O60303 has 1618 amino acids
Query: DUF4457 [M=323]
Accession: PF14652.10
Description: Domain of unknown function (DUF4457)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7.8e-206 668.6 0.0 1.8e-155 503.1 0.0 4.2 4 O60303
Domain annotation for each sequence (and alignments):
>> O60303
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 22.9 0.1 2.4e-09 2.4e-09 177 322 .. 464 606 .. 430 607 .. 0.69
2 ! 20.7 0.1 1.1e-08 1.1e-08 2 135 .. 482 606 .. 481 654 .. 0.65
3 ! 136.2 0.0 7.9e-44 7.9e-44 2 155 .. 980 1131 .. 979 1144 .. 0.93
4 ! 503.1 0.0 1.8e-155 1.8e-155 1 322 [. 1214 1532 .. 1214 1533 .. 0.98
Alignments for each domain:
== domain 1 score: 22.9 bits; conditional E-value: 2.4e-09
DUF4457 177 vsqdyeapllpsgfvlklqllstwGDkyyiGLnglelydekgekikltesniaalpesvnvldevsgdvrtpdklidgvnntlddrhmwlapilpglvnkiy 278
+q +a+ + + + +++ls+wG ++GL +e++d +++k+ + +p++v + ++++ + +l++ d+ w p p+l +
O60303 464 DKQRMRADEIKDAIYVTMEILSNWGNSWWVGLTEVEFFDLNDTKLYV-------SPHDVDIRNTATP--GELGRLVNRNLAGKKDSSPWTCPFHPPLQLFFV 556
44555667777888889999999999999999999999999988844.......5666664443333..345566666666666777799998888755433 PP
DUF4457 279 vifde...PvtvsmiklWNYsktp...srgvkeleilvDDlliykGilkk 322
+ + + +++ik+ NY g k+++++v li++G l+k
O60303 557 IRNTRqlgDFHLAKIKVRNYWTADgdlDIGAKNVKLYVNRNLIFNGKLDK 606
33322223478999999999876422267999999999999999999986 PP
== domain 2 score: 20.7 bits; conditional E-value: 1.1e-08
DUF4457 2 nllstWgDsyylGLtglevldeegkaiplqlenikakprdlndlpeysgdkrtldklidgtnvttddehmwlipfsegkehvltidfkke...ksisglriw 100
++ls+Wg+s+ +GLt +e++d + +++ ++ + ++++ + +l +l++ +d+ w+ pf++ + + i+ +++ +++++++
O60303 482 EILSNWGNSWWVGLTEVEFFDLNDTKLYVSPHDVDIRN---------TATPGELGRLVNRNLAGKKDSSPWTCPFHPPLQLFFVIRNTRQlgdFHLAKIKVR 574
56778888888888888888877776666655555544.........4456677888887777788888888888887777666665543222578888888 PP
DUF4457 101 NYnksledtfrgakkvsvsldgkslspkegfllrk 135
NY + d gak v+++++ + + + + l k
O60303 575 NYWTADGDLDIGAKNVKLYVNRNLIFNGK---LDK 606
88888888888888888888777766655...444 PP
== domain 3 score: 136.2 bits; conditional E-value: 7.9e-44
DUF4457 2 nllstWgDsyylGLtglevldeegkaiplqlenikakprdlndlpeysgdkrtldklidgtnvttddehmwlipfsegkehvltidfkkeksisglriwN 101
++stWgD++y+GL g+e++ ++g+ p+q++nika+p d+n lp y d r + +lidg+n t dd+h+wl pf++g++h +tidf+++ +++ +riwN
O60303 980 DIKSTWGDRHYVGLNGIEIFSSKGE--PVQISNIKADPPDINILPAYGKDPRVVTNLIDGVNRTQDDMHVWLAPFTRGRSHSITIDFTHPCHVALIRIWN 1077
6899********************9..999********************************************************************** PP
DUF4457 102 YnksledtfrgakkvsvsldgkslspkegfllrkapGnsa...fdfaqtillqeedk 155
Ynks +frg+k +++ ld +++ + e + ka G+ a f++til+++ d
O60303 1078 YNKSRIHSFRGVKDITMLLDTQCIFEGE---IAKASGTLAgapEHFGDTILFTTDDD 1131
**************************99...89999998744356999999987665 PP
== domain 4 score: 503.1 bits; conditional E-value: 1.8e-155
DUF4457 1 lnllstWgDsyylGLtglevldeegkaiplqlenikakprdlndlpeysgdkrtldklidgtnvttddehmwlipfsegkehvltidfkkeksisglriw 100
ln++++WgD +ylGLtglev+++eg+a+p++l++i+a+prdln+lpeys+d+r ldklidgtn+t++dehmwlipfs+g +hv+ti++++++si+glr+w
O60303 1214 LNFTASWGDLHYLGLTGLEVVGKEGQALPIHLHQISASPRDLNELPEYSDDSRALDKLIDGTNITMEDEHMWLIPFSPGLDHVVTIRLDRAESIAGLRFW 1313
79************************************************************************************************** PP
DUF4457 101 NYnksledtfrgakkvsvsldgkslspkegfllrkapGnsafdfaqtillqeedkleeeeksvesklkskskkveevsqdyeapllpsgfvlklqllstw 200
NYnks+edt+rgak+v+vsldg ++sp+egfl+rk+pGn++fdfaq+il+ +d+l++ + + ++ ++ e +s+dyeapl+p+gf++++qll++w
O60303 1314 NYNKSPEDTYRGAKIVHVSLDGLCVSPPEGFLIRKGPGNCHFDFAQEILF--VDYLRA-QLLPQPARRLDMRSLECASMDYEAPLMPCGFIFQFQLLTSW 1410
**************************************************..999999.77777888888999*************************** PP
DUF4457 201 GDkyyiGLnglelydekgekikltesniaalpesvnvldevsgdvrtpdklidgvnntlddrhmwlapilpglvnkiyvifdePvtvsmiklWNYsktps 300
GD+yyiGL glelyde+geki+l+e+niaa+p+svn l++v gdvrtpdklid vn+t d+rhmwlapilpglvn++yvifd P+tvsmiklWNY+ktp+
O60303 1411 GDPYYIGLTGLELYDERGEKIPLSENNIAAFPDSVNSLEGVGGDVRTPDKLIDQVNDTSDGRHMWLAPILPGLVNRVYVIFDLPTTVSMIKLWNYAKTPH 1510
**************************************************************************************************** PP
DUF4457 301 rgvkeleilvDDlliykGilkk 322
rgvke+++lvDDll+y+Gil +
O60303 1511 RGVKEFGLLVDDLLVYNGILAM 1532
********************87 PP
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