Annotation: NCBI__GCF_001484605.1:WP_240484271.1
Length: 268 amino acids
Source: GCF_001484605.1 in NCBI
| Pathway | Step | Score | Similar to | Id. | Cov. | Bits | Other hit | Other id. | Other bits |
|---|---|---|---|---|---|---|---|---|---|
| 4-hydroxybenzoate catabolism | paaF | med | 2,3-dehydroadipyl-CoA hydratase (EC 4.2.1.17) (characterized) | 38% | 93% | 136.7 | Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 | 33% | 108.6 |
| L-isoleucine catabolism | ech | med | 2,3-dehydroadipyl-CoA hydratase (EC 4.2.1.17) (characterized) | 38% | 93% | 136.7 | 2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase (EC 5.3.3.18) | 30% | 84.3 |
| phenylacetate catabolism | paaF | med | 2,3-dehydroadipyl-CoA hydratase (EC 4.2.1.17) (characterized) | 38% | 93% | 136.7 | Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 | 33% | 108.6 |
| L-phenylalanine catabolism | paaF | med | 2,3-dehydroadipyl-CoA hydratase (EC 4.2.1.17) (characterized) | 38% | 93% | 136.7 | Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 | 33% | 108.6 |
View WP_240484271.1 at NCBI
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Find functional residues: SitesBLAST
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Predict transmenbrane helices: Phobius
Predict protein localization: PSORTb
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MTEVMNDAGTRLDTSGFVTLLVEEREDRLAVRLHRPAVKNAIDQAMVDELHAVCAHLERT PKILILSGTPANPETGAKAVFASGADIAQLRERRRADALAGINSGIFDRIAKLPMPVIAA LDGFALGGGAELAYAADFRIGTPALRMGNPETNLGILAAAGATWRLKELVGEPMAKQILL AGKVLTGEDCLTIGLISELVDPETLLDAAHALADAIAAQDPLAVRITKAVFHAPREAHPV IDTLAQGMLFESQAKFDRMQAFLDRKKK
This GapMind analysis is from Apr 09 2024. The underlying query database was built on Sep 17 2021.
Each pathway is defined by a set of rules based on individual steps or genes. Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam). Ublast hits may be split across two different proteins.
A candidate for a step is "high confidence" if either:
Otherwise, a candidate is "medium confidence" if either:
Other blast hits with at least 50% coverage are "low confidence."
Steps with no high- or medium-confidence candidates may be considered "gaps." For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. Gaps may be due to:
GapMind relies on the predicted proteins in the genome and does not search the six-frame translation. In most cases, you can search the six-frame translation by clicking on links to Curated BLAST for each step definition (in the per-step page).
For more information, see:
If you notice any errors or omissions in the step descriptions, or any questionable results, please let us know
by Morgan Price, Arkin group, Lawrence Berkeley National Laboratory