Align cobalamin-dependent methionine synthase (EC 2.1.1.13) (characterized)
to candidate WP_012852642.1 TCUR_RS11345 methionine synthase
Query= metacyc::G18NG-11090-MONOMER
(1221 letters)
>NCBI__GCF_000024385.1:WP_012852642.1
Length = 1157
Score = 1463 bits (3788), Expect = 0.0
Identities = 758/1202 (63%), Positives = 906/1202 (75%), Gaps = 56/1202 (4%)
Query: 21 ALANHVLIGDGAMGTQLQGFDLDVEKDFLDLEGCNEILNDTRPDVLRQIHRAYFEAGADL 80
AL V++ DGAMGT LQ + ++ DF EGCNEILN TRPD++R +H AY +AG D
Sbjct: 11 ALRERVVVADGAMGTMLQAHNPTLD-DFQGYEGCNEILNVTRPDIVRAVHAAYLDAGVDC 69
Query: 81 VETNTFGCNLPNLADYDIADRCRELAYKGTAVAREVADEMGPGRNGMRRFVVGSLGPGTK 140
VETNTFG NL NL +Y I DR ELA G +AREVAD R+V+GS+GPGTK
Sbjct: 70 VETNTFGANLGNLGEYGITDRIEELAEAGARIAREVADSYSTPERP--RWVIGSIGPGTK 127
Query: 141 LPSLGHAPYADLRGHYKEAALGIIDGGGDAFLIETAQDLLQVKAAVHGVQDAMAELDTFL 200
LP+LGH Y +LR Y+ A G+I GG A L+ET QDLLQVKAA++G + A+AE +
Sbjct: 128 LPTLGHVSYGELRESYRRTAAGLIAGGAHALLVETCQDLLQVKAALNGAKQAVAEAGADV 187
Query: 201 PIICHVTVETTGTMLMGSEIGAALTALQPLGIDMIGLNCATGPDEMSEHLRYLSKHADIP 260
+I VT+E G ML+GSEIGAALTAL+PLGID+IGLNCATGP EMSEHLRYLS+HA +
Sbjct: 188 VLIAQVTIEQNGAMLLGSEIGAALTALEPLGIDLIGLNCATGPAEMSEHLRYLSRHARVG 247
Query: 261 VSVMPNAGLPVLGKNGAEYPLEAEDLAQALAGFVSEYGLSMVGGCCGTTPEHIRAVRDAV 320
+S MPNAGLP L +GA YPL ++LA A F +YGLS+VGGCCGTTPEH+R V + V
Sbjct: 248 LSCMPNAGLPELTPDGARYPLTPQELADAHDAFTRDYGLSLVGGCCGTTPEHLRLVVERV 307
Query: 321 VGVPEQETSTLTKIPAGPVEQASREVEKEDSVASLYTSVPLSQETGISMIGERTNSNGSK 380
G E A R E +SLY VP Q+T IGERTN+NGSK
Sbjct: 308 RGR----------------ELAPRRPRPEPGASSLYQHVPFKQDTSYLAIGERTNANGSK 351
Query: 381 AFREAMLSGDWEKCVDIAKQQTRDGAHMLDLCVDYVGRDGTADMATLAALLATSSTLPIM 440
AFREAML+ W+ CV IA+ Q RDGAHM+DLCVDYVGRDG ADM LA LAT+STLPIM
Sbjct: 352 AFREAMLAERWDDCVRIARDQARDGAHMIDLCVDYVGRDGVADMKELAFRLATASTLPIM 411
Query: 441 IDSTEPEVIRTGLEHLGGRSIVNSVNFEDGDGPESRYQRIMKLVKQHGAAVVALTIDEEG 500
+DSTEP V+R GLE LGGR++VNSVN+EDG GP SR+ R M V++HGAAVVA+ IDE G
Sbjct: 412 LDSTEPAVLRAGLEMLGGRAVVNSVNYEDGRGPGSRFHRTMTAVREHGAAVVAMCIDEGG 471
Query: 501 QARTAEHKVRIAKRLIDDITGSYGLDIKDIVVDCLTFPISTGQEETRRDGIETIEAIREL 560
QART E KVRIA +I+D+TG++G+ ++DIVVDCLTFPI+TGQEETRRD +ETIEAI EL
Sbjct: 472 QARTREDKVRIACEIIEDLTGNWGMRLEDIVVDCLTFPIATGQEETRRDALETIEAIAEL 531
Query: 561 KKLYPEIHTTLGLSNISFGLNPAARQVLNSVFLNECIEAGLDSAIAHSSKILPMNRIDDR 620
K+ YP++ TTLG+SN+SFGLNPAAR VLNSVFLNEC+ AGLDSAI H+SKILPMNRI D
Sbjct: 532 KRRYPQVQTTLGISNVSFGLNPAARVVLNSVFLNECVNAGLDSAIVHASKILPMNRIPDE 591
Query: 621 QREVALDMVYDRRTEDYDPLQEFMQLFEGVSAADAKDARAEQLAAMPLFERLAQRIIDGD 680
QR+VALDMVYDRR E YDPLQ FM+LFEGVSA + + +RA++LAA+PL+ERL +RIIDG+
Sbjct: 592 QRQVALDMVYDRRREGYDPLQRFMELFEGVSAKELRASRAQELAALPLWERLKRRIIDGE 651
