XP_005093645.2 has 3024 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.4e-268 879.7 0.1 2.5e-268 878.9 0.1 1.4 1 XP_005093645.2
Domain annotation for each sequence (and alignments):
>> XP_005093645.2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 878.9 0.1 2.5e-268 2.5e-268 1 850 [. 608 1493 .. 608 1494 .. 0.92
Alignments for each domain:
== domain 1 score: 878.9 bits; conditional E-value: 2.5e-268
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlL 93
ya hsD ql+g ++l+l+ fi a l + + + +w+ + ++++ +l++l +++++ L des++ +r + a+++Cl++L+dS + ++L
XP_005093645.2 608 YAGHSDHQLKGQTALVLGSFIRAALLEGRADFSQWVMEHLP-SEQNVLSLEDLLRIIVNILGDESAVAVRAGLVALQMCLSHLLDSCHGRLGL 699
678*********************************88765.5569*********************************************** PP
Htt_N-HEAT 94 qlliellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfy 172
+l +ll +++++ywlvkvellel+a l++ ++ n+ ++ +lq++ ++++l++ll+ded+rvr aaa+a ++ipkLfy
XP_005093645.2 700 SILLDLLCIHNNPYWLVKVELLELMAGLNFKVISymesispditrgehNYLGKMCLQQHCIQEILLPLLGDEDARVRTAAANAFLRLIPKLFY 792
********************************************************************************************* PP
Htt_N-HEAT 173 ktrs.eedeitakAkelsekllscltellveleshdslisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleal 264
+++s ++d + a+A ++++ ll +++ + +l++ + +y + + + + a+es+lSr+v l++ Llvs s++++ gC++al
XP_005093645.2 793 ASDSpQQDPVLAVASDQTRYLLTPMMSPVLS-GQLPPLVQGLVGPYKH----DELAQVCPATESALSRVVQMLLHNLLVSNSRYITSGCCNAL 880
***********************99987744.3334677777777754....45567899********************************* PP
Htt_N-HEAT 265 lalsleypvalyekaWgckv........ksklkrd.............asvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagn 336
++ls+ey v+ y+ Wgc + + + +de + g+l++v+sL+ ss + lt+H+dlL lagn
XP_005093645.2 881 CRLSEEYLVTQYAASWGCGPakpivpkeS-----EerfgirrppsrslSASSMDELTAASGGGPLPIVMSLMLSSQAGLELTTHQDLLQLAGN 968
******************97676665430.....1345677777777755677888888888******************************* PP
Htt_N-HEAT 337 Llagaalrniklsdsepsk......Wdalsdtvlvrlaeqllrhvlrllnilaevlddvtpgqa.tkdalpslqalqvlSplkrlkeeekkek 422
L+agaa +n+k sd+ + + W a+sd++l ++ eql++h rlln +++ +++ +pg++ k+ lpsl + +lSp++r ++ek
XP_005093645.2 969 LVAGAAYKNLKNSDELDKTsgddvsWSAVSDRLLLPIIEQLFTHTARLLNACTHAIEETNPGPPqVKPSLPSLPNASTLSPVRRKMKGEK-DA 1060
***********77764444478888***********************************************************766644.33 PP
Htt_N-HEAT 423 epserlar...r..qssparngi....vakkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqed 506
+p+ ++ + + q +p + + +kk+ +G+F+++p+y++l+++L+++ysn+k +L+ ++dkf+++L+++L v+sqlle+Atlq+
XP_005093645.2 1061 SPQAPVGSpdpKtgQKTPGKDSKdsekDKKKDGIGAFYNIPQYMKLFDVLRGSYSNFKTSLDL-TSSDKFCTILRSALRVLSQLLEVATLQDV 1152
344333321123455565333335666678899******************************.99*************************** PP
Htt_N-HEAT 507 gkiaeevLmylkleiqsepkatvrcvqqLLksLFgtNlasnlspskqearllRealagslaam.lsgfyhkifqhPlarvsealrvanssssk 598
gk++ee+L+ylk+++ +ep+ tv cvqqLLk+LFgtNlas+++pskq a + +++ ++a ++g+yh++ ++P+a+++++l va++ +
XP_005093645.2 1153 GKVTEEMLGYLKVTMALEPTWTVLCVQQLLKALFGTNLASQWEPSKQSAAPILAEVSTRVTAGtSPGLYHHCLNRPYAQLAHCL-VAAACRAT 1244
********************************************9999988877888899888799******************.87777778 PP
Htt_N-HEAT 599 vqaeeeaewlgllkkkslkvarklaavlkg.vrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfi 690
+ a+e + l lk++ v+rkl+a+lk ++ d++ i +yIRlfE+lviksLkqYtvtss+elq+qvl LLaqL+qlrvnyclldsdq+fi
XP_005093645.2 1245 LPADEAHSSLLWLKQR---VDRKLPAILKPsSKVDKSVIGSYIRLFEPLVIKSLKQYTVTSSLELQCQVLALLAQLIQLRVNYCLLDSDQIFI 1334
8888888878888888...*********983566777788***************************************************** PP
Htt_N-HEAT 691 gfvLkqfeyiEeGqvresedlipkiFqFLvlLSyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakele 783
gfvLkqfeyiEeGq+r+se lip+iFqFLv+LSye+ hsk+ii +p+ii+ cdg+masg +++th+iPAl+P+v ++Fl+R++ k+e +k+le
XP_005093645.2 1335 GFVLKQFEYIEEGQIRNSELLIPHIFQFLVMLSYEKFHSKSIIDMPRIIHRCDGIMASGLQPTTHAIPALRPVVYELFLLRGTVKSEVGKDLE 1427
********************************************************************************************* PP
Htt_N-HEAT 784 aqrevvlakLlrLleyhevvellilildscrveaneekwkrasrqvadvvLpllaklkisldsthql 850
+qrevv+++LlrL++y + v++++l+l++c++e ee+wkr+srqv+dvvLp lak+ ++l s + l
XP_005093645.2 1428 TQREVVVSMLLRLVQYYQAVDMFVLVLQQCHRE-SEERWKRLSRQVMDVVLPALAKQTMNLCSQESL 1493
*********************************.9**************************998865 PP
Or compare XP_005093645.2 to CDD or PaperBLAST