G3X9H5 has 3120 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
0 1125.6 6.2 0 1125.6 6.2 1.7 2 G3X9H5
Domain annotation for each sequence (and alignments):
>> G3X9H5
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.3 0.1 0.11 0.11 65 165 .. 119 256 .. 86 291 .. 0.52
2 ! 1125.6 6.2 0 0 1 850 [. 737 1612 .. 737 1613 .. 0.98
Alignments for each domain:
== domain 1 score: -3.3 bits; conditional E-value: 0.11
Htt_N-HEAT 65 ssgtlrlaisavesClrn....LadSkeflqlLqllie.............llalktsaywlvkvell..ellaklkyvlve................. 127
++r+ + Cl++ L+dS+ + L+l e l + lv+ + + +l++ l+ + +
G3X9H5 119 AESDVRM---VADECLNKvikaLMDSNLPRLQLELYKEikkngaprslraaL-WRFAELAHLVRPQKCrpYLVNLLPCLTRTskrpeesvqetlaaavp 213
4456666...345555555555777776666666666655555555444321.1122222344444443334444444444433333333333333333 PP
Htt_N-HEAT 128 .......nitassrlqervldsvliallqdedprvrsaaaaaivk 165
n +++ +vl ++ ia l+ p vr++aa v+
G3X9H5 214 kimasfgNFANDNEI--KVLLKAFIANLKSSSPTVRRTAAGSAVS 256
333333322222222..2224455555555555555555555554 PP
== domain 2 score: 1125.6 bits; conditional E-value: 0
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqlli 97
y +h Dpq+rg++++l++++++++ls+++l++++wl ++++ ++ ++++l +++ ll+k+Lkdess+t++la++av++C+ +L++S++++++Lqlli
G3X9H5 737 YIDHGDPQVRGATAILCGTLVYSILSRSRLRVGDWLGNIRTLTG-NTFSLVDCIPLLQKTLKDESSVTCKLACTAVRHCVLSLCSSSYSDLGLQLLI 832
679***************************************99.9*************************************************** PP
Htt_N-HEAT 98 ellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.eed 179
++l lk+s+ywlv++ell++la+++++lv+ ++t++ +lqervl++v+i+ll+dedprvr++aa+ +++++pkLfyk+++ ++d
G3X9H5 833 DMLPLKNSSYWLVRTELLDTLAEIDFRLVSfleakaeslhrgahHYTGFLKLQERVLNNVVIYLLGDEDPRVRHVAATSLTRLVPKLFYKCDQgQAD 929
************************************************************************************************* PP
Htt_N-HEAT 180 eitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsleypva 274
++a+A+++s+ +l+ l++ ++ sh s+i++++++yslL + t+ ++e++lSr+v+++s++L++s+++al++gC+eal+ ls+++pv+
G3X9H5 930 PVVAVARDQSSVYLKLLMHETQP-PSHFsvSTITRIYRGYSLLPS-----ITDVTMENNLSRVVAAVSHELITSTTRALTFGCCEALCLLSAAFPVC 1020
******************66644.33335799*************.....6888******************************************* PP
Htt_N-HEAT 275 lyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik...lsdsepsk........Wdals 360
+++ +W+c v+ + +a+des++++++g++s++l+LLss+++++dl+aH+d+LilagnLla++a ++++ +s++e + W+al
G3X9H5 1021 TWSLGWHCGVP------PLSASDESRKSCTVGMASMILTLLSSAWFPLDLSAHQDALILAGNLLAASAPKSLRsswTSEEEANSaatrqeeiWPALG 1111
**********8......99******************************************************999999987778999********* PP
Htt_N-HEAT 361 dtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqssparngi...............va 442
d++lv+l+eql++h+l+++ni+a+vlddvtpg+a+k+alpsl+++++lSp++r + kekep+e+ ++ ++sp++ g+ ++
G3X9H5 1112 DRTLVPLVEQLFSHLLKVINICAHVLDDVTPGPAIKAALPSLTNPPSLSPIRR----KGKEKEPGEQAST-PMSPKKVGEasaasrqsdtsgpvtAS 1203
*****************************************************....9********9998.9***99999**************99* PP
Htt_N-HEAT 443 kkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvqqLLksL 539
k++slGsF+h+p+yl+l+++Lka+++nYkvtL+ +++++kf ++L+++L+v+sq+lelAtlq++gk++eevL+ylk+++++ep++++ cvqqLLk+L
G3X9H5 1204 KSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILELATLQDIGKCVEEVLGYLKSCFSREPMMATVCVQQLLKTL 1300
************************************************************************************************* PP
Htt_N-HEAT 540 FgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvarklaavlk 627
FgtNlas+++ psk+++r++R ++s+ ++g+yh++f++P++++++al a++s ++vqae+e + w+++l+k+s++ +++l++v+k
G3X9H5 1301 FGTNLASQFDglssnPSKSQCRAQR-LGSSSV---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAEQERDasgWFDVLQKVSAQLKTNLTSVTK 1391
*************************.889999...9*******************..8888889******99999******************9999 PP
Htt_N-HEAT 628 gvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiFqFLvlLSy 724
+r+d+++i+n+IRlfE+lvik+LkqYt+t+sv+lqkqvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+rese++ip+iF+FLvlLSy
G3X9H5 1392 -NRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSY 1487
.9*********************************************************************************************** PP
Htt_N-HEAT 725 eryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellilildscrveaneek 821
eryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q+evv+++LlrL++yh+v+e++il+l++c++e ne+k
G3X9H5 1488 ERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKE-NEDK 1583
********************************************************************************************.**** PP
Htt_N-HEAT 822 wkrasrqvadvvLpllaklkisldsthql 850
wkr+srqvad++Lp+lak+++++ds+++l
G3X9H5 1584 WKRLSRQVADIILPMLAKQQMHIDSHEAL 1612
***************************97 PP
Or compare G3X9H5 to CDD or PaperBLAST