GapMind for catabolism of small carbon sources

 

D-serine catabolism

Analysis of pathway D-serine in 276 genomes

Genome Best path
Acidovorax caeni R-24608 cycA, dsdA
Actinokineospora bangkokensis 44EHW cycA, dsdA
Actinomyces timonensis 7400942 cycA, dsdA
Algiphilus aromaticivorans DG1253 cycA, dsdA
Algoriphagus aquaeductus T4 dsdX, dsdA
Algoriphagus machipongonensis PR1 cycA, dsdA
Alicyclobacillus ferrooxydans TC-34 cycA, dsdA
Alishewanella agri BL06 cycA, dsdA
Alistipes indistinctus YIT 12060 cycA, dsdA
Alistipes shahii WAL 8301 cycA, dsdA
Alkalitalea saponilacus SC/BZ-SP2 cycA, dsdA
Amantichitinum ursilacus IGB-41 cycA, dsdA
Amphibacillus jilinensis Y1 cycA, dsdA
Amphritea japonica JAMM 1866 cycA, dsdA
Amycolatopsis halophila YIM 93223 cycA, dsdA
Amycolatopsis xylanica CPCC 202699 cycA, dsdA
Aquimarina agarilytica ZC1 cycA, dsdA
Aquimarina longa SW024 cycA, dsdA
Aquimarina macrocephali JAMB N27 cycA, dsdA
Archaeoglobus sulfaticallidus PM70-1 cycA, dsdA
Arcticibacter svalbardensis MN12-7 cycA, dsdA
Ardenticatena maritima 110S cycA, dsdA
Arenimonas metalli CF5-1 cycA, dsdA
Arenitalea lutea P7-3-5 cycA, dsdA
Azospirillum humicireducens SgZ-5 cycA, dsdA
Azospirillum thiophilum BV-S cycA, dsdA
Bacillus altitudinis 41KF2b cycA, dsdA
Bacillus coahuilensis m4-4 cycA, dsdA
Bacillus cytotoxicus NVH 391-98 cycA, dsdA
Bacillus horneckiae 1P01SC cycA, dsdA
Bacillus okhensis Kh10-101 cycA, dsdA
Bacillus safensis FO-36b cycA, dsdA
Bacillus velezensis CBMB205 cycA, dsdA
Bacteroides clarus YIT 12056 cycA, dsdA
Bacteroides faecis MAJ27 cycA, dsdA
Bacteroides fluxus YIT 12057 cycA, dsdA
Bacteroides oleiciplenus YIT 12058 cycA, dsdA
Barnesiella intestinihominis YIT 11860 cycA, dsdA
Belnapia rosea CPCC 100156 cycA, dsdA
Bizionia argentinensis JUB59 cycA, dsdA
Bradyrhizobium diazoefficiens USDA110 cycA, dsdA
Brevibacterium jeotgali SJ5-8 cycA, dsdA
Brucella inopinata BO1 cycA, dsdA
Brucella microti CCM 4915 cycA, dsdA
Bryobacter aggregatus MPL3 cycA, dsdA
Caldicellulosiruptor hydrothermalis 108 cycA, dsdA
Caldicellulosiruptor kronotskyensis 2002 cycA, dsdA
Carboxydothermus pertinax Ug1 cycA, dsdA
Catellicoccus marimammalium M35/04/3 cycA, dsdA
Chromobacterium vaccinii MWU205 cycA, dsdA
Chryseobacterium angstadtii KM cycA, dsdA
Chryseobacterium arthrosphaerae CC-VM-7 cycA, dsdA
Chryseobacterium viscerum 687B-08 cycA, dsdA
Cloacibacillus porcorum CL-84 cycA, dsdA
Cobetia crustatorum JO1 cycA, dsdA
Collimonas arenae Ter10 dsdX, dsdA
Collimonas pratensis Ter91 cycA, dsdA
Collinsella tanakaei YIT 12063 cycA, dsdA
Coprobacter fastidiosus NSB1 cycA, dsdA
Corynebacterium deserti GIMN1.010 cycA, dsdA
Corynebacterium frankenforstense ST18 cycA, dsdA
Corynebacterium lactis RW2-5 cycA, dsdA
Croceitalea dokdonensis DOKDO 023 cycA, dsdA
Cronobacter condimenti 1330 cycA, dsdA
Cronobacter muytjensii ATCC 51329 cycA, dsdA
Cronobacter universalis NCTC 9529 cycA, dsdA
Desulfatitalea tepidiphila S28bF cycA, dsdA
Desulfotomaculum hydrothermale Lam5 cycA, dsdA
Dethiosulfovibrio salsuginis USBA 82 cycA, dsdA
Devosia chinhatensis IPL18 cycA, dsdA
Devriesea agamarum IMP2 cycA, dsdA
Dialister succinatiphilus YIT 11850 cycA, dsdA
Dietzia timorensis ID05-A0528 cycA, dsdA
Dokdonella koreensis DS-123 cycA, dsdA