Query: 681 KNGLEDDLEAGMKEKSPIAIINEDLLNGMKTVGELFGSGQMQLPFVLQSAETMKTAVAYL 740
NG+E DL+ ++ + + IIN+ LL+GMKTVG+LFGSGQMQLPFVLQSAE MK AVAYL
Sbjct: 652 ANGMEADLDEALQSRPALEIINDVLLDGMKTVGDLFGSGQMQLPFVLQSAEVMKAAVAYL 711
Query: 741 EPFMEEEAEATGSAQAEGKGKIVVATVKGDVHDIGKNLVDIILSNNGYDVVNLGIKQPLS 800
EP ME+ A+ GKG+IV+ATVKGDVHDIGKNLVDIILSNNGY+V+NLGIKQP+S
Sbjct: 712 EPHMEKSADG-------GKGRIVLATVKGDVHDIGKNLVDIILSNNGYEVINLGIKQPIS 764
Query: 801 AMLEAAEEHKADVIGMSGLLVKSTVVMKENLEEMNNAG-ASNYPVILGGAALTRTYVEND 859
A++EAA+EH+ADVIGMSGLLVKSTVVMKENLEE+N G A +PV+LGGAALTR YVE D
Sbjct: 765 AIVEAAKEHRADVIGMSGLLVKSTVVMKENLEELNARGLARQWPVLLGGAALTRAYVEQD 824
Query: 860 LNEVYTGEVYYARDAFEGLRLMDEVMAEKRGEGLDPNSPEAIEQAKKKAERKARNERSRK 919
L E++ GEV YARDAFEGLRLMD MA KRGE E A+ RK R K
Sbjct: 825 LAELFDGEVRYARDAFEGLRLMDAFMAVKRGE----------EGAQLPPLRKRRVASGAK 874
Query: 920 IAAERKANAAPVIVPERSDVSTDTPTAAPPFWGTRIVKGLPLAEFLGNLDERALFMGQWG 979
+ AP +P RSDV+TD P PPFWG RIVKG+PLA++ LDERA FMGQWG
Sbjct: 875 LKV-----TAPEDMPARSDVATDNPVPEPPFWGDRIVKGIPLADYAAFLDERATFMGQWG 929
Query: 980 LKSTRGNEGPSYEDLVETEGRPRLRYWLDRLKSEGILDHVALVYGYFPAVAEGDDVVILE 1039
LK RG +GPSYE+LVETEGRPRLR WLDR++SEG+++ A+VYGYFPAV+EGDD+VIL
Sbjct: 930 LKPARGGDGPSYEELVETEGRPRLRMWLDRIQSEGLIE-AAVVYGYFPAVSEGDDLVIL- 987
Query: 1040 SPDPHAAERMRFSFPRQQRGRFLCIADFIRPREQAVKDGQVDVMPFQLVTMGNPIADFAN 1099
+ +ER R +FPRQ+R R LC+ADF RPRE G+ DV+ FQLVT+G ++
Sbjct: 988 --NDDGSERERITFPRQRRDRHLCLADFFRPRE----SGETDVVAFQLVTVGAKVSQATA 1041
Query: 1100 ELFAANEYREYLEVHGIGVQLTEALAEYWHSRVRSELKLNDGGSVADFDPEDKTKFFDLD 1159
ELFA N YREYLE+HG+ VQLTEALAEYWH+RVR E+ D DP D FF +D
Sbjct: 1042 ELFAKNSYREYLELHGLSVQLTEALAEYWHARVREEI------GFGDQDPADLDGFFKVD 1095
Query: 1160 YRGARFSFGYGSCPDLEDRAKLVELLEPGRIGVELSEELQLHPEQSTDAFVLYHPEAKYF 1219
YRGAR+SFGY +CPDLE+RA ++ LL P RIGV LSEE QL PEQSTDA + +HPEAKYF
Sbjct: 1096 YRGARYSFGYPACPDLENRAVVMRLLRPERIGVTLSEEFQLVPEQSTDALIAHHPEAKYF 1155
Query: 1220 NV 1221
NV
Sbjct: 1156 NV 1157
Lambda K H
0.316 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 3570
Number of extensions: 182
Number of successful extensions: 11
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 1221
Length of database: 1157
Length adjustment: 47
Effective length of query: 1174
Effective length of database: 1110
Effective search space: 1303140
Effective search space used: 1303140
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Align candidate WP_012852642.1 TCUR_RS11345 (methionine synthase)
to HMM TIGR02082 (metH: methionine synthase (EC 2.1.1.13))
../bin/blast/fastacmd -i /tmp/list.1249.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.1249.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.
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