Align 2-isopropylmalate synthase (EC 2.3.3.13) (characterized)
to candidate WP_012853558.1 TCUR_RS15940 2-isopropylmalate synthase
Query= BRENDA::P9WQB3
(644 letters)
>NCBI__GCF_000024385.1:WP_012853558.1
Length = 569
Score = 704 bits (1816), Expect = 0.0
Identities = 363/610 (59%), Positives = 440/610 (72%), Gaps = 48/610 (7%)
Query: 36 QRASSMPVNRYRPFAEEVEPIRLRNRTWPDRVIDRAPLWCAVDLRDGNQALIDPMSPARK 95
Q+ S MP +RYRPF P+ L +RTWP++ I +AP W + DLRDGNQALIDPM PARK
Sbjct: 5 QQPSGMPFHRYRPFP----PVDLPDRTWPNKTITQAPRWLSTDLRDGNQALIDPMDPARK 60
Query: 96 RRMFDLLVRMGYKEIEVGFPSASQTDFDFVREIIEQGAIPDDVTIQVLTQCRPELIERTF 155
+MF LLVRMGYKEIEVGFP+ASQTDFDFVR +IE+ IPDDV I VLTQ R ELIERT
Sbjct: 61 LKMFQLLVRMGYKEIEVGFPAASQTDFDFVRLLIEEDHIPDDVQISVLTQAREELIERTV 120
Query: 156 QACSGAPRAIVHFYNSTSILQRRVVFRANRAEVQAIATDGARKCVEQAAKYPGT-QWRFE 214
Q+ GAPRA VH YN+T+ L RRVVF R E +A+A +G R ++ A +Y G + +E
Sbjct: 121 QSLVGAPRATVHLYNATAPLFRRVVFGIGRDECKALAVEGTRHVMKFAEQYLGDCDFGYE 180
Query: 215 YSPESYTGTELEYAKQVCDAVGEVIAPTPERPIIFNLPATVEMTTPNVYADSIEWMSRNL 274
YSPE + TEL++A +VC+AV +V P P+R II NLP+T+E +TPNVYAD +EWMSRNL
Sbjct: 181 YSPEIFIDTELDFALEVCEAVMDVWQPGPDREIILNLPSTIERSTPNVYADQVEWMSRNL 240
Query: 275 ANRESVILSLHPHNDRGTAVAAAELGFAAGADRIEGCLFGNGERTGNVCLVTLGLNLFSR 334
+ RE V LS+HPHNDRGTAVA+AEL AGADR+EGCLFGNGERTGNVCLVTLG+NL+S+
Sbjct: 241 SRREHVCLSVHPHNDRGTAVASAELAVMAGADRVEGCLFGNGERTGNVCLVTLGMNLYSQ 300
Query: 335 GVDPQIDFSNIDEIRRTVEYCNQLPVHERHPYGGDLVYTAFSGSHQDAINKGLDAMKLDA 394
G+DPQIDFS+IDEIRRTVEYCNQLPVHERHPY GDLVYT+FSGSHQDAINKG A++ DA
Sbjct: 301 GIDPQIDFSDIDEIRRTVEYCNQLPVHERHPYAGDLVYTSFSGSHQDAINKGFAALERDA 360
Query: 395 DAADCDVDDMLWQVPYLPIDPRDVGRTYEAVIRVNSQSGKGGVAYIMKTDHGLSLPRRLQ 454
A VD WQ+PYLPIDP+DVGRTYEAVIRVNSQSGKGGVAYIMKT+H L LPR+LQ
Sbjct: 361 AEAGVPVDQYRWQMPYLPIDPKDVGRTYEAVIRVNSQSGKGGVAYIMKTEHALDLPRKLQ 420
Query: 455 IEFSQVIQKIAEGTAGEGGEVSPKEMWDAFAEEYLAPVRPLERIRQHVDAADDDGGTTSI 514
IEFS+V+Q + T EGGEV+P++MW F EYL+ + + + D+ +
Sbjct: 421 IEFSRVVQ---QHTDTEGGEVTPEQMWQIFEREYLSSGPRIGLLAHRTSSRVDE--KDHL 475
Query: 515 TATVKINGVETEISGSGNGPLAAFVHALADVGFDVAVLDYYEHAMSAGDDAQAAAYVEAS 574
T V+++G EI G GNGP++AFV AL VG DV VLDY EHA+S+G DA+AAAY+E
Sbjct: 476 TCDVRLDGEIREIEGVGNGPISAFVDALGTVGIDVRVLDYAEHALSSGSDAKAAAYIECE 535
Query: 575 VTIASPAQPGEAGRHASDPVTIASPAQPGEAGRHASDPVTSKTVWGVGIAPSITTASLRA 634
+ + +WGVGI + TASL+
Sbjct: 536 --------------------------------------IGGRVLWGVGIDANTVTASLKG 557
Query: 635 VVSAVNRAAR 644
V+SAVNRAAR
Sbjct: 558 VLSAVNRAAR 567
Lambda K H
0.317 0.133 0.399
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 1009
Number of extensions: 40
Number of successful extensions: 6
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 2
Number of HSP's successfully gapped: 2
Length of query: 644
Length of database: 569
Length adjustment: 37
Effective length of query: 607
Effective length of database: 532
Effective search space: 322924
Effective search space used: 322924
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 53 (25.0 bits)
Align candidate WP_012853558.1 TCUR_RS15940 (2-isopropylmalate synthase)
to HMM TIGR00970 (leuA: 2-isopropylmalate synthase (EC 2.3.3.13))
../bin/blast/fastacmd -i /tmp/list.23881.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.23881.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.
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