GapMind for catabolism of small carbon sources

 

D-mannose catabolism

Analysis of pathway mannose in 276 genomes

Genome Best path
Acidovorax caeni R-24608 manP, manA
Actinokineospora bangkokensis 44EHW manP, manA
Actinomyces timonensis 7400942 manX, manY, manZ, manA
Algiphilus aromaticivorans DG1253 manP, manA
Algoriphagus aquaeductus T4 STP6, man-isomerase, scrK
Algoriphagus machipongonensis PR1 STP6, man-isomerase, scrK
Alicyclobacillus ferrooxydans TC-34 manP, manA
Alishewanella agri BL06 gluP, man-isomerase, scrK
Alistipes indistinctus YIT 12060 STP6, mannokinase, manA
Alistipes shahii WAL 8301 STP6, mannokinase, manA
Alkalitalea saponilacus SC/BZ-SP2 STP6, mannokinase, manA
Amantichitinum ursilacus IGB-41 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, man-isomerase, scrK
Amphibacillus jilinensis Y1 manX, manY, manZ, manA
Amphritea japonica JAMM 1866 manP, manA
Amycolatopsis halophila YIM 93223 manP, manA
Amycolatopsis xylanica CPCC 202699 frcA, frcB, frcC, mannokinase, manA
Aquimarina agarilytica ZC1 STP6, mannokinase, manA
Aquimarina longa SW024 manP, manA
Aquimarina macrocephali JAMB N27 manP, manA
Archaeoglobus sulfaticallidus PM70-1 manP, manA
Arcticibacter svalbardensis MN12-7 manP, manA
Ardenticatena maritima 110S manP, manA
Arenimonas metalli CF5-1 manP, manA
Arenitalea lutea P7-3-5 manP, manA
Azospirillum humicireducens SgZ-5 manP, manA
Azospirillum thiophilum BV-S manP, manA
Bacillus altitudinis 41KF2b manP, manA
Bacillus coahuilensis m4-4 STP6, man-isomerase, scrK
Bacillus cytotoxicus NVH 391-98 manP, manA
Bacillus horneckiae 1P01SC manP, manA
Bacillus okhensis Kh10-101 manP, manA
Bacillus safensis FO-36b manP, manA
Bacillus velezensis CBMB205 manP, manA
Bacteroides clarus YIT 12056 gluP, mannokinase, manA
Bacteroides faecis MAJ27 STP6, mannokinase, manA
Bacteroides fluxus YIT 12057 STP6, mannokinase, manA
Bacteroides oleiciplenus YIT 12058 STP6, mannokinase, manA
Barnesiella intestinihominis YIT 11860 STP6, mannokinase, manA
Belnapia rosea CPCC 100156 manP, manA
Bizionia argentinensis JUB59 manP, manA
Bradyrhizobium diazoefficiens USDA110 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, man-isomerase, scrK
Brevibacterium jeotgali SJ5-8 manP, manA
Brucella inopinata BO1 manP, manA
Brucella microti CCM 4915 manP, manA
Bryobacter aggregatus MPL3 manMFS, man-isomerase, scrK
Caldicellulosiruptor hydrothermalis 108 manP, manA
Caldicellulosiruptor kronotskyensis 2002 manP, manA
Carboxydothermus pertinax Ug1 manP, manA
Catellicoccus marimammalium M35/04/3 manX, manY, manZ, manA
Chromobacterium vaccinii MWU205 manP, manA
Chryseobacterium angstadtii KM gluP, mannokinase, manA
Chryseobacterium arthrosphaerae CC-VM-7 STP6, mannokinase, manA
Chryseobacterium viscerum 687B-08 gluP, mannokinase, manA
Cloacibacillus porcorum CL-84 manP, manA
Cobetia crustatorum JO1 STP6, man-isomerase, scrK
Collimonas arenae Ter10 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, man-isomerase, scrK
Collimonas pratensis Ter91 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, man-isomerase, scrK
Collinsella tanakaei YIT 12063 manX, manY, manZ, manA
Coprobacter fastidiosus NSB1 STP6, mannokinase, manA
Corynebacterium deserti GIMN1.010 manP, manA
Corynebacterium frankenforstense ST18 manP, manA
Corynebacterium lactis RW2-5 manP, manA
Croceitalea dokdonensis DOKDO 023 STP6, mannokinase, manA
Cronobacter condimenti 1330 manX, manY, manZ, manA
Cronobacter muytjensii ATCC 51329 manX, manY, manZ, manA
