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Align O60673 to PF15735 (DUF4683)

O60673 has 3130 amino acids

Query:       DUF4683  [M=411]
Accession:   PF15735.9
Description: Domain of unknown function (DUF4683)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   6.3e-180  585.2  15.2   6.3e-180  585.2  15.2    5.3  5  O60673    


Domain annotation for each sequence (and alignments):
>> O60673  
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -7.8  10.6         1         1      61     229 ..     480     656 ..     473     679 .. 0.58
   2 !  585.2  15.2  6.3e-180  6.3e-180       2     411 .]     747    1133 ..     745    1133 .. 0.97
   3 ?   -5.8   7.3         1         1     318     359 ..    1186    1224 ..    1154    1262 .. 0.53
   4 ?    1.6   2.2      0.01      0.01     295     358 ..    1527    1592 ..    1399    1644 .. 0.79
   5 ?   -2.0   2.5      0.13      0.13      93     181 ..    1692    1780 ..    1689    1815 .. 0.69

  Alignments for each domain:
  == domain 1  score: -7.8 bits;  conditional E-value: 1
  DUF4683  61 nClsrrsalkklvdvtyklqqskkesrlklkkkkknlaekkekee..aedkastkekayiqknalnksisekeevlskdvkvakea....seekalidsans 156
               C ++rs  + +   +++ + s++ +++ ++++ + la+   ++   + d++s  +  + +++ +++s+  +++   k+    k+a    + ++a i+ +  
   O60673 480 HCAKKRSLCRNTHRSSTEDDDSSSGEEMEWSDNSLLLASLSIPQLdgTADENSD-NPLNNENSRTHSSVIATSKLSVKPSIFHKDAatlePSSSAKITFQCK 580
              699999977777888899999999999999999999998876666434444444.45556666666666666666666622222220000222223322222 PP

  DUF4683 157 asvefeddseesedalveikdis....aklstdksssligskYtLRaKRKvnyeteDsessekiqnkkeslpkkrke 229
                + ++ + ++ ed++ + ++      + l+ + +s   +s Y+++    +  +t  se+s k ++kke lp ++ e
   O60673 581 HTSALSSHVLNKEDLIEDLSQTNknteKGLDNSVTSFTNESTYSMKYPGSL-SSTVHSENSHKENSKKEILPVSSCE 656
              334444444555555444444433311333333333333444444433332.3455899999999999888876655 PP

  == domain 2  score: 585.2 bits;  conditional E-value: 6.3e-180
  DUF4683    2 lsseedvdtvvedddestdesdlgkLkiRYEefqenkaektslsqqeahykFFPSVvlsnClsrrsalkklvdvtyklqqskkesrlklkkkkknlaekk 101 
               ls++++++t+v++ ++++des+l+kLkiRYEefqe+k+ek+slsqq+ahy+FFPSVvlsnCl r   ++kl++vtyklq ++k srlkl+k+k  la+++
   O60673  747 LSCSGENRTMVHSLNSTADESGLNKLKIRYEEFQEHKTEKPSLSQQAAHYMFFPSVVLSNCLTR---PQKLSPVTYKLQPGNKPSRLKLNKRK--LAGHQ 841 
               59**************************************************************...*************************9..99999 PP

  DUF4683  102 ekee.aedkastkekayiqknalnksisekeevlskd.vkvakeaseekalidsansasvefeddseesedalveikdisaklstdksssligskYtLRa 199 
               e+++ ++++ st +  +iq+n++n s++ek+++l++d +k +++a+e+k+++d   +++++f d+++e+e++                ++l+g+kYtLRa
   O60673  842 ETSTkSSETGST-KDNFIQNNPCN-SNPEKDNALASDlTKTTRGAFENKTPTDG--FIDCHFGDGTLETEQS----------------FGLYGNKYTLRA 921 
               998845666666.7789*******.99**********99************965..9***************................************ PP

  DUF4683  200 KRKvnyeteDsessekiqnkkeslpkkrkeeedldgskkskKrrKvskkePPviiKYiiiNRFkGrKnmLVKlgkvdssEesVtLteeklekYkKLAPLK 299 
               KRKvnyeteDsess++++n+k+slp+ ++  e+ldg++ks+KrrK+skk+PPviiKYiiiNRF+GrKnmLVKlgk+ds+E++V+Lteek+e+YkKLAPLK
   O60673  922 KRKVNYETEDSESSFVTHNSKISLPHPMEIGESLDGTLKSRKRRKMSKKLPPVIIKYIIINRFRGRKNMLVKLGKIDSKEKQVILTEEKMELYKKLAPLK 1021
               **************************************************************************************************** PP

  DUF4683  300 dFWpkvpdsratkypvysLtpKksqkrKaKvkstkkkrikklkniesknikrtlsf.rkrssailsppqpsysaeaeDcdlnysdvmsklGflserslsp 398 
               dFWpkvpds+atkyp+y+LtpKks++rK+K+ks+kkk++ k+++++++nikrtlsf +krs+ailspp+psy+ae+eDcdlnysdvmsklGflsers+sp
   O60673 1022 DFWPKVPDSPATKYPIYPLTPKKSHRRKSKHKSAKKKTG-KQQRTNNENIKRTLSFrKKRSHAILSPPSPSYNAETEDCDLNYSDVMSKLGFLSERSTSP 1120
               ***************************************.99**************778999************************************** PP

  DUF4683  399 velspPrCwspsd 411 
               +++spPrCwsp+d
   O60673 1121 INSSPPRCWSPTD 1133
               ***********98 PP

  == domain 3  score: -5.8 bits;  conditional E-value: 1
  DUF4683  318 LtpKksqkrKaKvkstkk..krikklkniesknikrtlsfrkrs 359 
               ++     k+++K ++t+k    +kk  + ++k++++++s rk++
   O60673 1186 IV----TKKRNKRNQTNKlvDDGKKKPRAKQKTNEKGTS-RKHT 1224
               22....333334444444111224444444444444444.2222 PP

  == domain 4  score: 1.6 bits;  conditional E-value: 0.01
  DUF4683  295 LAPLKdFWpkvpdsr.atkypvysLtpKksqkrKaKvkstkkkrikklkniesknikrtlsf.rkr 358 
               LA LK+  +k++++  + +  + +L +K+++++       + k+ k+ +++ s    rt  + +++
   O60673 1527 LAVLKELLQKRQQKAqNANTTQDPLSNKHQPNKNISGSLEHNKANKRTRSVTSPRKPRTPRStKQK 1592
               889999999988765588889999999999777666666666666666666666655555442222 PP

  == domain 5  score: -2.0 bits;  conditional E-value: 0.13
  DUF4683   93 kkknlaekkekeeaedkast.kekayiqknalnksisekeevlskdvkvakeaseekalidsansasvefedds..eesedalveikdisak 181 
               +k+++ ++++++  edk++t ++ ++i++ +l+ +i ek++  s++ +  ++ +++ +++    + s  + d    +++ed l+e + + + 
   O60673 1692 EKNEFLSHDNQKCDEDKHHTtDSASWIRSGTLSPEIFEKSTIDSNENRRHNQWKNSFHPL---TTRSNSIMDSFcvQQAEDCLSEKSRLNRS 1780
               45577888888777777766488899*******999999998888834333344444444...34555555555557777777777666543 PP



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