NP_571093.1 has 3121 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
0 1018.6 5.3 0 1017.6 5.3 1.5 1 NP_571093.1
Domain annotation for each sequence (and alignments):
>> NP_571093.1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 1017.6 5.3 0 0 1 850 [. 708 1605 .. 708 1606 .. 0.95
Alignments for each domain:
== domain 1 score: 1017.6 bits; conditional E-value: 0
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqll 96
y +h D q+rg++++l++ +i+a+ +++++ e wl++++s ++ ++++l+++v ll++ Lkdess+t+++a+ av++C+ L++ + ++++Lqll
NP_571093.1 708 YIEHGDHQIRGATAILCGALIQAIQLKTRYNTETWLSQIQSVTG-SSVTLENFVPLLQRSLKDESSVTCKMACAAVRHCIMALCNGSLSELGLQLL 802
679****************************************9.99************************************************* PP
Htt_N-HEAT 97 iellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.e 177
i+ll lk+ +ywlv++elle+la+++++l++ ++t+ rlq+rvl++v+++ll+dedprvr++aa++i +++p+Lf+ +++ +
NP_571093.1 803 IDLLTLKNCSYWLVRTELLETLAEIDFRLISflerkteklhkgehHYTGLLRLQDRVLNDVVLYLLGDEDPRVRHVAANTIGRLVPRLFFDCDQgQ 898
************************************************************************************************ PP
Htt_N-HEAT 178 edeitakAkelsekllscltellveleshd...slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsle 270
d ++a A+++s+ l+ l++ ++ ++ s+i++ ++++ l ++ + ++e++lSr+++++s+ L+ s+s+a+++gC+eal+ ls +
NP_571093.1 899 TDPVVAIARDQSSVHLQLLMHETQPP--SQftvSTITRTYRGFNLCQS-----APDVTVENNLSRVITAISHALTSSTSRAMTFGCCEALCLLSST 987
*******************9655332..33334666666666666666.....7788*************************************** PP
Htt_N-HEAT 271 ypvalyekaWgckv.........ksklkrd...........asvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrni 346
+pv+ ++++W+c +s + s ++e + + ++g++s+vlsL+ss+++++dl+aH+ +L+lagnLla++a + +
NP_571093.1 988 FPVCNWSTGWHCGFvsssvfhlnRSS---QyrsrgrsfslsQSGSNEEVRRSLTVGVASMVLSLISSAWFPLDLSAHQAALLLAGNLLAAVAPKCM 1080
************98899988776333...13346788998878889999*********************************************** PP
Htt_N-HEAT 347 k..lsdsepsk.........WdalsdtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarr 431
k +++e+s+ W+al+d+ lv ++eql++h+l++lni+a+vldd +pg+a k+ lpsl+++++lSp++r + kek +e ++
NP_571093.1 1081 KspWAGEEESSpasskveepWPALNDRSLVVMVEQLFSHLLKILNICAHVLDDTPPGPAVKASLPSLANTPSLSPIRR----KGKEKDMMEAGTT- 1171
*995555555558899**************************************************************....8899999997775. PP
Htt_N-HEAT 432 qssparngi..............vakkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeev 513
++sp++ g+ v+k+ +lGsF+h+p yl+ly+ L+a+++nYkvtL+ + ++kf ++L+++L+v+sqllelAtl+++gk++ee+
NP_571093.1 1172 PMSPKKGGEtntgraadstataaVNKSTTLGSFYHLPPYLKLYDALRATHANYKVTLDLHNPNEKFGGFLRSALDVLSQLLELATLHDIGKCVEEI 1267
99999999999999********9************************************************************************* PP
Htt_N-HEAT 514 LmylkleiqsepkatvrcvqqLLksLFgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaee 603
L+ylk+++++ep++++ cvqqLLk+LFgtNlas+++ p +++ ++lR ++s+ ++g+yh++f++P++++++al a++s ++vqae+
NP_571093.1 1268 LGYLKSCFSREPTMATVCVQQLLKALFGTNLASQYEgassnPCRSQGKALR-LGSSSV---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAEQ 1357
***********************************9988887888888888.678888...9*******************..8888889*****9 PP
Htt_N-HEAT 604 eae...wlgllkkkslkvarklaavlkgvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkq 696
e++ w+++++k+s + + +++v+ r d+++i+n+IRlfE+lvik+LkqYt+ +sv+lq+qvl+LLaqLvqlrvnyclldsdqvfigfvLkq
NP_571093.1 1358 EQDasgWFDVMQKVSNQLRSSITNVTR-HRGDKNAIHNHIRLFEPLVIKALKQYTTSTSVALQRQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQ 1452
99999******************9988.9******************************************************************* PP
Htt_N-HEAT 697 feyiEeGqvresedlipkiFqFLvlLSyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlak 792
feyiE+Gq+r+se+++p+iF+FLvlLSyeryhsk+ii ipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+s+ka+++kele+q+evv+++
NP_571093.1 1453 FEYIEVGQFRDSEEIVPNIFFFLVLLSYERYHSKQIISIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGSNKADAGKELETQKEVVVSM 1548
************************************************************************************************ PP
Htt_N-HEAT 793 LlrLleyhevvellilildscrveaneekwkrasrqvadvvLpllaklkisldsthql 850
LlrL+++h+v+e++il+l++c++e ne+kwkr+srqvad++Lp+++k++++lds+++l
NP_571093.1 1549 LLRLIQHHQVLEMFILVLQQCHKE-NEDKWKRLSRQVADIILPMIGKQQMHLDSHEAL 1605
************************.*******************************97 PP
Or compare NP_571093.1 to CDD or PaperBLAST