Cronobacter universalis NCTC 9529 manX, manY, manZ, manA
Desulfatitalea tepidiphila S28bF manP, manA
Desulfotomaculum hydrothermale Lam5 manP, manA
Dethiosulfovibrio salsuginis USBA 82 manP, manA
Devosia chinhatensis IPL18 frcA, frcB, frcC, man-isomerase, scrK
Devriesea agamarum IMP2 manP, manA
Dialister succinatiphilus YIT 11850 STP6, man-isomerase, scrK
Dietzia timorensis ID05-A0528 manP, manA
Dokdonella koreensis DS-123 manP, manA
Domibacillus robiginosus WS 4628 STP6, man-isomerase, scrK
Duganella sacchari Sac-22 gluP, man-isomerase, scrK
Dyadobacter tibetensis Y620-1 manP, manA
Dyella jiangningensis SBZ3-12 STP6, man-isomerase, scrK
Endozoicomonas montiporae CL-33 manP, manA
Enterococcus termitis LMG 8895 manX, manY, manZ, manA
Enterorhabdus caecimuris B7 manP, manA
Epibacterium ulvae U95 manP, manA
Erythrobacter gangjinensis K7-2 manP, manA
Erythrobacter marinus HWDM-33 manP, manA
Ethanoligenens harbinense YUAN-3 manP, manA
Fervidicella metallireducens AeB manP, manA
Fibrella aestuarina BUZ 2 gluP, mannokinase, manA
Flammeovirga pacifica WPAGA1 STP6, mannokinase, manA
Flaviramulus ichthyoenteri Th78 manP, manA
Flavobacterium beibuense F44-8 manP, manA
Flavobacterium glycines Gm-149 manP, manA
Flavobacterium sp. LM5 manP, manA
Flavobacterium ummariense DS-12 manP, manA
Frischella perrara PEB0191 manX, manY, manZ, manA
Galbibacter marinus ck-I2-15 manP, manA
Gallaecimonas xiamenensis 3-C-1 gluP, mannokinase, manA
Geobacter daltonii FRC-32 manP, manA
Gillisia marina CBA3202 manP, manA
Gracilibacillus halophilus YIM-C55.5 manP, manA
Granulicella mallensis MP5ACTX8 gluP, mannokinase, manA
Granulicella tundricola MP5ACTX9 gluP, mannokinase, manA
Hafnia paralvei ATCC 29927 manX, manY, manZ, manA
Haladaptatus cibarius D43 manP, manA
Halioglobus japonicus S1-36 manP, manA
Halobacillus alkaliphilus FP5 manP, manA
Halococcus hamelinensis 100A6 manP, manA
Halomonas salina B6 manP, manA
Halomonas smyrnensis AAD6 STP6, man-isomerase, scrK
Halomonas stevensii S18214 manP, manA
Halomonas titanicae BH1 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, man-isomerase, scrK
Halomonas xinjiangensis TRM 0175 manP, manA
Halopiger salifodinae KCY07-B2 TT_C0211, TT_C0327, TT_C0326, TT_C0328, man-isomerase, scrK
Halostagnicola larsenii XH-48 manP, manA
Haloterrigena daqingensis JX313 manP, manA
Herbaspirillum aquaticum IEH 4430 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, man-isomerase, scrK
Hippea alviniae EP5-r manP, manA
Hippea jasoniae Mar08-272r manP, manA
Hoeflea phototrophica DFL-43 frcA, frcB, frcC, man-isomerase, scrK
Hyphomicrobium nitrativorans NL23 manP, manA
Imtechella halotolerans K1 manP, manA
Indibacter alkaliphilus LW1 STP6, man-isomerase, scrK
Jannaschia aquimarina GSW-M26 frcA, frcB, frcC, mannokinase, manA
Jeotgalibacillus soli P9 manP, manA
Kangiella geojedonensis YCS-5 manP, manA
Knoellia flava TL1 frcA, frcB, frcC, mannokinase, manA
Kocuria flava HO-9041 manP, manA
Kocuria turfanensis HO-9042 manP, manA
Laceyella sediminis RHA1 manP, manA
Lacinutrix algicola AKS293 manP, manA
Lacinutrix himadriensis E4-9a manP, manA
Lacinutrix mariniflava AKS432 manP, manA
Lactobacillus curieae CCTCC M 2011381 manP, manA
Lactobacillus delbrueckii ZN7a-9 manX, manY, manZ, manA
Lactobacillus hokkaidonensis LOOC260 manP, manA
Lactobacillus oryzae SG293 STP6, man-isomerase, scrK
Lactobacillus pobuzihii E100301 manX, manY, manZ, manA
Lactobacillus shenzhenensis LY-73 manP, manA
Lactobacillus silagei IWT126 STP6, man-isomerase, scrK
