLLHGGQDRILKKVGEEATEFVIACKNHESKHIVAEAADLVFHLMVAL 199

Query: 185 QDQGLDLTTVIENLRKR 201
           +++ L +  V+  L +R
Sbjct: 200 EERDLHIDDVLGELARR 216


Lambda     K      H
   0.317    0.132    0.384 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 125
Number of extensions: 4
Number of successful extensions: 2
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 203
Length of database: 230
Length adjustment: 22
Effective length of query: 181
Effective length of database: 208
Effective search space:    37648
Effective search space used:    37648
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 45 (21.9 bits)

Align candidate WP_012537569.1 AFE_RS13975 (bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE)
to HMM TIGR03188 (hisE: phosphoribosyl-ATP diphosphatase (EC 3.6.1.31))

Software error:

../bin/blast/fastacmd -i /tmp/list.2252.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.2252.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.

For help, please send mail to the webmaster (help@microbesonline.org), giving this error message and the time and date of the error.