Align methionine synthase; EC 2.1.1.13 (characterized)
to candidate WP_018232494.1 THITHI_RS0107645 methionine synthase
Query= CharProtDB::CH_090726
(1227 letters)
>NCBI__GCF_000378965.1:WP_018232494.1
Length = 1250
Score = 1695 bits (4389), Expect = 0.0
Identities = 843/1247 (67%), Positives = 1001/1247 (80%), Gaps = 25/1247 (2%)
Query: 4 KVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFADWPCDLKGNNDLLVLSKPEV 63
++ L ++ + IL+LDG MGTMIQ Y L E D+RGERFADW DLKGNNDLLVL++PE+
Sbjct: 5 RIRLLETRIKDHILILDGAMGTMIQGYELQEQDYRGERFADWNIDLKGNNDLLVLTRPEI 64
Query: 64 IAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAEINFAAAKLARACADEWTARTP 123
IA IH Y EAGADI+ETNTFN+T +AMADY ME + EIN AA++AR AD WTA+ P
Sbjct: 65 IAEIHGQYLEAGADIVETNTFNATRVAMADYAMEDMVPEINREAARIAREAADAWTAKDP 124
Query: 124 EKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDGLVAAYRESTKALVEGGADLILIETV 183
KPR+VAGVLGPTNRTASISPDVNDP FRN+ FD LVA+YRE+ +AL+EGGADL+LIETV
Sbjct: 125 AKPRFVAGVLGPTNRTASISPDVNDPGFRNVDFDTLVASYREAAEALIEGGADLLLIETV 184
Query: 184 FDTLNAKAAVFAVKTEFEALGVELPIMISGTITDASGRTLSGQTTEAFYNSLRHAEALTF 243
FDTLNAKAAVFAV+T F+ G LP+MISGTITDASGRTL+GQ TEAF+NSLRHA +F
Sbjct: 185 FDTLNAKAAVFAVETLFDETGQRLPVMISGTITDASGRTLTGQVTEAFWNSLRHARPFSF 244
Query: 244 GLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAQAGF 303
GLNCALGP ELR YV+ELSR+A+C+V+AHPNAGLPN FGEYDL + MA IREWA++GF
Sbjct: 245 GLNCALGPKELRAYVEELSRLADCHVSAHPNAGLPNEFGEYDLSPEQMAVHIREWAESGF 304
Query: 304 LNIVGGCCGTTPQHIAAMSRAVEGLAPRKLPEIPVACRLSGLEPLNIGEDSLFVNVGERT 363
LNIVGGCCGTTP HI A++ AV + PR +PE ACRLSGLEP NI +SLFVNVGERT
Sbjct: 305 LNIVGGCCGTTPPHIRAIADAVADITPRTVPETVPACRLSGLEPCNIDAESLFVNVGERT 364
Query: 364 NVTGSAKFKRLIKEEKYSEALDVARQQVENGAQIIDINMDEGMLDAEAAMVRFLNLIAGE 423
NVTGSA+FKRLIK+ Y AL+VA QVENGAQIID+NMDEGMLD++AAMVRFLNL+A E
Sbjct: 365 NVTGSARFKRLIKDGDYETALEVAASQVENGAQIIDVNMDEGMLDSKAAMVRFLNLMASE 424
Query: 424 PDIARVPIMIDSSKWDVIEKGLKCIQGKGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVM 483
PDI+RVP+MIDSSKW+VIE GLKCIQGKG+VNSISMKEG + FI HAKL+RRYGAAV+VM
Sbjct: 425 PDISRVPVMIDSSKWEVIEAGLKCIQGKGVVNSISMKEGEETFIEHAKLVRRYGAAVIVM 484
Query: 484 AFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFI 543
AFDEQGQADT+ RK+EIC+RAY+ILTE+VGFP EDIIFDPNIFA+ATGIEEHNNY DFI
Sbjct: 485 AFDEQGQADTKERKVEICQRAYRILTEQVGFPAEDIIFDPNIFAIATGIEEHNNYGVDFI 544
Query: 544 GACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLA 603
A +IK+ LPHAL+SGGVSNVSFSFRGN+ VREAIHAVFLY+AI GMDMGIVNAGQLA
Sbjct: 545 EATREIKKTLPHALVSGGVSNVSFSFRGNERVREAIHAVFLYHAIHAGMDMGIVNAGQLA 604
Query: 604 IYDDLPAELRDAVEDVILNRRDDGTERLLELAEKYRGSKTDDTANAQQAEWRSWEVNKRL 663
+YD++ ELR+ VEDV+LNRR+D TERLLE AE+YRG + A A+ EWRS V KRL
Sbjct: 605 VYDEVDPELRELVEDVVLNRREDATERLLEAAERYRGEGGE--AKAEDLEWRSLPVEKRL 662
Query: 664 EYSLVKGITEFIEQDTEEARQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSAR 723
