XP_643500.1 has 2516 amino acids
Query: DUF4457 [M=323]
Accession: PF14652.10
Description: Domain of unknown function (DUF4457)
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
3e-151 489.2 32.5 1.6e-120 388.2 6.2 11.2 11 XP_643500.1
Domain annotation for each sequence (and alignments):
>> XP_643500.1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -6.1 4.6 1 1 155 176 .. 22 43 .. 10 76 .. 0.44
2 ? -20.4 29.8 1 1 137 182 .. 210 255 .. 194 352 .. 0.63
3 ? -21.9 24.3 1 1 148 260 .. 412 520 .. 393 550 .. 0.49
4 ? -19.8 20.1 1 1 263 263 .. 708 708 .. 648 812 .. 0.62
5 ? -8.2 5.8 1 1 238 268 .. 872 902 .. 855 918 .. 0.41
6 ? -17.1 20.0 1 1 157 204 .. 970 1017 .. 954 1090 .. 0.49
7 ? -18.5 19.1 1 1 222 238 .. 1111 1127 .. 1053 1190 .. 0.55
8 ? -7.0 5.0 1 1 158 184 .. 1452 1477 .. 1436 1486 .. 0.39
9 ! 53.2 2.6 1.4e-18 1.4e-18 141 260 .. 1511 1636 .. 1506 1639 .. 0.72
10 ! 80.3 7.9 8.1e-27 8.1e-27 47 160 .. 1638 1769 .. 1634 1862 .. 0.77
11 ! 388.2 6.2 1.6e-120 1.6e-120 2 322 .. 2013 2389 .. 2012 2390 .. 0.92
Alignments for each domain:
== domain 1 score: -6.1 bits; conditional E-value: 1
DUF4457 155 kleeeeksvesklkskskkvee 176
++++++++++++++ +++++
XP_643500.1 22 NNNNNNNNNNNNNNNNNNNNNN 43
3333211111111111111111 PP
== domain 2 score: -20.4 bits; conditional E-value: 1
DUF4457 137 pGnsafdfaqtillqeedkleeeeksvesklkskskkveevsqdye 182
+ ++ ++q+ + q+++++++++++++++++++++++++ +q+++
XP_643500.1 210 SQQHQHQHQQQQQQQHQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQ 255
4444444444433333333333211111111111111111111111 PP
== domain 3 score: -21.9 bits; conditional E-value: 1
DUF4457 148 illqeedkleeeeksvesklkskskkveevsqdyeapllpsgfvlklqllstwGDkyyiGLnglelydekgekikltesniaalpesvnvldevsgdv 245
i l++++ ++++++++++++ + +++ +++ ++ p+ f+++l l ++ n + ++++++i+ +++n + + ++ n ++ +++
XP_643500.1 412 INLSQMNNINQNNNNNSNNN----NSNSNSNTNNGNNTQPKKFTFSLPLSMLNNNNNVNNGNNSNNSNNNNNSISGNNNNNNNNNNNNNNNNNNNNNN 505
34444444444222222222....22333333444445566666666655444444443344445566677777666666555554444333333322 PP
DUF4457 246 rtpdklidgvnntld 260
++ ++ ++ nn+++
XP_643500.1 506 NNNNNNNNNNNNNNN 520
222222222222222 PP
== domain 4 score: -19.8 bits; conditional E-value: 1
DUF4457 263 h 263
+
XP_643500.1 708 N 708
0 PP
== domain 5 score: -8.2 bits; conditional E-value: 1
DUF4457 238 ldevsgdvrtpdklidgvnntlddrhmwlap 268
+++ ++ ++ ++ i++ nn++++++ ++
XP_643500.1 872 INNNNNINNINNNNINNNNNNNNNNNNINNQ 902
3333332233333344333333333333333 PP
== domain 6 score: -17.1 bits; conditional E-value: 1
DUF4457 157 eeeeksvesklkskskkveevsqdyeapllpsgfvlklqllstwGDky 204
++++ +++++++++++ +++ +q+++ p + + + l++ G +y
XP_643500.1 970 QQQQPQIQQQQQQQQQPQQQQQQQQQQPQIQQQQQQPNVNLNNNGKPY 1017
222333344444444444444444444444443333333344445444 PP
== domain 7 score: -18.5 bits; conditional E-value: 1
DUF4457 222 kltesniaalpesvnvl 238
+ +++n + + +s+n+
XP_643500.1 1111 SYNNNNTTNNNSSININ 1127
22233333333333333 PP
== domain 8 score: -7.0 bits; conditional E-value: 1
DUF4457 158 eeeksvesklkskskkveevsqdyeap 184
+ +++++++++++ ++++++s ++e++
XP_643500.1 1452 N-NNNNNNNNNNNNNNNNSHSINQETD 1477
