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Align G3V9P7 to PF12372 (Htt_N-HEAT)

G3V9P7 has 3120 amino acids

Query:       Htt_N-HEAT  [M=851]
Accession:   PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
          0 1134.9   4.5          0 1134.9   4.5    1.6  2  G3V9P7    


Domain annotation for each sequence (and alignments):
>> G3V9P7  
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -3.7   0.1      0.15      0.15      65      99 ..     118     163 ..      86     260 .. 0.51
   2 ! 1134.9   4.5         0         0       1     850 [.     737    1612 ..     737    1613 .. 0.98

  Alignments for each domain:
  == domain 1  score: -3.7 bits;  conditional E-value: 0.15
  Htt_N-HEAT  65 ssgtlrlaisavesClrn....LadSkeflqlLqllie..........l 99 
                    ++r+     + Cl++    L+dS+   + L+l  e           
      G3V9P7 118 AESDVRM---VADECLNKvikaLMDSNLPRLQLELYKEikkngaprslR 163
                 4455666...335555555555667766666666666544444444441 PP

  == domain 2  score: 1134.9 bits;  conditional E-value: 0
  Htt_N-HEAT    1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqlli 97  
                  y +h Dpq+rg++++l++++++++ls+++l++++wl ++++ ++ ++++l +++ ll+k+Lkdess+t++la++av++C+ +L++S++++++Lqlli
      G3V9P7  737 YIDHGDPQVRGATAILCGTLVYSILSRSRLRVGDWLGTIRALTG-NTFSLVDCIPLLQKTLKDESSVTCKLACTAVRHCVLSLCSSSYSDLGLQLLI 832 
                  679***************************************99.9*************************************************** PP

  Htt_N-HEAT   98 ellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.eed 179 
                  ++l lk+s+ywlv++elle+la+++++lv+              ++t++ +lqervl++v+i+ll+dedprvr++aa+++++++pkLfyk+++ ++d
      G3V9P7  833 DMLPLKNSSYWLVRTELLETLAEIDFRLVSfleakaeslhrgahHYTGFLKLQERVLNNVVIYLLGDEDPRVRHVAATTLTRLVPKLFYKCDQgQAD 929 
                  ************************************************************************************************* PP

  Htt_N-HEAT  180 eitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsleypva 274 
                   ++a+A+++s+ +l+ l++ ++   sh   s+i++++++yslL +      t+ ++e++lSr+v+++s++L++s+++al++gC+eal++ls+++pv+
      G3V9P7  930 PVVAVARDQSSVYLKLLMHETQP-PSHFsvSTITRIYRGYSLLPS-----VTDVTMENNLSRVVAAVSHELITSTTRALTFGCCEALCVLSAAFPVC 1020
                  ******************66644.33335799*************.....7999******************************************* PP

  Htt_N-HEAT  275 lyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik...lsdsepsk........Wdals 360 
                  +++ +W+c v+      + +a+des++++++g++s++l+LLss+++++dl+aH+d+LilagnLla++a ++++   +s++e+s+        W+al 
      G3V9P7 1021 TWSLGWHCGVP------PLSASDESRKSCTVGMASMILTLLSSAWFPLDLSAHQDALILAGNLLAASAPKSLRsswASEEEGSSaatrqeeiWPALG 1111
                  **********8......99******************************************************99999***9999************ PP

  Htt_N-HEAT  361 dtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqssparngi...............va 442 
                  d++lv+++eql++h+l+++ni+a+vlddvtpg+a+k+alpsl+++++lSp++r    + kekep+e++++ ++sp++ g+               ++
      G3V9P7 1112 DRTLVPMVEQLFSHLLKVINICAHVLDDVTPGPAIKAALPSLTNPPSLSPIRR----KGKEKEPGEQTST-PMSPKKGGEastasrqsdtsgpvtAS 1203
                  *****************************************************....9***********8.9******99**************99* PP

  Htt_N-HEAT  443 kkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvqqLLksL 539 
                  k++slGsF+h+p+ylrl+++Lka+++nYkvtL+ +++++kf ++L+++L+v+sq+lelAtlq++gk++eevL+ylk+++++ep++++ cvqqLLk+L
      G3V9P7 1204 KSSSLGSFYHLPSYLRLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILELATLQDIGKCVEEVLGYLKSCFSREPMMATVCVQQLLKTL 1300
                  ************************************************************************************************* PP

  Htt_N-HEAT  540 FgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvarklaavlk 627 
                  FgtNlas+++     psk+++r++R   ++s+   ++g+yh++f++P++++++al  a++s  ++vqa++e++   w+++l+k+s++ +++l++v+k
      G3V9P7 1301 FGTNLASQFDglssnPSKSQCRAQR-LGSSSV---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQADQEHDasgWFDVLQKVSAQLKTNLTSVTK 1391
                  *************************.889999...9*******************..8988889*****************************9999 PP

  Htt_N-HEAT  628 gvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiFqFLvlLSy 724 
                   +r+d+++i+n+IRlfE+lvik+LkqYt+t+sv+lqkqvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+rese++ip+iF+FLvlLSy
      G3V9P7 1392 -NRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSY 1487
                  .9*********************************************************************************************** PP

  Htt_N-HEAT  725 eryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellilildscrveaneek 821 
                  eryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q+evv+++LlrL++yh+v+e++il+l++c++e ne+k
      G3V9P7 1488 ERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKE-NEDK 1583
                  ********************************************************************************************.**** PP

  Htt_N-HEAT  822 wkrasrqvadvvLpllaklkisldsthql 850 
                  wkr+srqvad++Lp+lak+++++ds+++l
      G3V9P7 1584 WKRLSRQVADIILPMLAKQQMHIDSHEAL 1612
                  ***************************97 PP



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