Curated BLAST for Genomes

 

Curated BLAST

Searching in Pandoraea thiooxydans ATSB16 (GCF_001931675.1)

Found 21 curated entries in PaperBLAST's database that match '1.2.1.79' as complete word(s).

These curated entries have 14 distinct sequences.

Running ublast with E ≤ 0.01

Found 19 relevant proteins in Pandoraea thiooxydans ATSB16, or try another query

PATSB16_RS01900 PATSB16_03900 WP_206093660.1: NAD-dependent succinate-semialdehyde dehydrogenase
is similar to:
PaperBLAST

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

67% id,
100% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

63% id,
99% cov

A0A0D5YDF1: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Acinetobacter baumannii

60% id,
94% cov

More...

PATSB16_RS01105 PATSB16_02230 WP_083566633.1: NAD-dependent succinate-semialdehyde dehydrogenase
is similar to:
PaperBLAST

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

62% id,
100% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

62% id,
99% cov

A0A0D5YDF1: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Acinetobacter baumannii

59% id,
94% cov

More...

PATSB16_RS06130 PATSB16_12900 WP_047213175.1: NAD-dependent succinate-semialdehyde dehydrogenase
is similar to:
PaperBLAST

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

47% id,
99% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

49% id,
94% cov

A0A0D5YDF1: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Acinetobacter baumannii

47% id,
94% cov

More...

PATSB16_RS11430 PATSB16_24410 WP_047214246.1: NAD-dependent succinate-semialdehyde dehydrogenase
is similar to:
PaperBLAST

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

41% id,
99% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

42% id,
97% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

42% id,
96% cov

More...

PATSB16_RS01895 PATSB16_03890 WP_047212377.1: NAD-dependent succinate-semialdehyde dehydrogenase
is similar to:
PaperBLAST

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

40% id,
98% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

41% id,
96% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

40% id,
97% cov

More...

hpaE PATSB16_RS08675 PATSB16_18390 WP_047213787.1: 5-carboxymethyl-2-hydroxymuconate semialdehyde dehydrogenase
is similar to:
PaperBLAST

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

40% id,
97% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

39% id,
93% cov

A0A0D5YDF1: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Acinetobacter baumannii

35% id,
98% cov

More...

PATSB16_RS14485 PATSB16_30930 WP_047214813.1: aldehyde dehydrogenase
is similar to:
PaperBLAST

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

38% id,
100% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

39% id,
96% cov

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

36% id,
98% cov

More...

PATSB16_RS09910 PATSB16_21120 WP_047213986.1: aldehyde dehydrogenase family protein
is similar to:
PaperBLAST

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

38% id,
99% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

39% id,
96% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

38% id,
96% cov

More...

PATSB16_RS01930 PATSB16_03970 WP_047212384.1: aldehyde dehydrogenase family protein
is similar to:
PaperBLAST

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

37% id,
99% cov

Q97XA5: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79); glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) from Saccharolobus solfataricus

36% id,
98% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

36% id,
97% cov

More...

phnY PATSB16_RS16135 PATSB16_34450 WP_047215084.1: phosphonoacetaldehyde dehydrogenase
is similar to:
PaperBLAST

Q97XA5: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79); glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) from Saccharolobus solfataricus

36% id,
99% cov

GABD1_MYCTU / P9WNX9: Succinate-semialdehyde dehydrogenase [NADP(+)] 1; SSADH 1; SSDH 1; EC 1.2.1.79 from Mycobacterium tuberculosis
gabD1 / P9WNX9: NADP-dependent succinate-semialdehyde dehydrogenase (EC 1.2.1.79) from Mycobacterium tuberculosis
P9WNX9: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Mycobacterium tuberculosis

36% id,
99% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

36% id,
97% cov

More...

PATSB16_RS03895 PATSB16_08170 WP_047212725.1: aldehyde dehydrogenase family protein
is similar to:
PaperBLAST

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

36% id,
98% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

36% id,
94% cov

Q55585: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Synechocystis sp.

