XP_536221.2 has 3130 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
0 1092.5 3.0 0 1091.7 3.0 1.4 1 XP_536221.2
Domain annotation for each sequence (and alignments):
>> XP_536221.2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ! 1091.7 3.0 0 0 1 850 [. 746 1621 .. 746 1622 .. 0.97
Alignments for each domain:
== domain 1 score: 1091.7 bits; conditional E-value: 0
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqll 96
y +h Dpq+rg++++l++++i ++ls+++ ++++w+ ++++ ++ ++++l ++v ll+k+Lkdess+t++la++av++C+ +L++S++++++Lql+
XP_536221.2 746 YIDHGDPQVRGATAVLCGTLISSILSRSRFQVGDWMGTVRTLTG-STFSLADCVPLLQKTLKDESSVTCKLACTAVRHCVMSLCSSSYSELGLQLI 840
679****************************************9.99************************************************* PP
Htt_N-HEAT 97 iellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.e 177
+++l lk s+ywlv++elle+la+++++lv+ ++t+ +lqervl++v+i+ll+dedprvr++aaaa+ +++pkLfyk+++ +
XP_536221.2 841 TNVLTLKDSSYWLVRTELLETLAEIDFRLVSfletkaenlhrgthHYTGLLKLQERVLHDVVIYLLGDEDPRVRHVAAAALMRLVPKLFYKCDQgQ 936
************************************************************************************************ PP
Htt_N-HEAT 178 edeitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsley 271
+d ++a+A+++s+ +l+ l++ + sh s+i++++++y lL + t+ ++e++lSr+++++s +L++s+++al++gC+eal+ ls ++
XP_536221.2 937 ADPVVAVARDQSSVYLKLLMHEAQP-PSHFsvSTITRIYRGYNLLPS-----MTDVTVENNLSRVIAAVSRELVTSTTRALTFGCCEALCLLSTAF 1026
********************76644.33335699*************.....7888**************************************** PP
Htt_N-HEAT 272 pvalyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik...lsdsepsk........W 356
pv+ ++ +W+c v+ + + +des++++++g++ ++l+LLss+++++dl+aH+d+L+lagnLla++a ++++ +s++e W
XP_536221.2 1027 PVCIWSLGWHCGVP------PLSTSDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDALVLAGNLLAASAPKSLRsswTSEEEANPatskqeevW 1116
*************8......8999****************************************************999777775445688999** PP
Htt_N-HEAT 357 dalsdtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqssparngi............ 440
+al d++lv+++eql++h+l+++ni+a+vlddv+pg+a+k+alpsl+++++lSp++r + kekep+e+ + + sp++ +
XP_536221.2 1117 PALGDRTLVPMVEQLFSHLLKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRR----KGKEKEPGEPASV-PLSPKKGSEaspasrqsdapg 1207
*********************************************************....99*******8886.778866666788888888*** PP
Htt_N-HEAT 441 ...vakkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvq 533
++k++slGsF+h+p+yl+l+++Lka+++nYkvtL+ +++++kf ++L+++L+v+sq+lelAtlq++gk++ee+L+ylk+++++ep +++ cvq
XP_536221.2 1208 pvtANKSSSLGSFCHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPVMATVCVQ 1303
*9999******************************************************************************************* PP
Htt_N-HEAT 534 qLLksLFgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvar 620
qLLk+LFgtNlas+++ psk++ r++R ++s+ ++g+yh++f++P++++++al a++s ++vq+e+++ w+++l+k+s + ++
XP_536221.2 1304 QLLKTLFGTNLASQFDglssnPSKSQGRAQR-LGSSSV---RPGLYHYCFMAPYTHFTQAL--ADASLrTMVQTEQDHGtsgWFDVLQKVSTQLKT 1393
*******************************.889999...9*******************..888888999*999998999************** PP
Htt_N-HEAT 621 klaavlkgvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiF 716
+l++ +k +r+d+++i+n+IRlfE+lvik+LkqYt+t+sv+lq+qvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+rese++ip+iF
XP_536221.2 1394 NLTSATK-NRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQRQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIF 1488
***9888.9*************************************************************************************** PP
Htt_N-HEAT 717 qFLvlLSyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellililds 812
+FLvlLSyeryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q+evv+++LlrL++yh+v+e++il+l++
XP_536221.2 1489 FFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQ 1584
************************************************************************************************ PP
Htt_N-HEAT 813 crveaneekwkrasrqvadvvLpllaklkisldsthql 850
c++e ne+kwkr+srq+adv+Lp+lak+++++ds+++l
XP_536221.2 1585 CHKE-NEDKWKRLSRQIADVILPMLAKQQMHIDSHEAL 1621
****.*******************************97 PP
Or compare XP_536221.2 to CDD or PaperBLAST