Domibacillus robiginosus WS 4628 cycA, dsdA
Duganella sacchari Sac-22 cycA, dsdA
Dyadobacter tibetensis Y620-1 cycA, dsdA
Dyella jiangningensis SBZ3-12 cycA, dsdA
Endozoicomonas montiporae CL-33 cycA, dsdA
Enterococcus termitis LMG 8895 cycA, dsdA
Enterorhabdus caecimuris B7 cycA, dsdA
Epibacterium ulvae U95 cycA, dsdA
Erythrobacter gangjinensis K7-2 dsdX, dsdA
Erythrobacter marinus HWDM-33 cycA, dsdA
Ethanoligenens harbinense YUAN-3 cycA, dsdA
Fervidicella metallireducens AeB cycA, dsdA
Fibrella aestuarina BUZ 2 cycA, dsdA
Flammeovirga pacifica WPAGA1 cycA, dsdA
Flaviramulus ichthyoenteri Th78 cycA, dsdA
Flavobacterium beibuense F44-8 cycA, dsdA
Flavobacterium glycines Gm-149 cycA, dsdA
Flavobacterium sp. LM5 cycA, dsdA
Flavobacterium ummariense DS-12 cycA, dsdA
Frischella perrara PEB0191 cycA, dsdA
Galbibacter marinus ck-I2-15 cycA, dsdA
Gallaecimonas xiamenensis 3-C-1 cycA, dsdA
Geobacter daltonii FRC-32 cycA, dsdA
Gillisia marina CBA3202 cycA, dsdA
Gracilibacillus halophilus YIM-C55.5 cycA, dsdA
Granulicella mallensis MP5ACTX8 cycA, dsdA
Granulicella tundricola MP5ACTX9 cycA, dsdA
Hafnia paralvei ATCC 29927 cycA, dsdA
Haladaptatus cibarius D43 cycA, dsdA
Halioglobus japonicus S1-36 cycA, dsdA
Halobacillus alkaliphilus FP5 cycA, dsdA
Halococcus hamelinensis 100A6 cycA, dsdA
Halomonas salina B6 cycA, dsdA
Halomonas smyrnensis AAD6 cycA, dsdA
Halomonas stevensii S18214 cycA, dsdA
Halomonas titanicae BH1 cycA, dsdA
Halomonas xinjiangensis TRM 0175 cycA, dsdA
Halopiger salifodinae KCY07-B2 cycA, dsdA
Halostagnicola larsenii XH-48 cycA, dsdA
Haloterrigena daqingensis JX313 cycA, dsdA
Herbaspirillum aquaticum IEH 4430 cycA, dsdA
Hippea alviniae EP5-r cycA, dsdA
Hippea jasoniae Mar08-272r cycA, dsdA
Hoeflea phototrophica DFL-43 cycA, dsdA
Hyphomicrobium nitrativorans NL23 cycA, dsdA
Imtechella halotolerans K1 cycA, dsdA
Indibacter alkaliphilus LW1 cycA, dsdA
Jannaschia aquimarina GSW-M26 cycA, dsdA
Jeotgalibacillus soli P9 cycA, dsdA
Kangiella geojedonensis YCS-5 cycA, dsdA
Knoellia flava TL1 cycA, dsdA
Kocuria flava HO-9041 cycA, dsdA
Kocuria turfanensis HO-9042 cycA, dsdA
Laceyella sediminis RHA1 cycA, dsdA
Lacinutrix algicola AKS293 cycA, dsdA
Lacinutrix himadriensis E4-9a cycA, dsdA
Lacinutrix mariniflava AKS432 cycA, dsdA
Lactobacillus curieae CCTCC M 2011381 cycA, dsdA
Lactobacillus delbrueckii ZN7a-9 cycA, dsdA
Lactobacillus hokkaidonensis LOOC260 cycA, dsdA
Lactobacillus oryzae SG293 cycA, dsdA
Lactobacillus pobuzihii E100301 cycA, dsdA
Lactobacillus shenzhenensis LY-73 cycA, dsdA
Lactobacillus silagei IWT126 cycA, dsdA
Leeuwenhoekiella blandensis MED217 cycA, dsdA
Lentibacillus jeotgali Grbi cycA, dsdA
Limnohabitans curvus MWH-C5 cycA, dsdA
Limnohabitans parvus II-B4 cycA, dsdA
Listeria fleischmannii LU2006-1 cycA, dsdA
Luteimonas huabeiensis HB2 cycA, dsdA
Luteipulveratus mongoliensis MN07-A0370 cycA, dsdA
Lutibaculum baratangense AMV1 cycA, dsdA
Lysobacter daejeonensis GH1-9 cycA, dsdA
Magnetovibrio blakemorei MV-1 cycA, dsdA
Marinicella litoralis KMM 3900 cycA, dsdA
Mariniradius saccharolyticus AK6 cycA, dsdA
Marinobacter algicola DG893 cycA, dsdA
Marinobacter guineae M3B cycA, dsdA
Marinobacter psychrophilus 20041 cycA, dsdA
Marinomonas arctica 328 cycA, dsdA
