Align malonate-semialdehyde dehydrogenase (EC 1.2.1.15); malonate-semialdehyde dehydrogenase (acetylating) (EC 1.2.1.18); methylmalonate-semialdehyde dehydrogenase (CoA-acylating) (EC 1.2.1.27) (characterized)
to candidate WP_086510928.1 BZY95_RS16190 CoA-acylating methylmalonate-semialdehyde dehydrogenase
Query= BRENDA::A0A081YAY7
(498 letters)
>NCBI__GCF_002151265.1:WP_086510928.1
Length = 503
Score = 606 bits (1562), Expect = e-178
Identities = 302/499 (60%), Positives = 376/499 (75%), Gaps = 7/499 (1%)
Query: 4 IKHLIGGELIA-DTGRTADVFNPSTGEAVRKVPLADRETMQQAIDAAKAAFPAWRNTPPA 62
I H I G++ + ++GR V+NP+TG+ +V LA R + A+ AAKAAFPAW +TPP
Sbjct: 6 IAHYIAGQMTSGESGRHQSVYNPATGQVTGQVALASRADVATAVAAAKAAFPAWADTPPI 65
Query: 63 KRAQVLFRFKQLLEANEERIVKLISEEHGKTIEDAAGELKRGIENVEYATAAPEILKGEY 122
+RA+VLF+F +LL AN++ + + I+ EHGK DA GE+ RGI+ VE+A P++LKG++
Sbjct: 66 RRARVLFKFLELLNANKDELARAITLEHGKVFTDAQGEVARGIDIVEFACGIPQLLKGDF 125
Query: 123 SRNVGPNIDAWSDFQPIGVVAGITPFNFPAMVPLWMYPLAIACGNTFILKPSERDPSSTL 182
+ V ID W+ QP+GVVAGITPFNFPAMVP+WM+P+AIA GNTFILKPS DPS++L
Sbjct: 126 TEQVSNGIDNWTVRQPLGVVAGITPFNFPAMVPMWMFPVAIAAGNTFILKPSPTDPSASL 185
Query: 183 LIAELFHEAGLPKGVLNVVHGDKGAVDALIEAPEVKALSFVGSTPIAEYIYSEGTKRGKR 242
LIAEL +AGLP GV NVV GDK +VDALIE P+V+ALSFVGSTPIA IY G + GKR
Sbjct: 186 LIAELLKQAGLPDGVFNVVQGDKESVDALIEHPDVQALSFVGSTPIANLIYENGARHGKR 245
Query: 243 VQALGGAKNHAVLMPDADLDNAVSALMGAAYGSCGERCMAISVAVCVGDQIADALVQKLV 302
VQALGGAKNH V+MPDADLD AV AL+GAAYGS GERCMAISVAV VGD +AD +V +L
Sbjct: 246 VQALGGAKNHMVVMPDADLDKAVDALIGAAYGSAGERCMAISVAVLVGD-VADKIVPRLA 304
Query: 303 PQIKGLKIGAGTSCGLDMGPLVTGAARDKVTGYIDTGVAQGAELVVDGRGYKVA----GH 358
+ + LK+ G +MGP+VT A ++TGYI+ GVA+GAELVVDGR + A G
Sbjct: 305 ERARALKVKNGLELDAEMGPIVTAQAHQRITGYIEKGVAEGAELVVDGREFDAATTGDGC 364
Query: 359 ENGFFLGGTLFDRVTPEMTIYKEEIFGPVLCIVRVNSLEEAMQLINDHEYGNGTCIFTRD 418
GF++GG+LFD VTPEMTIYKEEIFGPVL VRV + A+QLINDHE+GNG FT
Sbjct: 365 GEGFWMGGSLFDHVTPEMTIYKEEIFGPVLACVRVPDVATAIQLINDHEFGNGVSCFTES 424
Query: 419 GEAARLFCDEIEVGMVGVNVPLPVPVAYHSFGGWKRSLFGDLHAYGPDGVRFYTKRKAIT 478
G AR F I+VGMVG+NVP+PVP+A+H FGGWKRSLFGD HAYG +GVRFYTK+K+I
Sbjct: 425 GSVAREFGRRIQVGMVGINVPIPVPMAWHGFGGWKRSLFGDTHAYGEEGVRFYTKQKSIM 484
Query: 479 QRWPQRKSHEAAQFAFPSN 497
QRW + A+FA P++
Sbjct: 485 QRWSD-SINAGAEFAMPTH 502
Lambda K H
0.319 0.137 0.411
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 767
Number of extensions: 24
Number of successful extensions: 3
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 498
Length of database: 503
Length adjustment: 34
Effective length of query: 464
Effective length of database: 469
Effective search space: 217616
Effective search space used: 217616
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 52 (24.6 bits)
Align candidate WP_086510928.1 BZY95_RS16190 (CoA-acylating methylmalonate-semialdehyde dehydrogenase)
to HMM TIGR01722 (mmsA: methylmalonate-semialdehyde dehydrogenase (acylating) (EC 1.2.1.27))
../bin/blast/fastacmd -i /tmp/list.20487.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.20487.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.
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