Leeuwenhoekiella blandensis MED217 manP, manA
Lentibacillus jeotgali Grbi manP, manA
Limnohabitans curvus MWH-C5 frcA, frcB, frcC, man-isomerase, scrK
Limnohabitans parvus II-B4 manP, manA
Listeria fleischmannii LU2006-1 manX, manY, manZ, manA
Luteimonas huabeiensis HB2 gluP, man-isomerase, scrK
Luteipulveratus mongoliensis MN07-A0370 manP, manA
Lutibaculum baratangense AMV1 STP6, mannokinase, manA
Lysobacter daejeonensis GH1-9 manP, manA
Magnetovibrio blakemorei MV-1 STP6, mannokinase, manA
Marinicella litoralis KMM 3900 manP, manA
Mariniradius saccharolyticus AK6 STP6, man-isomerase, scrK
Marinobacter algicola DG893 manP, manA
Marinobacter guineae M3B manP, manA
Marinobacter psychrophilus 20041 STP6, mannokinase, manA
Marinomonas arctica 328 frcA, frcB, frcC, man-isomerase, scrK
Marivita geojedonensis DPG-138 frcA, frcB, frcC, man-isomerase, scrK
Martelella endophytica YC6887 STP6, man-isomerase, scrK
Megamonas funiformis YIT 11815 manMFS, mannokinase, manA
Mesorhizobium ciceri WSM1271 frcA, frcB, frcC, man-isomerase, scrK
Methanobacterium arcticum M2 manP, manA
Methanobacterium veterum MK4 manP, manA
Methanocella arvoryzae MRE50 manP, manA
Methanococcus aeolicus Nankai-3 manP, manA
Methanoculleus horonobensis T10 manP, manA
Methanolinea tarda NOBI-1 manP, manA
Methanosarcina soligelidi SMA-21 manP, manA
Methanospirillum lacunae Ki8-1 manP, manA
Methanospirillum stamsii Pt1 manP, manA
Methylibium petroleiphilum PM1 manP, manA
Methylobacterium gossipiicola Gh-105 manP, manA
Methylocapsa aurea KYG manP, manA
Methylotenera versatilis 301 manP, manA
Microbacterium profundi Shh49 manP, manA
Microvirga lotononidis WSM3557 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, man-isomerase, scrK
Moritella dasanensis ArB 0140 manP, manA
Mucilaginibacter gossypii Gh-67 manP, manA
Mucilaginibacter gossypiicola Gh-48 manP, manA
Mucilaginibacter mallensis MP1X4 manP, manA
Nafulsella turpanensis ZLM-10 manP, manA
Natronomonas moolapensis 8.8.11 manP, manA
Nautilia profundicola AmH manP, manA
Neiella marina J221 STP6, mannokinase, manA
Neptunomonas antarctica S3-22 manP, manA
Nocardioides daejeonensis MJ31 manP, manA
Nocardioides dokdonensis FR1436 manP, manA
Nocardiopsis baichengensis YIM 90130 manP, manA
Nocardiopsis gilva YIM 90087 frcA, frcB, frcC, man-isomerase, scrK
Novosphingobium barchaimii LL02 manP, manA
Novosphingobium fuchskuhlense FNE08-7 manP, manA
Novosphingobium lindaniclasticum LE124 gluP, man-isomerase, scrK
Oceanisphaera arctica V1-41 manP, manA
Ochrobactrum rhizosphaerae PR17 frcA, frcB, frcC, man-isomerase, scrK
Ochrobactrum thiophenivorans DSM 7216 frcA, frcB, frcC, mannokinase, manA
Oscillibacter ruminantium GH1 STP6, man-isomerase, scrK
Paenisporosarcina indica PN2 manP, manA
Palaeococcus pacificus DY20341 manP, manA
Paludibacter propionicigenes WB4 STP6, mannokinase, manA
Pandoraea thiooxydans ATSB16 manP, manA
Pantoea rwandensis LMG 26275 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, mannokinase, manA
Pedobacter arcticus A12 gluP, mannokinase, manA
Photobacterium gaetbulicola Gung47 manP, manA
Photobacterium jeanii R-40508 manP, manA
Phyllobacterium brassicacearum STM 196 frcA, frcB, frcC, man-isomerase, scrK
Phyllobacterium endophyticum PEPV15 frcA, frcB, frcC, man-isomerase, scrK
Phyllobacterium leguminum ORS 1419 frcA, frcB, frcC, man-isomerase, scrK
Planktomarina temperata RCA23 frcA, frcB, frcC, man-isomerase, scrK
Planococcus halocryophilus Or1 manP, manA
Pleomorphomonas diazotrophica R5-392 frcA, frcB, frcC, mannokinase, manA
