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Align Q54R54 to PF10154 (Fy-3)

Q54R54 has 746 amino acids

Query:       Fy-3  [M=498]
Accession:   PF10154.14
Description: Ferry endosomal RAB5 effector complex subunit 3
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence Description
    ------- ------ -----    ------- ------ -----   ---- --  -------- -----------
   2.7e-132  428.3  42.1     4e-125  404.6  19.0    3.0  2  Q54R54    


Domain annotation for each sequence (and alignments):
>> Q54R54  
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 !   25.6  18.0   3.3e-10   3.3e-10       6     212 ..      38     269 ..      33     272 .. 0.67
   2 !  404.6  19.0    4e-125    4e-125      18     497 ..     269     739 ..     266     740 .. 0.92

  Alignments for each domain:
  == domain 1  score: 25.6 bits;  conditional E-value: 3.3e-10
    Fy-3   6 rliaeeklPifvekdlkeelkkfveketlklydeka....................eqaleklredsvdvdsiakewekalkeelleyaekeea......... 79 
             + ++e ++P++ +  l +++++ +++ ++  +d+++                    +                   ++ ++++++   +    +         
  Q54R54  38 QFMNEYDIPCYFRISLLNTIENLIKQDKILTKDNDDieiilnikdgeiifdhnentN-------------------TNTNINNNCYISTSTIINqlsnqysek 121
             677888888888888888888888888888888887444444444433333332211...................222222222111111111233333334 PP

    Fy-3  80 .................saeekfa.tvyhklihspaletllqlektyakavkelvsernkelkklsekqteemekaiqelekeltdedvnelaakhfeeqqll 164
                              ++ee+++ + y    +s+  e +++ e+ +a++ + l+ +++  lk+l+ek+ +eme a     ++l +++v  ++a+++++ +  
  Q54R54 122 iqywnklagskeseeqkQQEERIStFLYLVDKNSDTRERIINQEELFATETSILLVKKQDDLKQLNEKHSREMEDAFR---NSLQPDQVELIVAQNMKQVDEF 221
             44444444445555555555554413455555889*****************************************99...89******************** PP

    Fy-3 165 ekkwnseleslkeeQkkeyrewvmklveelkspknksegseiknlsss 212
              + +++e++ lk++Qk e+ +++  l+  +k+ ++  e ++ + ++++
  Q54R54 222 DQYYDHEINILKQKQKFEFSKFLNDLYWLEKTKDDLDEIESFNSQQQQ 269
             *************************99877754444444443333333 PP

  == domain 2  score: 404.6 bits;  conditional E-value: 4e-125
    Fy-3  18 ekdlkeelkkfveketlklydekaeqaleklredsvdv.dsiakewekalkeelleyaekeeasaeekfatvyhklihs.paletllqlektyakavkelvse 118
             +++++++++++++k+++++++++++q++++++++s  + dsi+++++k ++            +a+++f++ ++k++++ p++++++++++ +++++++++++
  Q54R54 269 QQQQQQQQQQTPQKQQPPPPQQTPQQSQQSQPQSSGGIiDSIGQNLDKGVA------------RASSFFSFGFNKKNNQtPPINSPPSTPQLSSDDPNNVNNN 359
             5778899*****************************999***********9............789************************************9 PP

    Fy-3 119 rnkelkklse.kqteemekaiqel.......ekeltdedvnelaakhfeeqql............lekkwnseleslkeeQkkeyrewvmklveelkspknks 201
             +n++++++++ ++t+++++ i+++       ++++td++v+ +++ +++++++            +++++n+++++++++Q+k+                  s
  Q54R54 360 SNNNNNNNNNnNNTQSKPIGINNNnnnnssnNRQRTDSQVSPPNSLNSSSPNKppqpttplnnnnSNNNNNNNNNNNNSIQRKS------------------S 444
             998877766548999*******99999***99********************98887776444444444444444444444444..................7 PP

    Fy-3 202 egseiknlssslqdkesaeeelipedns.....leEsFTIhlGsQlKtmhNirllsadvldlcrleeegs...kksqrlqtalsLYSssLsglvLlvdnklns 296
             +gs+++nl+++lq+k+s+ + +ip+ ns     ++E+FTI +G+Q+K+++N++l+++++l+lcr+ ++ +   kks+r++++++LYS+sLs+++L++d++l++
  Q54R54 445 TGSSSTNLQPTLQRKQSGGAGNIPIINSgssssKFEDFTIGVGVQKKKIFNFKLIEESPLQLCRPITSLTgdyKKSKRVDYIKTLYSDSLSAVILIIDPSLQF 547
             89999************************************************************44444567****************************** PP

    Fy-3 297 ysgikkdFakiceestefHFesideQlekikeslreaeerrkekaegkeessakaasresknsktlsaGdfYiTrHSNLsevhvvFHlvvdd....slks.se 394
             +++++k+F+k+c++ste+HF+sid+Q++++k+sl+++eer+ke+            +++++n+++ls+Gdf+iT+HSNLs+v+vvFHlv+d+    +l + ++
  Q54R54 548 NTENEKKFIKYCNMSTELHFDSIDSQIHTFKQSLLKEEEREKEE------------NNNNNNNIKLSNGDFFITKHSNLSDVQVVFHLVIDSknrtPLGGdNQ 638
             *****************************************999............7888888*****************************999889999** PP

    Fy-3 395 insrhpvilGLRniLkvaasydittitiPllLth.elseemTiswclkRaelvfkcvkgfmiemaslggaelktvqfllPsgisee..vFktlaemlpqiFrv 494
             +++++++++GLRniL +a++y+i++itiP++Lt+ el+ ++T+s++l+R+++v++++++++++++++  +++ktvqf+lPs++++   +Fk   ++++q++++
  Q54R54 639 LSTTSDIAKGLRNILLTASKYGIGNITIPICLTEsELDLNVTNSNLLSRCVSVLSVTRASLTSLQEM--TSIKTVQFSLPSQLDSGntIFK---GPIAQKWKS 736
             *********************************99******************************99..9**************9867888...********9 PP

    Fy-3 495 anp 497
             a++
  Q54R54 737 AIN 739
             976 PP



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