++LVKGI + +D EEARQQ PI+VIEGPLMDGMNVVGDLFG+G+MFLPQVVKSAR
Sbjct: 663 AHALVKGIDAHVVEDAEEARQQVDHPIKVIEGPLMDGMNVVGDLFGDGRMFLPQVVKSAR 722
Query: 724 VMKQAVAYLEPFIEASKEQG-KTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGV 782
VMK+AVA+L PFIEA K++G + NGK+++ATVKGDVHDIGKNIVGVVLQCNN++++DLGV
Sbjct: 723 VMKKAVAHLIPFIEALKKEGDRPNGKVLMATVKGDVHDIGKNIVGVVLQCNNFQVIDLGV 782
Query: 783 MVPAEKILRTAKEVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHT 842
MVPA+KIL TA E + D+IGLSGLITPSL+EM ++AKEMER +PLLIGGATTS++HT
Sbjct: 783 MVPAQKILDTAVEQDVDVIGLSGLITPSLEEMSHMAKEMERLSMKLPLLIGGATTSRSHT 842
Query: 843 AVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTP 902
AVKIE +YSGPTV+V++ASR VGVV L+S++ RDD+VA R +YE VR+ H ++
Sbjct: 843 AVKIEPHYSGPTVWVKDASRAVGVVQNLISESTRDDYVAGIRADYEEVRVNHAGRQKTQK 902
Query: 903 PVTLEAARDNDFAFDWQAYTPP---------------VAHRLGVQEV-----EASIETLR 942
+TLE AR+N DWQ Y PP V H G V + +E L+
Sbjct: 903 WLTLEQARENRAPIDWQGYEPPRPRVLDSEPAGDGITVLHPYGPDSVVIRFDDYPLEELK 962
Query: 943 NYIDWTPFFMTWSLAGKYPRILEDEVVGVEAQRLFKDANDMLDKLSAEKTLNPRGVVGLF 1002
+YIDWTPFF W L YPRI EDEVVG EA++LFKDA MLD++ E L RGV+G F
Sbjct: 963 DYIDWTPFFHAWELHAAYPRIFEDEVVGEEAKKLFKDATAMLDRIIGEGWLKARGVIGFF 1022
Query: 1003 PANRV-GDDIEIYRDETRTHVINVSHHLRQQTEKTGFA-NYCLADFVAPKLSGKADYIGA 1060
PAN V DDIE+YRDE R + HHLRQQTE+ G N CLADFVAP+ + DY+G
Sbjct: 1023 PANSVETDDIELYRDEDRKQPLMRLHHLRQQTERRGKGPNQCLADFVAPRDTAIPDYLGG 1082
Query: 1061 FAVTGGLEEDALADAFEAQHDDYNKIMVKALADRLAEAFAEYLHERVRKVYWGYAPNENL 1120
FAVT G+ D FE HDDY+ IM+KALADRLAEA AE +HERVR+ +WGYAP+E L
Sbjct: 1083 FAVTAGIGIDEHVKRFEEAHDDYHAIMLKALADRLAEALAERMHERVRREFWGYAPDEAL 1142
Query: 1121 SNEELIRENYQGIRPAPGYPACPEHTEKATIWELLEVEKHTGMKLTESFAMWPGASVSGW 1180
NE LI+E YQGIRPAPGYPACPEHTEK +WELL+ ++ GM++TESFAM P A+VSGW
Sbjct: 1143 DNESLIKEKYQGIRPAPGYPACPEHTEKGLLWELLDPVENAGMRITESFAMLPTAAVSGW 1202
Query: 1181 YFSHPDSKYYAVAQIQRDQVEDYARRKGMSVTEVERWLAPNLGYDAD 1227
YF+HP+++Y+ V ++ RDQV DYARRKGM TE ERWLAPNLGY+ +
Sbjct: 1203 YFAHPEARYFNVGKVNRDQVADYARRKGMKPTEAERWLAPNLGYEPE 1249
Lambda K H
0.318 0.134 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 3961
Number of extensions: 168
Number of successful extensions: 8
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 1227
Length of database: 1250
Length adjustment: 48
Effective length of query: 1179
Effective length of database: 1202
Effective search space: 1417158
Effective search space used: 1417158
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 59 (27.3 bits)
Align candidate WP_018232494.1 THITHI_RS0107645 (methionine synthase)
to HMM TIGR02082 (metH: methionine synthase (EC 2.1.1.13))
../bin/blast/fastacmd -i /tmp/list.11851.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.11851.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.
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