Marivita geojedonensis DPG-138 cycA, dsdA
Martelella endophytica YC6887 cycA, dsdA
Megamonas funiformis YIT 11815 cycA, dsdA
Mesorhizobium ciceri WSM1271 cycA, dsdA
Methanobacterium arcticum M2 cycA, dsdA
Methanobacterium veterum MK4 cycA, dsdA
Methanocella arvoryzae MRE50 cycA, dsdA
Methanococcus aeolicus Nankai-3 cycA, dsdA
Methanoculleus horonobensis T10 cycA, dsdA
Methanolinea tarda NOBI-1 cycA, dsdA
Methanosarcina soligelidi SMA-21 cycA, dsdA
Methanospirillum lacunae Ki8-1 cycA, dsdA
Methanospirillum stamsii Pt1 cycA, dsdA
Methylibium petroleiphilum PM1 cycA, dsdA
Methylobacterium gossipiicola Gh-105 cycA, dsdA
Methylocapsa aurea KYG cycA, dsdA
Methylotenera versatilis 301 cycA, dsdA
Microbacterium profundi Shh49 cycA, dsdA
Microvirga lotononidis WSM3557 cycA, dsdA
Moritella dasanensis ArB 0140 cycA, dsdA
Mucilaginibacter gossypii Gh-67 cycA, dsdA
Mucilaginibacter gossypiicola Gh-48 cycA, dsdA
Mucilaginibacter mallensis MP1X4 cycA, dsdA
Nafulsella turpanensis ZLM-10 cycA, dsdA
Natronomonas moolapensis 8.8.11 cycA, dsdA
Nautilia profundicola AmH cycA, dsdA
Neiella marina J221 cycA, dsdA
Neptunomonas antarctica S3-22 cycA, dsdA
Nocardioides daejeonensis MJ31 cycA, dsdA
Nocardioides dokdonensis FR1436 cycA, dsdA
Nocardiopsis baichengensis YIM 90130 cycA, dsdA
Nocardiopsis gilva YIM 90087 cycA, dsdA
Novosphingobium barchaimii LL02 cycA, dsdA
Novosphingobium fuchskuhlense FNE08-7 cycA, dsdA
Novosphingobium lindaniclasticum LE124 cycA, dsdA
Oceanisphaera arctica V1-41 cycA, dsdA
Ochrobactrum rhizosphaerae PR17 cycA, dsdA
Ochrobactrum thiophenivorans DSM 7216 cycA, dsdA
Oscillibacter ruminantium GH1 cycA, dsdA
Paenisporosarcina indica PN2 cycA, dsdA
Palaeococcus pacificus DY20341 cycA, dsdA
Paludibacter propionicigenes WB4 cycA, dsdA
Pandoraea thiooxydans ATSB16 cycA, dsdA
Pantoea rwandensis LMG 26275 cycA, dsdA
Pedobacter arcticus A12 cycA, dsdA
Photobacterium gaetbulicola Gung47 cycA, dsdA
Photobacterium jeanii R-40508 cycA, dsdA
Phyllobacterium brassicacearum STM 196 cycA, dsdA
Phyllobacterium endophyticum PEPV15 cycA, dsdA
Phyllobacterium leguminum ORS 1419 cycA, dsdA
Planktomarina temperata RCA23 cycA, dsdA
Planococcus halocryophilus Or1 cycA, dsdA
Pleomorphomonas diazotrophica R5-392 cycA, dsdA
Polaribacter dokdonensis DSW-5 cycA, dsdA
Pontibacillus litoralis JSM 072002 cycA, dsdA
Pontibacter lucknowensis DM9 cycA, dsdA
Pontibacter ramchanderi LP43 cycA, dsdA
Pontimonas salivibrio CL-TW6 cycA, dsdA
Porphyrobacter dokdonensis DSW-74 cycA, dsdA
Pseudoalteromonas arctica A 37-1-2 cycA, dsdA
Pseudomonas baetica a390 cycA, dsdA
Pseudomonas litoralis 2SM5 dsdX, dsdA
Pseudomonas taeanensis MS-3 cycA, dsdA
Pseudovibrio axinellae Ad2 cycA, dsdA
Psychrobacter arcticus 273-4 cycA, dsdA
Psychrobacter cryohalolentis K5 dsdX, dsdA
Psychromonas ingrahamii 37 cycA, dsdA
Psychromonas ossibalaenae JAMM 0738 cycA, dsdA
Rhizobium freirei PRF 81 cycA, dsdA
Rhizobium grahamii CCGE 502 cycA, dsdA
Rhizobium subbaraonis JC85 cycA, dsdA
Rhodanobacter denitrificans 2APBS1 cycA, dsdA
Rhodobacter johrii JA192 cycA, dsdA
Rhodobacter maris JA276 cycA, dsdA
Rhodobacter ovatus JA234 cycA, dsdA
Rhodobacter viridis JA737 cycA, dsdA
Rhodococcus qingshengii djl-6-2 cycA, dsdA
Rhodopseudomonas pseudopalustris DSM 123 cycA, dsdA