Polaribacter dokdonensis DSW-5 gluP, man-isomerase, scrK
Pontibacillus litoralis JSM 072002 manP, manA
Pontibacter lucknowensis DM9 manP, manA
Pontibacter ramchanderi LP43 manP, manA
Pontimonas salivibrio CL-TW6 manP, manA
Porphyrobacter dokdonensis DSW-74 gluP, man-isomerase, scrK
Pseudoalteromonas arctica A 37-1-2 gluP, man-isomerase, scrK
Pseudomonas baetica a390 manP, manA
Pseudomonas litoralis 2SM5 manP, manA
Pseudomonas taeanensis MS-3 manP, manA
Pseudovibrio axinellae Ad2 STP6, mannokinase, manA
Psychrobacter arcticus 273-4 manP, manA
Psychrobacter cryohalolentis K5 manP, manA
Psychromonas ingrahamii 37 manP, manA
Psychromonas ossibalaenae JAMM 0738 manP, manA
Rhizobium freirei PRF 81 frcA, frcB, frcC, man-isomerase, scrK
Rhizobium grahamii CCGE 502 frcA, frcB, frcC, man-isomerase, scrK
Rhizobium subbaraonis JC85 frcA, frcB, frcC, man-isomerase, scrK
Rhodanobacter denitrificans 2APBS1 gluP, man-isomerase, scrK
Rhodobacter johrii JA192 frcA, frcB, frcC, man-isomerase, scrK
Rhodobacter maris JA276 manP, manA
Rhodobacter ovatus JA234 frcA, frcB, frcC, man-isomerase, scrK
Rhodobacter viridis JA737 manP, manA
Rhodococcus qingshengii djl-6-2 manP, manA
Rhodopseudomonas pseudopalustris DSM 123 manP, manA
Roseateles aquatilis CCUG 48205 manP, manA
Roseivirga spongicola UST030701-084 STP6, mannokinase, manA
Rubrivirga marina SAORIC-28 gluP, mannokinase, manA
Ruegeria conchae TW15 frcA, frcB, frcC, man-isomerase, scrK
Saccharomonospora marina XMU15 manP, manA
Salinicoccus carnicancri Crm manP, manA
Serinicoccus profundi MCCC 1A05965 manP, manA
Shewanella halifaxensis HAW-EB4 manP, manA
Skermanella stibiiresistens SB22 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, mannokinase, manA
Snodgrassella alvi wkB2 manP, manA
Sphaerochaeta globosa Buddy manP, manA
Sphaerochaeta pleomorpha Grapes TT_C0211, TT_C0327, TT_C0326, TT_C0328, mannokinase, manA
Sphingobium baderi LL03 manP, manA
Sphingobium czechense LL01 gluP, man-isomerase, scrK
Sphingobium quisquiliarum P25 manP, manA
Sphingomonas histidinilytica UM2 manP, manA
Sphingomonas indica Dd16 manP, manA
Sphingomonas laterariae LNB2 manP, manA
Sphingopyxis indica DS15 gluP, man-isomerase, scrK
Sphingopyxis terrae UI2 manP, manA
Sporolactobacillus vineae SL153 manX, manY, manZ, manA
Streptacidiphilus oryzae TH49 manP, manA
Streptococcus anginosus CCUG 39159 manX, manY, manZ, manA
Streptococcus massiliensis 4401825 manX, manY, manZ, manA
Streptococcus oralis 7747 manX, manY, manZ, manA
Streptococcus oralis AZ_3a manX, manY, manZ, manA
Streptomyces kebangsaanensis SUK12 manP, manA
Succinatimonas hippei YIT 12066 HSERO_RS03635, HSERO_RS03640, HSERO_RS03645, mannokinase, manA
Sulfurimonas gotlandica GD1 manP, manA
Tatumella morbirosei LMG 23360 manX, manY, manZ, manA
Thauera humireducens SgZ-1 STP6, mannokinase, manA
Thermoactinomyces daqus H-18 manP, manA
Thermobifida halotolerans YIM 90462 manP, manA
Thermodesulfovibrio aggregans TGE-P1 manP, manA
Thermophagus xiamenensis HS1 STP6, mannokinase, manA
Thermovenabulum gondwanense R270 manP, manA
Thioclava dalianensis DLFJ1-1 frcA, frcB, frcC, man-isomerase, scrK
Thiohalospira halophila HL 3 manP, manA
Tistlia consotensis USBA 355 frcA, frcB, frcC, mannokinase, manA
Vagococcus penaei CD276 manX, manY, manZ, manA
Verminephrobacter eiseniae EF01-2 frcA, frcB, frcC, man-isomerase, scrK
Weissella oryzae SG25 manX, manY, manZ, manA
Williamsia sterculiae CPCC 203464 manP, manA
Yersinia intermedia Y228 manX, manY, manZ, manA

