Alignments for a candidate for leuA in Alkalihalobacterium alkalinitrilicum DSM 22532

Align 2-isopropylmalate synthase (EC 2.3.3.13) (characterized)
to candidate WP_078427294.1 BK574_RS02120 2-isopropylmalate synthase

Query= BRENDA::Q9JZG1
         (517 letters)



>NCBI__GCF_002019605.1:WP_078427294.1
          Length = 520

 Score =  451 bits (1160), Expect = e-131
 Identities = 226/501 (45%), Positives = 341/501 (68%), Gaps = 6/501 (1%)

Query: 5   NRVIIFDTTLRDGEQSPGAAMTKEEKIRVARQLEKLGVDIIEAGFAAASPGDFEAVNAIA 64
           ++VI+FDTTLRDGEQ+PG  + + +K+++A +LEKLG+DIIEAGFAAASPGD +AV A+A
Sbjct: 4   DQVILFDTTLRDGEQTPGVNLNENDKVKIALRLEKLGIDIIEAGFAAASPGDAKAVRAVA 63

Query: 65  KTITKSTVCSLSRAIERDIRQAGEAVAPAPKKRIHTFIATSPIHMEYKLKMKPKQVIEAA 124
           + + K  V SL+R  + DI +  +A        IH FIATSPIH E KL M  ++V++ A
Sbjct: 64  EAVHKPLVVSLARTNKNDIDEVVKAFKGITNVGIHIFIATSPIHRERKLGMTKQEVVDKA 123

Query: 125 VKAVKIAREYTDDVEFSCEDALRSEIDFLAEICGAVIEAGATTINIPDTVGYSIPYKTEE 184
           V++V  A ++ D +EFSCED+ R+E++FL EI   VIEAGAT +N PDTVGY+ P +  E
Sbjct: 124 VESVAYASQFFDHIEFSCEDSTRTELEFLREISEKVIEAGATVLNFPDTVGYTTPEEYTE 183

Query: 185 FFRELIAKTPNGGKVVWSAHCHNDLGLAVANSLAALKGGARQVECTVNGLGERAGNASVE 244
            F+ ++  T    KV+ S HCH+DLGLA++NS+AA+K GA Q+E  +NG+GERAGN ++E
Sbjct: 184 LFQYILNHTRGIEKVILSCHCHDDLGLALSNSIAAMKAGALQIEGCINGIGERAGNVALE 243

Query: 245 EIVMALKVRHDLFGLETGIDTTQIVPSSKLVSTITGYPVQPNKAIVGANAFSHESGIHQD 304
           E+   ++ R + +  +TGI+  +I  +S LVS +TG  + PNKA+VG NA++H SGIHQD
Sbjct: 244 EVAALIETRSEHYQRKTGINLKEIAKTSNLVSRLTGISIPPNKAVVGGNAYAHSSGIHQD 303

Query: 305 GVLKHRETYEIMSAESVGWATNRLSLGKLSGRNAFKTKLADLGIELESEEALNAAFARFK 364
           GV+K + TYEI+  ESVG++  +L LGKLSGR+A K +  +LG  ++ ++ L   F ++K
Sbjct: 304 GVIKDKSTYEILKPESVGFSETKLVLGKLSGRHALKKRYEELGYHVDDQQ-LKEIFTKYK 362

Query: 365 ELADKKREIFDEDLHALVSDEMGSMNAESYKFISQKISTETGEEPRADIVFSIKGEEKR- 423
           EL D+K+EIFD D+ AL+  E  +       F    +     ++ RA +  +I G++++ 
Sbjct: 363 ELTDRKKEIFDNDIIALLESEQPNEGTNYLSFQDVSLQVLNNKQYRAFV--NINGKDQQV 420

Query: 424 --ASATGSGPVDAIFKAIESVAQSGAALQIYSVNAVTQGTESQGETSVRLARGNRVVNGQ 481
               A G+GP+DAIF AI+++      L  Y + +V+QG +S GE  V+++ GN +  G+
Sbjct: 421 IEGIAKGNGPIDAIFNAIDTLINLDVELVDYKITSVSQGKDSLGEVFVKVSSGNSIFQGR 480

Query: 482 GADTDVLVATAKAYLSALSKL 502
           G D D++VA+  AY+ A++++
Sbjct: 481 GMDVDIIVASTTAYIDAINRI 501


Lambda     K      H
   0.313    0.129    0.352 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 634
Number of extensions: 27
Number of successful extensions: 3
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 517
Length of database: 520
Length adjustment: 35
Effective length of query: 482
Effective length of database: 485
Effective search space:   233770
Effective search space used:   233770
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 52 (24.6 bits)

Align candidate WP_078427294.1 BK574_RS02120 (2-isopropylmalate synthase)
to HMM TIGR00973 (leuA: 2-isopropylmalate synthase (EC 2.3.3.13))

Software error:

../bin/blast/fastacmd -i /tmp/list.16008.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.16008.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.

For help, please send mail to the webmaster (help@microbesonline.org), giving this error message and the time and date of the error.