Roseateles aquatilis CCUG 48205 cycA, dsdA
Roseivirga spongicola UST030701-084 cycA, dsdA
Rubrivirga marina SAORIC-28 cycA, dsdA
Ruegeria conchae TW15 cycA, dsdA
Saccharomonospora marina XMU15 cycA, dsdA
Salinicoccus carnicancri Crm cycA, dsdA
Serinicoccus profundi MCCC 1A05965 cycA, dsdA
Shewanella halifaxensis HAW-EB4 dsdX, dsdA
Skermanella stibiiresistens SB22 cycA, dsdA
Snodgrassella alvi wkB2 cycA, dsdA
Sphaerochaeta globosa Buddy cycA, dsdA
Sphaerochaeta pleomorpha Grapes dsdX, dsdA
Sphingobium baderi LL03 cycA, dsdA
Sphingobium czechense LL01 cycA, dsdA
Sphingobium quisquiliarum P25 cycA, dsdA
Sphingomonas histidinilytica UM2 cycA, dsdA
Sphingomonas indica Dd16 cycA, dsdA
Sphingomonas laterariae LNB2 cycA, dsdA
Sphingopyxis indica DS15 cycA, dsdA
Sphingopyxis terrae UI2 cycA, dsdA
Sporolactobacillus vineae SL153 cycA, dsdA
Streptacidiphilus oryzae TH49 cycA, dsdA
Streptococcus anginosus CCUG 39159 cycA, dsdA
Streptococcus massiliensis 4401825 cycA, dsdA
Streptococcus oralis 7747 cycA, dsdA
Streptococcus oralis AZ_3a cycA, dsdA
Streptomyces kebangsaanensis SUK12 cycA, dsdA
Succinatimonas hippei YIT 12066 cycA, dsdA
Sulfurimonas gotlandica GD1 cycA, dsdA
Tatumella morbirosei LMG 23360 cycA, dsdA
Thauera humireducens SgZ-1 cycA, dsdA
Thermoactinomyces daqus H-18 dsdX, dsdA
Thermobifida halotolerans YIM 90462 cycA, dsdA
Thermodesulfovibrio aggregans TGE-P1 cycA, dsdA
Thermophagus xiamenensis HS1 cycA, dsdA
Thermovenabulum gondwanense R270 cycA, dsdA
Thioclava dalianensis DLFJ1-1 cycA, dsdA
Thiohalospira halophila HL 3 cycA, dsdA
Tistlia consotensis USBA 355 cycA, dsdA
Vagococcus penaei CD276 cycA, dsdA
Verminephrobacter eiseniae EF01-2 cycA, dsdA
Weissella oryzae SG25 cycA, dsdA
Williamsia sterculiae CPCC 203464 cycA, dsdA
Yersinia intermedia Y228 cycA, dsdA

Confidence: high confidence medium confidence low confidence
transporter – transporters and PTS systems are shaded because predicting their specificity is particularly challenging.

This GapMind analysis is from Sep 24 2021. The underlying query database was built on Sep 17 2021.

Links

Downloads

Related tools

About GapMind

Each pathway is defined by a set of rules based on individual steps or genes. Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam). Ublast hits may be split across two different proteins.

A candidate for a step is "high confidence" if either:

where "other" refers to the best ublast hit to a sequence that is not annotated as performing this step (and is not "ignored").

Otherwise, a candidate is "medium confidence" if either:

Other blast hits with at least 50% coverage are "low confidence."

Steps with no high- or medium-confidence candidates may be considered "gaps." For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. Gaps may be due to:

GapMind relies on the predicted proteins in the genome and does not search the six-frame translation. In most cases, you can search the six-frame translation by clicking on links to Curated BLAST for each step definition (in the per-step page).

For more information, see:

If you notice any errors or omissions in the step descriptions, or any questionable results, please let us know

by Morgan Price, Arkin group, Lawrence Berkeley National Laboratory