Confidence: high confidence medium confidence low confidence
transporter – transporters and PTS systems are shaded because predicting their specificity is particularly challenging.

This GapMind analysis is from Sep 24 2021. The underlying query database was built on Sep 17 2021.

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About GapMind

Each pathway is defined by a set of rules based on individual steps or genes. Candidates for each step are identified by using ublast (a fast alternative to protein BLAST) against a database of manually-curated proteins (most of which are experimentally characterized) or by using HMMer with enzyme models (usually from TIGRFam). Ublast hits may be split across two different proteins.

A candidate for a step is "high confidence" if either:

where "other" refers to the best ublast hit to a sequence that is not annotated as performing this step (and is not "ignored").

Otherwise, a candidate is "medium confidence" if either:

Other blast hits with at least 50% coverage are "low confidence."

Steps with no high- or medium-confidence candidates may be considered "gaps." For the typical bacterium that can make all 20 amino acids, there are 1-2 gaps in amino acid biosynthesis pathways. For diverse bacteria and archaea that can utilize a carbon source, there is a complete high-confidence catabolic pathway (including a transporter) just 38% of the time, and there is a complete medium-confidence pathway 63% of the time. Gaps may be due to:

GapMind relies on the predicted proteins in the genome and does not search the six-frame translation. In most cases, you can search the six-frame translation by clicking on links to Curated BLAST for each step definition (in the per-step page).

For more information, see:

If you notice any errors or omissions in the step descriptions, or any questionable results, please let us know

by Morgan Price, Arkin group, Lawrence Berkeley National Laboratory