1.2222222222223333333333333 PP
== domain 9 score: 53.2 bits; conditional E-value: 1.4e-18
DUF4457 141 afdfaqtillqeedkleeeeksvesklkskskkveevsqdyeap...llpsgfvlklqllstwGDkyyiGLnglelydekgekiklt..esniaal 231
+fd ++ i +e+ kl++++++++++++++ ++ +q+ ap l p+g v+ ++++stwGD++y+GL g++++d++g+ +kl+ +s+i+a+
XP_643500.1 1511 TFDLQHVINSTEKLKLTSNNNNNSNNNNKQPSTPIIETQSFGAPlltLNPTGRVITINIYSTWGDQHYVGLSGIDIFDSNGSYVKLKdpKSQIKAF 1606
68988888886666666544444444444333333444555554111569*********************************988744799**** PP
DUF4457 232 pesvnvldevsg.dvrtpdklidgvnntld 260
p+++n +++ ++ + ++ ++ ++g++n +
XP_643500.1 1607 PSDLNDINNNNNnNNNNNNNNVNGHSNRNH 1636
*****9966655266677788888877665 PP
== domain 10 score: 80.3 bits; conditional E-value: 8.1e-27
DUF4457 47 eysgdkrtldklidgtnvttddehmwlipfsegkehvltidfkkeksisglriwNYnksledtfrgakkvsvsldgkslspkegfllrkapGnsa. 141
++s+d rt+dk++dg+ t+dd+h+wl pf++g+ +++ti+++++ ++s +riwNYnks ++rgak +++++d++ + + ++k pG +
XP_643500.1 1638 QHSNDPRTIDKIMDGHPRTCDDNHLWLAPFTAGQVNTITITLDSKITLSLIRIWNYNKSRIHSSRGAKDIEIKIDNSYVIFRG--SIKKSPGILQg 1731
699*************************************************************************9998877..79*****9876 PP
DUF4457 142 .fdfaqtillqeedkleee..................e 160
+ + i++++++ + ++ +
XP_643500.1 1732 cEQYCEYIVFTNKEEIFNRieendpfspsfihdennsN 1769
4679999***9999988876666677666665433220 PP
== domain 11 score: 388.2 bits; conditional E-value: 1.6e-120
DUF4457 2 nllstWgDsyylGLtglevldeegkaiplqlenikakprdlndlpeysgdkrtldklidgtnvttddehmwlipfsegkehvltidfkkeksisgl 97
+lstWgD++y+GLt+++v+d+e+k+ip+q++ni+a+p+d+nd+p++sgd+rtldklidg+nvtt+d+hmwlipfs++kehvltid+++ sis++
XP_643500.1 2013 LFLSTWGDRFYMGLTSIMVFDNEYKQIPIQASNITAQPKDINDVPGHSGDYRTLDKLIDGHNVTTNDKHMWLIPFSPSKEHVLTIDLGNVFSISCI 2108
699********************************************************************************************* PP
DUF4457 98 riwNYnksledtfrgakkvsvsldgkslspke.........................gfllrkapGnsafdfaqtillqeedkleee.eksveskl 167
riwNYnksl+d++rgakkv+++ldg+slsp+ gf++rkapGns+fdf+qti++ ++dkl+++ ++++++++
XP_643500.1 2109 RIWNYNKSLDDASRGAKKVNIFLDGQSLSPPPaaaassssssssplnniqnnnqnnyGFIFRKAPGNSTFDFGQTISFFNWDKLNNNnNNNINNNN 2204
******************************999***********************99**************************998566677777 PP
DUF4457 168 kskskkveevsqdyeapllpsgfvlklqllstwGDkyyiGLnglelydekgekikltesniaal..pesvnvl.devsg.....dvrtpdklidgv 255
+ s++++ ++q++ +++ +sgfvlkl+++s++GD++++GL+++e+yd++++ ik ++s++ ++ ++s++++ + + +p +++
XP_643500.1 2205 NPPSSCSSGTDQNKISQY-SSGFVLKLVIISNYGDRNFVGLHAIEIYDQNDTIIKPNKSSVLSNdvKNSYKLIgN-NLSfqeseGFLIPYFSVSFG 2298
778888888888877766.9*****************************************999889****9962.32223344899999999999 PP
DUF4457 256 nntldd.....rhmwlap...................ilpglvnkiyvifdePvtvsmiklWNYsktpsrgvkeleilvDDlliykGilkk 322
n+++++ +h+++++ + +++ n iy++fd+P+tv++ik+WNY+k+ s+++ke++i++DDlli++G+l+k
XP_643500.1 2299 NSNNNNgmsplYHQQQQQqyqlggnsvsynsrgleipSFSKESNVIYFYFDSPITVGKIKIWNYFKNISQAIKEYSIYLDDLLINQGTLQK 2389
96655546666555555589**************88888888999********************************************98 PP
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