P42858 has 3142 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
0 1096.4 5.6 0 1095.2 5.6 1.6 1 P42858
Domain annotation for each sequence (and alignments):
>> P42858
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 1095.2 5.6 0 0 1 850 [. 756 1631 .. 756 1632 .. 0.97
Alignments for each domain:
== domain 1 score: 1095.2 bits; conditional E-value: 0
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqlli 97
y +h Dpq+rg++++l++++i ++ls+++ ++++w+ ++++ ++ ++++l +++ ll k+Lkdess+t++la++av+ C+ +L++S++++++Lql+i
P42858 756 YIDHGDPQVRGATAILCGTLICSILSRSRFHVGDWMGTIRTLTG-NTFSLADCIPLLRKTLKDESSVTCKLACTAVRNCVMSLCSSSYSELGLQLII 851
679***************************************99.9*************************************************** PP
Htt_N-HEAT 98 ellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.eed 179
++l l +s+ywlv++elle+la+++++lv+ ++t+ +lqervl++v+i+ll+dedprvr++aaa +++++pkLfyk+++ ++d
P42858 852 DVLTLRNSSYWLVRTELLETLAEIDFRLVSfleakaenlhrgahHYTGLLKLQERVLNNVVIHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQgQAD 948
************************************************************************************************* PP
Htt_N-HEAT 180 eitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsleypva 274
++a+A+++s+ +l+ l++ ++ sh s+i++++++y lL + t+ ++e++lSr+++++s++L++s+++al++gC+eal+ ls ++pv+
P42858 949 PVVAVARDQSSVYLKLLMHETQP-PSHFsvSTITRIYRGYNLLPS-----ITDVTMENNLSRVIAAVSHELITSTTRALTFGCCEALCLLSTAFPVC 1039
******************66644.33335799*************.....6888******************************************* PP
Htt_N-HEAT 275 lyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik...lsdsepsk........Wdals 360
++ +W+c v+ + +a+des++++++g++ ++l+LLss+++++dl+aH+d+LilagnLla++a ++++ +s++e W+al
P42858 1040 IWSLGWHCGVP------PLSASDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDALILAGNLLAASAPKSLRsswASEEEANPaatkqeevWPALG 1130
**********8......99******************************************************998777765446788999****** PP
Htt_N-HEAT 361 dtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqssparngi...............va 442
d+ lv+++eql++h+l+++ni+a+vlddv+pg+a+k+alpsl+++++lSp++r + kekep+e+ + + sp++ + ++
P42858 1131 DRALVPMVEQLFSHLLKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRR----KGKEKEPGEQASV-PLSPKKGSEasaasrqsdtsgpvtTS 1222
*****************************************************....9********9996.8888777778889999999***999* PP
Htt_N-HEAT 443 kkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvqqLLksL 539
k++slGsF+h+p+yl+l+++Lka+++nYkvtL+ +++++kf ++L+++L+v+sq+lelAtlq++gk++ee+L+ylk+++++ep++++ cvqqLLk+L
P42858 1223 KSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQQLLKTL 1319
************************************************************************************************* PP
Htt_N-HEAT 540 FgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvarklaavlk 627
FgtNlas+++ psk++ r++R ++s+ ++g+yh++f++P++++++al a++s ++vqae+e++ w+++l+k+s + +++l++v+k
P42858 1320 FGTNLASQFDglssnPSKSQGRAQR-LGSSSV---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAEQENDtsgWFDVLQKVSTQLKTNLTSVTK 1410
*************************.889999...9*******************..8888889********99*******************9999 PP
Htt_N-HEAT 628 gvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiFqFLvlLSy 724
+r+d+++i+n+IRlfE+lvik+LkqYt+t+ v+lqkqvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+rese++ip+iF+FLvlLSy
P42858 1411 -NRADKNAIHNHIRLFEPLVIKALKQYTTTTCVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSY 1506
.9*********************************************************************************************** PP
Htt_N-HEAT 725 eryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellilildscrveaneek 821
eryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q+evv+++LlrL++yh+v+e++il+l++c++e ne+k
P42858 1507 ERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQCHKE-NEDK 1602
********************************************************************************************.**** PP
Htt_N-HEAT 822 wkrasrqvadvvLpllaklkisldsthql 850
wkr+srq+ad++Lp+lak+++++ds+++l
P42858 1603 WKRLSRQIADIILPMLAKQQMHIDSHEAL 1631
***************************97 PP
Or compare P42858 to CDD or PaperBLAST