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Align Q08977 to PF10303 (DUF2408)

Q08977 has 551 amino acids

Query:       DUF2408  [M=130]
Accession:   PF10303.13
Description: Protein of unknown function (DUF2408)
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
    2.6e-67  211.6  26.8    1.2e-48  151.2   4.7    5.2  5  Q08977    


Domain annotation for each sequence (and alignments):
>> Q08977  
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   11.9   2.4   1.4e-05   1.4e-05       4     120 ..      13     130 ..      11     134 .. 0.77
   2 !    3.3   1.2    0.0064    0.0064      14      82 ..     119     199 ..     108     208 .. 0.49
   3 !  151.2   4.7   1.2e-48   1.2e-48       1     130 []     209     372 ..     209     372 .. 0.98
   4 !   31.9   0.1   9.5e-12   9.5e-12      39     119 ..     376     448 ..     373     450 .. 0.89
   5 !   40.2   0.0   2.5e-14   2.5e-14       4      97 ..     428     517 ..     425     525 .. 0.90

  Alignments for each domain:
  == domain 1  score: 11.9 bits;  conditional E-value: 1.4e-05
  DUF2408   4 lspelepiyekLvsirrsllslatrskke.sk...keelkelkkeLkeieskrde..egkfassetkevvekgqavlngLlddCldlvedlkakkeseekkl 99 
              +++e e+i++ L+++r sl++l  + ++  ++   +++ +++ ++++e+++ r++  e   +s  t  ++ +  + +++ ldd ++l++    +       l
   Q08977  13 VPKEEESILNYLLEVRSSLAKLKQNRTQYlNSkdvQTTYQHVLTKVRELDDIRKNshETPAKSAATLIHSTELHNRVDSVLDDVFQLLSLCFLT-----VGL 109
              78999*****************999988854455655666666666666666665322333334444477788999***********9998888.....579 PP

  DUF2408 100 dpklqpiYekLleikttLenL 120
              +++  ++Y +L+++ + Le+L
   Q08977 110 KNSAPATYASLSTVESLLEHL 130
              9999999*****999999998 PP

  == domain 2  score: 3.3 bits;  conditional E-value: 0.0064
  DUF2408  14 kLvsirrsllslatrskkeskkeelkelkkeLkeieskrde............egkfassetke..vvekgqavlngLlddCl 82 
               L ++   l  l+ ++ ++  +++l+ +k++L+ei +  ++            ++++ + ++++   + +++ +l+  l+ C 
   Q08977 119 SLSTVESLLEHLNESNVFT--HHDLSPIKERLEEISKIVEQknsspaydedgnDDRLREIDNERkkNKIEEDLLLRAKLKHCK 199
              5555555555555555555..67777777777777654444333444444443333333222111133333445555555555 PP

  == domain 3  score: 151.2 bits;  conditional E-value: 1.2e-48
  DUF2408   1 leelspelepiyekLvsirrsllslatrskke.sk..................................keelkelkkeLkeieskrdeegkfassetkevv 67 
              lee++p+l+ ++ekL+ irr+llsl++++kk+ sk                                  +e+l+ lk+eL+e+es+rd++gkf+s e+++v+
   Q08977 209 LEEIDPSLSTVMEKLFRIRRGLLSLVASAKKTmSKsdintnsllqeqndlqtnnesltddkhlvsqeyvHEKLSVLKNELSELESNRDDSGKFKSLESHQVA 310
              799****************************96669****************************************************************** PP

  DUF2408  68 ekgqavlngLlddCldlvedlkakkeseekkldpklqpiYekLleikttLenLllTrrWtLRE 130
              ekgq+vlngLlddC+dlv+dl+++k++   +ldp lqpiYe+L++ikttLenL++TrrWtLRE
   Q08977 311 EKGQSVLNGLLDDCHDLVNDLSHQKNGG-LTLDPYLQPIYEQLIDIKTTLENLMITRRWTLRE 372
              ************************9888.9********************************9 PP

  == domain 4  score: 31.9 bits;  conditional E-value: 9.5e-12
  DUF2408  39 kelkkeLkeieskrdeegkfassetkevvekgqavlngLlddCldlvedlkakkeseekkldpklqpiYekLleikttLen 119
               +++k+L+ei++kr + gkf +++   +++kgq++l  Ll++C  ++ +l ++    ++ ++++lqpi ++L++++  L +
   Q08977 376 FSYQKKLNEIDNKRIN-GKFPTKS---QDSKGQSILLYLLRRCYAIIYKLLES----SEPVSEALQPIHNQLSTVRRCLLE 448
              5799***********9.***5555...69***********************9....579***************998755 PP

  == domain 5  score: 40.2 bits;  conditional E-value: 2.5e-14
  DUF2408   4 lspelepiyekLvsirrsllslatrskkeskkeelkelkkeLkeieskrdeegkfassetkevvekgqavlngLlddCldlvedlkakkeseek 97 
              +s+ l+pi+++L ++rr ll+l      + ++ el  ++ +L  +++ r e g f +s++    ++gq +ln Ll++C+d++++lk + e++++
   Q08977 428 VSEALQPIHNQLSTVRRCLLELKRMGGVN-NERELYPYQMKLASLDNLRTE-GIFYDSDG--NIPEGQGILNALLAECFDILHELKVEAEEKAQ 517
              7899******************9999987.79******************9.***99999..899*********************99765433 PP



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