XP_001364862.1 has 3135 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
0 1078.7 3.8 0 1078.7 3.8 2.1 2 XP_001364862.1
Domain annotation for each sequence (and alignments):
>> XP_001364862.1
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -1.2 0.9 0.027 0.027 61 277 .. 121 380 .. 83 408 .. 0.61
2 ! 1078.7 3.8 0 0 1 850 [. 749 1624 .. 749 1625 .. 0.97
Alignments for each domain:
== domain 1 score: -1.2 bits; conditional E-value: 0.027
Htt_N-HEAT 61 Lkde.ssgtlrlaisavesClrn....LadSkeflqlLqllie...................llalktsaywlvkvell..ellaklkyvlve.. 127
L+++ ++r+ + Cl++ L++S+ + L+l e l lv+ + + +l++ l+ +
XP_001364862.1 121 LCSDdAESDVRM---VADECLNKvikaLMESNLPRLQLELYKEikkngasrslraalwrfaeL-------AHLVRPQKCrpYLVNLLPCLTRIsk 205
443325567777...445666666666888888888888887777778777776643333330.......2345544443344444444443311 PP
Htt_N-HEAT 128 ......................nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrseedeitakAkelsekllscltell 200
n +++ +vl ++ ia l+ p +r++aa v++ + ++ + l + ll+ l +
XP_001364862.1 206 rteesvqetlaaaipkimasfgNFANDNEI--KVLLKAFIANLKSSSPTIRRTAAGSAVSICQ--------HSRRTQYFYTWLLNVLLGLLVPVE 290
111244444444444444444333333333..3335667777777777777777777777644........223445666667777777777555 PP
Htt_N-HEAT 201 veleshd...............slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsas..kalllgCleallalsleypvalye 277
e h+ +l ++ +k +s L++ +v+r++ ++ s +++ + L+ + +++++g le+l +l ++ pv l++
XP_001364862.1 291 EE---HStlfilgvlltlryliPLLQQQVKDMS-LKGSFGVTRKETEISPSTDQLIQVYELTLHYTQHqdHNVVTGALELLQQLFKTPPVELLQ 380
33...3335566666666666666677777666.566688888888888888888888888887766555778899999999998888887765 PP
== domain 2 score: 1078.7 bits; conditional E-value: 0
Htt_N-HEAT 1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlL 93
y +h Dpq+rg++++l+++ i+++l +++ ++e+wl +++ ++ ++++l +++ ll+k Lkdess+t++la++av++C+ +L++S ++++L
XP_001364862.1 749 YIDHGDPQIRGATAILCGTIIYSILNKSRFSVENWLTAVRNSTG-NTFSLVDCIPLLQKSLKDESSVTCKLACTAVRHCVMSLCSSCFSELGL 840
679*************************************9999.9*********************************************** PP
Htt_N-HEAT 94 qlliellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfy 172
ql+i++l l +s+ywlv++ell++la+++++l++ ++t+ +lq+rvl++v+i+ll+dedprvr++aa+ +++++pkLfy
XP_001364862.1 841 QLIIDVLTLRNSSYWLVRTELLDTLAEIDFRLISfleakadhlhkgshHYTGLLKLQDRVLNNVVIYLLGDEDPRVRHVAASSLIRLVPKLFY 933
********************************************************************************************* PP
Htt_N-HEAT 173 ktrs.eedeitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCle 262
++++ + d ++a+A+++s+ +l+ l++ ++ sh s+i++ +++y lL + t+ ++e++lSr+++++s+ L++s+++al++gC+e
XP_001364862.1 934 NCDQgQTDPVVAVARDQSNVYLKLLMHETQP-PSHFsvSTITRTYRGYNLLPS-----ITDVTMENNLSRVIAAVSHALTTSTTRALTFGCCE 1020
**************************66644.33335699*************.....6888******************************* PP
Htt_N-HEAT 263 allalsleypvalyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik...lsdse 352
al+ ls ++pv+ ++ +W+c v+ + + +des++++++g++ vl+LLss+++++dl+aH+d++ilagnLla++a +++k ++++e
XP_001364862.1 1021 ALCLLSTAFPVCIWSLGWHCGVP------LLSPSDESRKSCTVGMATTVLTLLSSAWFPLDLSAHQDAIILAGNLLAASAPKSLKnpwTTEDE 1107
**********************8......8999****************************************************99844444 PP
Htt_N-HEAT 353 psk........WdalsdtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqsspar 437
W+al d+vlv+++eql++h+l+ +ni+a+vlddvtpg+a+k+alpsl+++++lSp++r + kekep+e+ + + sp++
XP_001364862.1 1108 ANPgamkqeepWPALGDRVLVQMVEQLFSHLLKAINICAHVLDDVTPGPAIKAALPSLTNPPSLSPIRR----KGKEKEPGEQASV-PLSPKK 1195
332458999************************************************************....99*******9986.888877 PP
Htt_N-HEAT 438 ngi...............vakkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLm 515
++ ++k+++lGsF+h+p+yl+ly++Lka+++nYkvtL+ +++++kf ++L+++L+v+sq+lelAtlq++gk++ee+L+
XP_001364862.1 1196 GNEaspasrssdpsgpaiTSKSSTLGSFYHLPSYLKLYDVLKATHANYKVTLDLQNSSEKFGGFLRAALDVLSQILELATLQDIGKCVEEILG 1288
77788888888999999999************************************************************************* PP
Htt_N-HEAT 516 ylkleiqsepkatvrcvqqLLksLFgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqae 602
ylk+++++ep++++ cvqqLLk+LFgtNlas+++ psk++ +++R ++sl ++g+yh++f++P++++++al a++s ++vqa+
XP_001364862.1 1289 YLKSCFNREPTMATVCVQQLLKTLFGTNLASQYDglsskPSKSQGKAQR-LGSSSL---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAD 1375
*************************************************.889999...9*******************..8988889***** PP
Htt_N-HEAT 603 eeae...wlgllkkkslkvarklaavlkgvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigf 692
+e++ w+++l+k+s + +++l++v+k r+d+++i+n+IRlfE+lvik+LkqYt+t+sv+lq+qvl+LLaqLvqlrvnyclldsdqvfigf
XP_001364862.1 1376 QEHDtsgWFDVLQKVSTQLKTNLTSVTK-HRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQRQVLDLLAQLVQLRVNYCLLDSDQVFIGF 1467
************************9999.9*************************************************************** PP
Htt_N-HEAT 693 vLkqfeyiEeGqvresedlipkiFqFLvlLSyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaq 785
vLkqfeyiE+Gq+rese++ip+iF+FLvlLSyeryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q
XP_001364862.1 1468 VLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQ 1560
********************************************************************************************* PP
Htt_N-HEAT 786 revvlakLlrLleyhevvellilildscrveaneekwkrasrqvadvvLpllaklkisldsthql 850
+ev +++LlrL++yh+v+e++il+l++c++e ne+kwkr+srq+ad++Lp+lak+++++ds+++l
XP_001364862.1 1561 KEVAVSMLLRLIQYHQVLEMFILVLQQCHKE-NEDKWKRLSRQIADIILPMLAKQQMHIDSHEAL 1624
*******************************.*******************************97 PP
Or compare XP_001364862.1 to CDD or PaperBLAST