Alignments for a candidate for leuA in Alkalihalobacterium alkalinitrilicum DSM 22532

Align 2-isopropylmalate synthase 1; Alpha-IPM synthase 1; Alpha-isopropylmalate synthase 1; EC 2.3.3.13 (characterized)
to candidate WP_078430192.1 BK574_RS22745 2-isopropylmalate synthase

Query= SwissProt::Q8F445
         (501 letters)



>NCBI__GCF_002019605.1:WP_078430192.1
          Length = 511

 Score =  472 bits (1214), Expect = e-137
 Identities = 241/496 (48%), Positives = 342/496 (68%), Gaps = 1/496 (0%)

Query: 7   VRIFDTTLRDGEQCPGAAMTENEKLEIASQLATMKVDIIEAGFPVSSPVQFQAVERIARE 66
           + +FDTTLRDGEQ  G  +   EK+EIA QL  + VD++EAGFP +SP  F +V+ IA  
Sbjct: 4   INVFDTTLRDGEQSAGVNLNFEEKMEIAKQLERLGVDVMEAGFPAASPGDFNSVKAIADT 63

Query: 67  TEGPMIAALARAMKADIEAASKALQPAKKRRIHTFIASSPIHMKYKLGKEPKEVLKMAVE 126
            +G  +  L+R++++DI+AA  AL+   + R+H FIA+SPIHM++KL   P +V++ AV 
Sbjct: 64  IKGCSVIGLSRSVESDIDAAWDALKGGAEPRLHVFIATSPIHMEHKLRLTPDQVVENAVA 123

Query: 127 AVTLCRQFVDDVEFSPEDATRSEPEFLRELCEAVIAAGATTINIPDTVGYTTPAEYGGLF 186
           AV         +++S EDA RS+ +FL  + E VI AGA+ INIPDTVGY TP E   +F
Sbjct: 124 AVKYAATRFPKIQWSAEDACRSDLDFLVRIIEQVIDAGASVINIPDTVGYITPKEITHIF 183

Query: 187 KFLLSNVRGAEKIIFSAHCHNDLGLATANSLAAVQNGARQIECTINGIGERAGNTAMEEV 246
            +L +NVR  +K I S HCH+DLGLATANSLAA++ GA Q+ECTINGIGERAGN ++EE+
Sbjct: 184 SYLKNNVRNMDKAILSTHCHDDLGLATANSLAAIEAGADQVECTINGIGERAGNASLEEI 243

Query: 247 VMAMRTRKDTFGIQTQIKTEEIARASYLVKTITGMLVQPNKAIVGANAFAHESGIHQDGV 306
            +A+  R D +   T I  +EI R S LV  +TGM+V  NKA+VG NAFAHESGIHQDGV
Sbjct: 244 AVALHIRNDFYKANTGITLKEIKRTSSLVSKLTGMIVPNNKAVVGNNAFAHESGIHQDGV 303

Query: 307 IKHRETYEIMKPETVGLSSNRMVLGRHSGRAGFKDRIVKLGFSPQVEELEAAYQRFLEIA 366
           +K + TYEI+ PE VG+SSNRMVLG+HSGR  FKD+I +LG++   E+L   ++ F E+A
Sbjct: 304 LKEKSTYEIITPELVGVSSNRMVLGKHSGRHAFKDKIKELGYTASDEQLNKVFKAFKELA 363

Query: 367 DRKKEIYDEDIRALFSEEARKSTGDRFQLEGFTVSTGTKSTPTAGVRI-LIDGHVREESA 425
           D+KKEI ++DI AL +EE   +    ++++   V+ GT + PTA + + + DG V +E+A
Sbjct: 364 DKKKEITEDDIFALMTEEKIGAAVQYYEVDSLQVNYGTANIPTATITMKMPDGEVVQEAA 423

Query: 426 TGDGPVDAIYKAIQKTTGMDPEVSRLVISPVTEGQDAMAEASVTLEYKGDRVVGKGSSTD 485
           TG G V+AIY  +++      ++    I  +T G+DA+AE  V + + G    G+G++ D
Sbjct: 424 TGSGSVEAIYNTLERIIASPVKLLDYRIQSITGGRDALAEVYVKVRFDGTETSGRGTAHD 483

Query: 486 IIEACSRAYISALNRL 501
           ++EA +RAYI+A+NR+
Sbjct: 484 VLEASARAYINAVNRV 499


Lambda     K      H
   0.316    0.132    0.364 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 626
Number of extensions: 20
Number of successful extensions: 2
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 501
Length of database: 511
Length adjustment: 34
Effective length of query: 467
Effective length of database: 477
Effective search space:   222759
Effective search space used:   222759
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 52 (24.6 bits)

Align candidate WP_078430192.1 BK574_RS22745 (2-isopropylmalate synthase)
to HMM TIGR00973 (leuA: 2-isopropylmalate synthase (EC 2.3.3.13))

Software error:

../bin/blast/fastacmd -i /tmp/list.18813.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.18813.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.

For help, please send mail to the webmaster (help@microbesonline.org), giving this error message and the time and date of the error.