XP_420822.3 has 3095 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
0 1067.4 5.1 0 1067.4 5.1 1.9 2 XP_420822.3
Domain annotation for each sequence (and alignments):
>> XP_420822.3
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 1067.4 5.1 0 0 1 850 [. 710 1585 .. 710 1586 .. 0.97
2 ? -2.0 0.0 0.046 0.046 350 416 .. 2241 2308 .. 2227 2321 .. 0.81
Alignments for each domain:
== domain 1 score: 1067.4 bits; conditional E-value: 0
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqll 96
y +h Dpq+rg++++l+++ i+++l +++ +e+wl +++s ++ + ++l +++ ll+k+Lkdess+t++la++av++C+ +L++S++++++Lql+
XP_420822.3 710 YIDHGDPQIRGATAILCGTIINSILLKSRFDVEKWLVNVRSSTG-NLFSLVDCIPLLQKTLKDESSVTCKLACTAVRHCIMSLCSSSYSELGLQLI 804
679**************************************999.9************************************************** PP
Htt_N-HEAT 97 iellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.e 177
+ll lk+s+ywlv++elle+la+++++lv+ ++t+ ++qervl++v+i ll+dedprvr++aaa + +++pkLfy++++ +
XP_420822.3 805 VDLLTLKNSSYWLVRTELLETLAEVDFRLVSflegktdslhrgvhHYTGLLKIQERVLNDVVICLLGDEDPRVRHVAAASLMRLVPKLFYNCDQgQ 900
************************************************************************************************ PP
Htt_N-HEAT 178 edeitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsley 271
+d ++a+A+++s +l+ l++ ++ sh s+i++ +++y +L++ t+ ++e++lSr+v+++s+ L++s+++ l++gC+eal+ ls ++
XP_420822.3 901 ADPVVAVARDQSGVYLKLLMHETQP-PSHFavSTITRTYRGYNMLQN-----PTDVTMENNLSRVVAAISHALTISTTRSLTFGCCEALCLLSTTF 990
********************65533.33446789999*********9.....8899**************************************** PP
Htt_N-HEAT 272 pvalyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik..lsdsepsk.........W 356
pv++++ +W+c v+ + +d+ ++ +++g++ +vlsLLss ++++dl+aH+d+Lil gnLla++a + +k s +e+s+ W
XP_420822.3 991 PVCTWTVGWHCGVS------QPSPSDDAQKGCTIGMAGMVLSLLSSTWFPLDLSAHQDALILTGNLLAASAPKCLKnpWSAEEDSNqvaakqeepW 1080
************96......346689**************************************************9955555555588999999* PP
Htt_N-HEAT 357 dalsdtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqssparngi............ 440
+al d++lv l+eql++h+l+++ni+a+v+ddv+pg+a k+alpsl+++++lSp++r + ke+ep e+++ ++sp++ g+
XP_420822.3 1081 PALADRTLVTLVEQLFSHLLKVINICAHVMDDVAPGPAVKAALPSLTNPPSLSPIRR----KGKEREPVEQTSV-PMSPKKGGEtspatrqtdasg 1171
*********************************************************....9*********997.9***999999*********** PP
Htt_N-HEAT 441 ...vakkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvq 533
++k++s+GsF+h+p+yl+ly++Lka+++nYkvtL+ +++++kf +L+++L+v+sq+lelAtlq++gk++ee+L+ylk+++++ep++++ cvq
XP_420822.3 1172 papTSKSSSVGSFYHLPSYLKLYDVLKATHANYKVTLDLQNSNEKFGCFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFNREPTMATVCVQ 1267
************************************************************************************************ PP
Htt_N-HEAT 534 qLLksLFgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvar 620
qLLk+LFgtNlas+++ sk + +++R +++l ++g+yh++f++P++++++al a++s ++vqae+e++ w+++l+k+s + ++
XP_420822.3 1268 QLLKTLFGTNLASQYDglssnTSKAQGKAQR-LGSSNL---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAEQEHDasgWFDVLQKVSTQLKT 1357
****************888887788888888.667778...9*******************..8988889************************** PP
Htt_N-HEAT 621 klaavlkgvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiF 716
++++ k r+d+++i+n+IRlfE+lvik+LkqYt+t+sv+lq+qvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+rese++ip+iF
XP_420822.3 1358 NITSAAK-HRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQRQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIF 1452
***8888.9*************************************************************************************** PP
Htt_N-HEAT 717 qFLvlLSyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellililds 812
+FLvlLSyeryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q+evv+++LlrL++yh+v+e++il+l++
XP_420822.3 1453 FFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQ 1548
************************************************************************************************ PP
Htt_N-HEAT 813 crveaneekwkrasrqvadvvLpllaklkisldsthql 850
c++e ne+kwkr+srq+ad++Lp+lak+++++ds+++l
XP_420822.3 1549 CHKE-NEDKWKRLSRQIADIILPMLAKQQMHIDSHDAL 1585
****.*******************************97 PP
== domain 2 score: -2.0 bits; conditional E-value: 0.046
Htt_N-HEAT 350 dsepskWdalsdtvlvrlaeqllrhvlrllnil.aevlddvtpgqatkdalpslqalqvlSplkrlke 416
++ps W+ l + v +a l+ + ++ + +e+ ++ + + +k+a + l++ +v S ++++k+
XP_420822.3 2241 LQQPSLWNLLASAANVTYACSLINCIKFIIEAVaVEPGNQLLSPERKKNASKGLSEDEVDSNMHKMKH 2308
467888******************9998887651566777766666******************9864 PP
Or compare XP_420822.3 to CDD or PaperBLAST