NP_002102.4 has 3144 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
0 1096.4 5.6 0 1095.2 5.6 1.6 1 NP_002102.4
Domain annotation for each sequence (and alignments):
>> NP_002102.4
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 1095.2 5.6 0 0 1 850 [. 758 1633 .. 758 1634 .. 0.97
Alignments for each domain:
== domain 1 score: 1095.2 bits; conditional E-value: 0
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqll 96
y +h Dpq+rg++++l++++i ++ls+++ ++++w+ ++++ ++ ++++l +++ ll k+Lkdess+t++la++av+ C+ +L++S++++++Lql+
NP_002102.4 758 YIDHGDPQVRGATAILCGTLICSILSRSRFHVGDWMGTIRTLTG-NTFSLADCIPLLRKTLKDESSVTCKLACTAVRNCVMSLCSSSYSELGLQLI 852
679***************************************99.9************************************************** PP
Htt_N-HEAT 97 iellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.e 177
i++l l +s+ywlv++elle+la+++++lv+ ++t+ +lqervl++v+i+ll+dedprvr++aaa +++++pkLfyk+++ +
NP_002102.4 853 IDVLTLRNSSYWLVRTELLETLAEIDFRLVSfleakaenlhrgahHYTGLLKLQERVLNNVVIHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQgQ 948
************************************************************************************************ PP
Htt_N-HEAT 178 edeitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsley 271
+d ++a+A+++s+ +l+ l++ ++ sh s+i++++++y lL + t+ ++e++lSr+++++s++L++s+++al++gC+eal+ ls ++
NP_002102.4 949 ADPVVAVARDQSSVYLKLLMHETQP-PSHFsvSTITRIYRGYNLLPS-----ITDVTMENNLSRVIAAVSHELITSTTRALTFGCCEALCLLSTAF 1038
********************66644.33335799*************.....6888**************************************** PP
Htt_N-HEAT 272 pvalyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik...lsdsepsk........W 356
pv+ ++ +W+c v+ + +a+des++++++g++ ++l+LLss+++++dl+aH+d+LilagnLla++a ++++ +s++e W
NP_002102.4 1039 PVCIWSLGWHCGVP------PLSASDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDALILAGNLLAASAPKSLRsswASEEEANPaatkqeevW 1128
*************8......99******************************************************998777765446788999** PP
Htt_N-HEAT 357 dalsdtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqssparngi............ 440
+al d+ lv+++eql++h+l+++ni+a+vlddv+pg+a+k+alpsl+++++lSp++r + kekep+e+ + + sp++ +
NP_002102.4 1129 PALGDRALVPMVEQLFSHLLKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRR----KGKEKEPGEQASV-PLSPKKGSEasaasrqsdtsg 1219
*********************************************************....9********9996.8888777778889999999** PP
Htt_N-HEAT 441 ...vakkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvq 533
++k++slGsF+h+p+yl+l+++Lka+++nYkvtL+ +++++kf ++L+++L+v+sq+lelAtlq++gk++ee+L+ylk+++++ep++++ cvq
NP_002102.4 1220 pvtTSKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQ 1315
*999******************************************************************************************** PP
Htt_N-HEAT 534 qLLksLFgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvar 620
qLLk+LFgtNlas+++ psk++ r++R ++s+ ++g+yh++f++P++++++al a++s ++vqae+e++ w+++l+k+s + ++
NP_002102.4 1316 QLLKTLFGTNLASQFDglssnPSKSQGRAQR-LGSSSV---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAEQENDtsgWFDVLQKVSTQLKT 1405
*******************************.889999...9*******************..8888889********99**************** PP
Htt_N-HEAT 621 klaavlkgvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiF 716
+l++v+k +r+d+++i+n+IRlfE+lvik+LkqYt+t+ v+lqkqvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+rese++ip+iF
NP_002102.4 1406 NLTSVTK-NRADKNAIHNHIRLFEPLVIKALKQYTTTTCVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIF 1500
***9999.9*************************************************************************************** PP
Htt_N-HEAT 717 qFLvlLSyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellililds 812
+FLvlLSyeryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q+evv+++LlrL++yh+v+e++il+l++
NP_002102.4 1501 FFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQ 1596
************************************************************************************************ PP
Htt_N-HEAT 813 crveaneekwkrasrqvadvvLpllaklkisldsthql 850
c++e ne+kwkr+srq+ad++Lp+lak+++++ds+++l
NP_002102.4 1597 CHKE-NEDKWKRLSRQIADIILPMLAKQQMHIDSHEAL 1633
****.*******************************97 PP
Or compare NP_002102.4 to CDD or PaperBLAST