GapMind for catabolism of small carbon sources

 

catabolism of small carbon sources in Cereibacter sphaeroides ATCC 17029

Pathways are sorted by name. Sort by completeness instead.

Pathway Steps
acetate actP, acs
D-alanine Pf6N2E2_5402, Pf6N2E2_5403, Pf6N2E2_5404, Pf6N2E2_5405, dadA
alanine snatA
arabinose araE, xacB, xacC, xacD, xacE, xacF
arginine bgtB, artP, rocF, odc, puuA, puuB, puuC, puuD, gabT, gabD
asparagine ans, bztA, bztB, bztC, bztD
aspartate bztA, bztB, bztC, bztD
cellobiose bgl, aglE', aglF', aglG', aglK', glk
citrate tctA, tctB, tctC, acn, icd
citrulline PS417_17590, PS417_17595, PS417_17600, PS417_17605, arcB, arcC, odc, puuA, puuB, puuC, puuD, gabT, gabD
deoxyinosine H281DRAFT_01115, H281DRAFT_01114, H281DRAFT_01113, H281DRAFT_01112, deoD, deoB, deoC, adh, acs
deoxyribonate deoxyribonate-transport, deoxyribonate-dehyd, ketodeoxyribonate-cleavage, garK, atoA, atoD, atoB
deoxyribose deoP, deoK, deoC, adh, acs
ethanol etoh-dh-nad, adh, acs
fructose fruA, fruI, 1pfk, fba, tpi
fucose fucP, fucU, fdh, fuconolactonase, fucD, fucDH, KDF-hydrolase
fumarate dctM, dctP, dctQ
galactose galP, galdh, galactonolactonase, dgoD, dgoK, dgoA
galacturonate exuT, udh, gli, gci, kdgD, dopDH
gluconate gntA, gntB, gntC, gntK, edd, eda
glucose aglE', aglF', aglG', aglK', glk
glucose-6-P uhpT
glucosamine gamP, nagB
glucuronate dctP, dctQ, dctM, uxaC, uxuB, uxuA, kdgK, eda
glutamate bztA, bztB, bztC, gltL, gdhA
glycerol glpS, glpT, glpP, glpQ, glpV, glpK, glpD, tpi
histidine aapJ, aapQ, aapM, aapP, hutH, hutU, hutI, hutF, hutG'
isoleucine livF, livG, livJ, livH, livM, ofo, acdH, ech, ivdG, fadA, pccA, pccB, epi, mcm-large, mcm-small
4-hydroxybenzoate pcaK, pobA, praA, xylF, mhpD, mhpE, adh, acs
D-lactate lctP, glcD, glcE, glcF
L-lactate Shew_2731, Shew_2732, L-LDH
lactose lacP, lacZ, galdh, galactonolactonase, dgoD, dgoK, dgoA, glk
leucine aapJ, aapQ, aapM, aapP, ilvE, ofo, liuA, liuB, liuD, liuC, liuE, atoA, atoD, atoB
lysine bgtB, hisP, davB, davA, davT, davD, gcdG, gcdH, ech, fadB, atoB
L-malate dctM, dctP, dctQ
maltose aglE, aglF, aglG, aglK, susB, glk
mannitol mtlE, mtlF, mtlG, mtlK, mt2d, scrK
mannose frcA, frcB, frcC, man-isomerase, scrK
myoinositol iatP, iatA, ibpA, iolG, iolE, iolD, iolB, iolC, iolJ, mmsA, tpi
NAG nagEcba, nagA, nagB
2-oxoglutarate Psest_0084, Psest_0085
phenylacetate ppa, paaK, paaA, paaB, paaC, paaE, paaG, paaZ1, paaZ2, paaJ1, paaF, paaH, paaJ2
phenylalanine aroP, PAH, PCBD, QDPR, HPD, hmgA, maiA, fahA, atoA, atoD, atoB
proline ectP, put1, putA
propionate mctC, prpE, pccA, pccB, epi, mcm-large, mcm-small
putrescine potA, potB, potC, potD, puuA, puuB, puuC, puuD, gabT, gabD
pyruvate dctM, dctP, dctQ
rhamnose rhaT, LRA1, LRA2, LRA3, LRA5, LRA6
ribose frcA, frcB, frcC, rbsK
D-serine cycA, dsdA
serine snatA, sdaB
sorbitol mtlE, mtlF, mtlG, mtlK, sdh, scrK
succinate dctQ, dctM, dctP
sucrose aglE, aglF, aglG, aglK, ams, scrK, glk
threonine snatA, ltaE, adh, acs, gcvP, gcvT, gcvH, lpd
thymidine nupG, deoA, deoB, deoC, adh, acs
trehalose treF, aglE', aglF', aglG', aglK', glk
tryptophan aroP, tnaA
tyrosine aroP, HPD, hmgA, maiA, fahA, atoA, atoD, atoB
valine natA, natB, natC, natD, natE, ofo, acdH, ech, bch, mmsB, mmsA, pccA, pccB, epi, mcm-large, mcm-small
xylitol PLT5, xdhA, xylB
xylose xylT, xylA, xylB

Confidence: high confidence medium confidence low confidence
transporter – transporters and PTS systems are shaded because predicting their specificity is particularly challenging.

This GapMind analysis is from Apr 09 2024. The underlying query database was built on Sep 17 2021.

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About GapMind

Each pathway is defined by a set of rules based on individual steps or genes. Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam). Ublast hits may be split across two different proteins.

A candidate for a step is "high confidence" if either:

where "other" refers to the best ublast hit to a sequence that is not annotated as performing this step (and is not "ignored").

Otherwise, a candidate is "medium confidence" if either:

Other blast hits with at least 50% coverage are "low confidence."

Steps with no high- or medium-confidence candidates may be considered "gaps." For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. Gaps may be due to:

GapMind relies on the predicted proteins in the genome and does not search the six-frame translation. In most cases, you can search the six-frame translation by clicking on links to Curated BLAST for each step definition (in the per-step page).

For more information, see:

If you notice any errors or omissions in the step descriptions, or any questionable results, please let us know

by Morgan Price, Arkin group, Lawrence Berkeley National Laboratory