34% id,
100% cov

More...

adh PATSB16_RS15895 PATSB16_33920 WP_047215047.1: aldehyde dehydrogenase
is similar to:
PaperBLAST

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

35% id,
97% cov

A0A0D5YDF1: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Acinetobacter baumannii

35% id,
96% cov

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

34% id,
98% cov

More...

PATSB16_RS19035 PATSB16_40540 WP_047216758.1: CoA-acylating methylmalonate-semialdehyde dehydrogenase
is similar to:
PaperBLAST

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

36% id,
95% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

34% id,
94% cov

GABD1_MYCTU / P9WNX9: Succinate-semialdehyde dehydrogenase [NADP(+)] 1; SSADH 1; SSDH 1; EC 1.2.1.79 from Mycobacterium tuberculosis
gabD1 / P9WNX9: NADP-dependent succinate-semialdehyde dehydrogenase (EC 1.2.1.79) from Mycobacterium tuberculosis
P9WNX9: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Mycobacterium tuberculosis

32% id,
98% cov

More...

PATSB16_RS02595 PATSB16_05350 WP_237170284.1: aldehyde dehydrogenase
is similar to:
PaperBLAST

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

34% id,
98% cov

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

33% id,
99% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

34% id,
97% cov

More...

PATSB16_RS19575 PATSB16_41650 WP_047215662.1: aldehyde dehydrogenase family protein
is similar to:
PaperBLAST

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

32% id,
98% cov

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

31% id,
94% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

30% id,
96% cov

More...

putA PATSB16_RS19600 PATSB16_41710 WP_047215665.1: trifunctional transcriptional regulator/proline dehydrogenase/L-glutamate gamma-semialdehyde dehydrogenase
is similar to:
PaperBLAST

gabD / Q9RBF6: NADP-dependent succinate semialdehyde dehydrogenase (EC 1.2.1.79) from Cupriavidus necator
Q9RBF6: succinate-semialdehyde dehydrogenase [NAD(P)+] (EC 1.2.1.16); succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Cupriavidus necator

32% id,
97% cov

GABD_ECOLI / P25526: Succinate-semialdehyde dehydrogenase [NADP(+)] GabD; SSDH; Glutarate-semialdehyde dehydrogenase; EC 1.2.1.79; EC 1.2.1.- from Escherichia coli
GabD / b2661: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79) from Escherichia coli
gabD / P25526: succinate-semialdehyde dehydrogenase (NADP+) GabD (EC 1.2.1.79; EC 1.2.1.20) from Escherichia coli
P25526: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Escherichia coli

32% id,
95% cov

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

31% id,
97% cov

More...

PATSB16_RS18235 PATSB16_38890 WP_047215452.1: coniferyl aldehyde dehydrogenase
is similar to:
PaperBLAST

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

31% id,
95% cov

sad / Q8GAK7: succinate-semialdehyde dehydrogenase (NADP+) monomer (EC 1.2.1.79) from Paenarthrobacter nicotinovorans

29% id,
95% cov

A0A1Q6BLU5: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Corynebacterium glutamicum

27% id,
94% cov

More...

PATSB16_RS09530 PATSB16_20260 WP_047213921.1: 3,4-dehydroadipyl-CoA semialdehyde dehydrogenase
is similar to:
PaperBLAST

A0A0D5YDF1: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79) from Acinetobacter baumannii

26% id,
90% cov

PATSB16_RS14005 PATSB16_29910 WP_047214736.1: aldehyde dehydrogenase family protein
is similar to:
PaperBLAST

Q97XA5: succinate-semialdehyde dehydrogenase (NADP+) (EC 1.2.1.79); glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) from Saccharolobus solfataricus

22% id,
81% cov

GABD_BACSU / P94428: Succinate-semialdehyde dehydrogenase [NADP(+)]; SSDH; EC 1.2.1.79 from Bacillus subtilis

23% id,
60% cov

The hits are sorted by %identity * %coverage (highest first)

Running ublast against the 6-frame translation. All reading frames of at least 30 codons are included.

Found hits to 17 reading frames. These were all redundant with annotated proteins.

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory