Q59L86 has 872 amino acids
Query: DUF3246 [M=243]
Accession: PF11596.12
Description: Protein of unknown function (DUF3246)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.9e-95 305.0 105.3 2.4e-84 268.6 59.4 8.2 9 Q59L86
Domain annotation for each sequence (and alignments):
>> Q59L86
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -6.0 23.0 1 1 25 131 .. 89 226 .. 70 228 .. 0.47
2 ? -6.0 23.0 1 1 38 119 .. 168 252 .. 142 300 .. 0.49
3 ? 0.2 38.7 0.024 0.024 4 119 .. 197 384 .. 195 384 .. 0.65
4 ! 25.0 17.9 6.2e-10 6.2e-10 3 101 .. 318 402 .. 316 404 .. 0.72
5 ! 41.1 12.0 7.4e-15 7.4e-15 47 101 .. 402 454 .. 400 455 .. 0.93
6 ! 268.6 59.4 2.4e-84 2.4e-84 47 243 .] 454 645 .. 452 645 .. 0.98
7 ? -6.4 5.7 1 1 231 243 .] 683 695 .. 665 702 .. 0.67
8 ? -7.1 6.6 1 1 233 243 .] 735 745 .. 711 765 .. 0.68
9 ? -13.6 22.3 1 1 60 87 .. 795 822 .. 740 858 .. 0.51
Alignments for each domain:
== domain 1 score: -6.0 bits; conditional E-value: 1
DUF3246 25 ktgsstitlistlsnssvstkae.................ssitvvgtsstgsddddDdddetDceteietvPtgtttikptssgvitsiptas........ 101
++st+ s s+ss++t+++ s++ +++s + s++ + + +e + P ++ ++ ss++ t pta+
Q59L86 89 DSSNSTLVVPSS-SKSSTTTRSTaglldnllggsgatsseASSSEAPSSEAPSSEA-PSSEAPSSEAPSSEAPSSSSS-EALSSSSTTKRPTAAakgffgdl 187
544444332222.2233333333345666666664333322333332222222222.223444444433335644433.56666666666666666666666 PP
DUF3246 102 ........ddddetdc..etetitvepsivtvttgvtktt 131
+ d+ dc ete +t p+ + +t v++tt
Q59L86 188 fgtqssasE-TDDEDCveETESPTSAPASAPTTSKVATTT 226
666667744.444455224555666666666666666655 PP
== domain 2 score: -6.0 bits; conditional E-value: 1
DUF3246 38 snssvstkae......ssitvvgtsstgsdddd.DdddetDceteiet.vPtgtttikptssgvitsiptasddddetdcetetitveps 119
s ss++tk + gt+s++s+ dd D+ +et++ t + Pt + + ++++ ++p++ d + + + e+s
Q59L86 168 S-SSSTTKRPtaaakgFFGDLFGTQSSASETDDeDCVEETESPTSAPAsAPTTSKV----ATTTGGGLPNILSDLFPGKSSAPISSAESS 252
2.222222221211112234567777766654415788888887666556644444....444444556655554444444444444333 PP
== domain 3 score: 0.2 bits; conditional E-value: 0.024
DUF3246 4 DDEtdCdeetdiPt.......tetetttktgsstitlistlsnssvstkae................................................... 47
D++dC eet++Pt t++++ t+tg + + s+l ++s+ +
Q59L86 197 TDDEDCVEETESPTsapasapTTSKVATTTGGGLPNILSDLFPGKSSAPISsaessptvassttgfpnilsdlfpgkssvpsssaetsttvasntttsgggf 298
467799999999997777777666666666666655555554333322222455678888888899999999999999999999999999999999999999 PP
DUF3246 48 ........ssitvvgtsstgsddddDdddetDcet......eietvPtgtttikp.tssgvitsiptasddddetdcetetitveps 119
+ + v++ss + +dd++++d t++ t + +Pt ++t ++ ts +++ s t ddddet+cet+++t+ ps
Q59L86 299 pnilsdlfPGKSSVPSSS-AEEDDEECEDPTESVTsnssptGGISIPTFPITSQSkTSVSSVVSKSTSEDDDDETECETDIPTIIPS 384
998877765555555544.455566678888877644222222225555555332022233333345559*************9886 PP
== domain 4 score: 25.0 bits; conditional E-value: 6.2e-10
DUF3246 3 dDDEtdCdeetdiPttetetttktgsstitlistlsnssvstkaessitvvgtsstgsddddDdddetDceteiet.vPtgtttikptssgvitsiptas 101
++D+++C++ t++ t+++ +t + t++++s+ +s++ v ++st+ +dd ddet+cet+i+t +P g+++ pt+s+ +t ipt s
Q59L86 318 EEDDEECEDPTESVTSNSSPTGGISIPTFPITSQSK---------TSVSSVVSKSTS--EDD--DDETECETDIPTiIPSGSVL--PTTSVLPTIIPTGS 402
456668*99999977777766666666666555543.........444444444433..333..479************99999..***********976 PP
== domain 5 score: 41.1 bits; conditional E-value: 7.4e-15
DUF3246 47 essitvvgtsstgsddddDdddetDceteiet.vPtgtttikptssgvitsiptas 101
+ sit+++t+s++sddddD etDcet+i+t vPt+++ti pt+sg++t ipt s
Q59L86 402 SGSITILPTKSATSDDDDD---ETDCETDIPTiVPTESATIIPTGSGSVTIIPTGS 454
679***********99988...*******************************965 PP
== domain 6 score: 268.6 bits; conditional E-value: 2.4e-84
DUF3246 47 essitvvgtsstgsddddDdddetDceteiet.vPtgtttikptssgvitsiptas....ddddetdcetetitvepsivtvttgvtkttvvdsdGelvtkt 143
+ sitv++t+s++sddddD etDcet+i+t +Ptgt+tikpt+sg+it++pt+s ddddetdcete++t++p+ v++t++++sdG+ +t+t
Q59L86 454 SGSITVLPTKSATSDDDDD---ETDCETDIPTiIPTGTATIKPTGSGSITVLPTKStttdDDDDETDCETEIPTIHPT-------VSTTRTFTSDGVPTTQT 545
679***********99988...*********************************99**999****************.......999************** PP
DUF3246 144 vttklpvvtqtqtetevvtitytgaGqtfttyltqseeiCdEtvtvtvtttcptttvaqgGrvytttvtvitthtvyPedweddGyegedtgggsgggss 243
+ttklp++t+++tetevv+itytg+Gqtfttyltqs+eiCdEtvt+t+tttcp+ttva+gG++ytttvtvitthtvyP+dweddGyeged++ggs++gss
Q59L86 546 LTTKLPPTTNQHTETEVVSITYTGGGQTFTTYLTQSGEICDETVTLTITTTCPSTTVAPGGQIYTTTVTVITTHTVYPDDWEDDGYEGEDNAGGSASGSS 645
***************************************************************************************************8 PP
== domain 7 score: -6.4 bits; conditional E-value: 1
DUF3246 231 gedtgggsgggss 243
+t++gsg+gss
Q59L86 683 SGGTTSGSGSGSS 695
2344455555554 PP
== domain 8 score: -7.1 bits; conditional E-value: 1
DUF3246 233 dtgggsgggss 243
++g+gs++gss
Q59L86 735 GSGSGSSSGSS 745
33344444433 PP
== domain 9 score: -13.6 bits; conditional E-value: 1
DUF3246 60 sddddDdddetDceteietvPtgtttik 87
d+dd dd+++c+t+ +++t+
Q59L86 795 DDEDDSWDDDEECDTQAAKEVVNSVTVA 822
2222224444445543222111222211 PP
Or compare Q59L86 to CDD or PaperBLAST