NP_189404.2 has 1841 amino acids
Query: DUF3730 [M=227]
Accession: PF12530.12
Description: Focadhesin/RST1, DUF3730
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
1.2e-122 393.7 15.6 3.5e-72 228.7 3.1 3.9 6 NP_189404.2
Domain annotation for each sequence (and alignments):
>> NP_189404.2
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.9 0.5 0.46 0.46 122 157 .. 47 79 .. 46 80 .. 0.70
2 ! 180.7 4.7 1.6e-57 1.6e-57 1 225 [. 82 353 .. 82 356 .. 0.97
3 ? -3.7 0.0 0.39 0.39 51 71 .. 408 428 .. 399 447 .. 0.78
4 ! 228.7 3.1 3.5e-72 3.5e-72 10 227 .] 532 750 .. 523 750 .. 0.94
5 ? -3.0 0.1 0.25 0.25 127 180 .. 875 933 .. 870 941 .. 0.59
6 ? -1.8 0.1 0.11 0.11 13 62 .. 1506 1561 .. 1495 1593 .. 0.70
Alignments for each domain:
== domain 1 score: -3.9 bits; conditional E-value: 0.46
DUF3730 122 alsavLvecesespevqalglealeeLceaevvdls 157
a+s +L +ses +v +++ l L + v+dls
NP_189404.2 47 AISFCL---TSESITVVDQSVHELCRLVSDSVLDLS 79
677788...777777777666666666666799987 PP
== domain 2 score: 180.7 bits; conditional E-value: 1.6e-57
DUF3730 1 LllLlyklekesnpelvlkllkaLpsLashk.........vcvPlvlqfvqaLssrk..asellqavalrLlaklwkkedrvypfLqkllaf...... 81
Ll+L+++le++ +++lv++++k+L++L++++ ++++++++fv++ ssr+ ++ell++v+l+++++ + ++++v++fL+++l+f
NP_189404.2 82 LLELQSALEGC-DSKLVSLFVKGLGFLIRIGyernngnwkFNSTENHPFVRIQSSRVetQTELLHQVSLFVMHNRRLGMVGVCEFLEPFLNFtilrip 178
799********.************************************************************************************** PP
DUF3730 82 .skssesafarslievllslAas...........irdickerPdqhged....LvdalsavL...vecesespevqalglealeeLcea......... 151
s+ss+s+far+li++++sl++s +++++k+ P ++ e Lvda+++v+ v++ e++ev++lg+++++ ++
NP_189404.2 179 lSDSSSSLFARELISSMASLCCSsrhealpifrlLMRCLKYIPGNNLEVivkiLVDAYTVVVrdlVGTGLEVTEVHLLGVQLVDGVLFLcasphvqtt 276
*********************************************9999***********************************88777778****** PP
DUF3730 152 ..e.vvdlssawkviqkklsldkrPevlksllsLlallaqleveheqyeelklevllllWklessqddarvasaafe 225
e v++ ++++ ++qk+l+l ++++++ ++lsL+++la+++veheq++ lk ++ll+Wk+es++ + ++a+ ++
NP_189404.2 277 eqEsVIESLKHLLAVQKDLGLAYSHDLSLVVLSLVFMLAKSTVEHEQLCILKFLLFLLKWKTESENLSVKDAAGSSV 353
**67**************************************************************98877766554 PP
== domain 3 score: -3.7 bits; conditional E-value: 0.39
DUF3730 51 ellqavalrLlaklwkkedrv 71
+++ +v r +++lw ++d +
NP_189404.2 408 SRVGSVVFRFMQQLWHQNDYT 428
567889999999999998854 PP
== domain 4 score: 228.7 bits; conditional E-value: 3.5e-72
DUF3730 10 kes....npelvlkllkaLpsLashkvcvPlvlqfvqaLssrkasellqavalrLlaklwkkedrvypfLqkllafskssesafarslievllslAas 103
++ +++l++kll +LpsLa+++v++Plv+q++ ++++++a+ ll+a+a+rLl+++w ++dr++++Lq++l ++ +++ s++++++s+Aas
NP_189404.2 532 LSRtnvpCQSLLSKLLGLLPSLAAQQVMIPLVVQTITPMLRKDAKGLLYATAIRLLCQTWVVNDRAFSSLQEVLR---PQGFIEYISERHICISMAAS 626
333345599******************************************************************...******************** PP
DUF3730 104 irdickerPdqhgedLvdalsavLvecesespevqalglealeeLceaevvdlssawkviqkklsldk.rPevlksllsLlallaqleveheqyeelk 200
i+d+ck++Pd+ g+dL+++++a++ es+++ v+alg+++l++Lcea+v+d+++aw+vi+k+ ++ k +P+++ s+++Ll+++a +++e+y+e +
NP_189404.2 627 IHDVCKRHPDR-GVDLILSVQACI---ESQNCPVRALGFQSLSHLCEADVIDFYTAWDVIKKHAQHIKlDPLLAYSVCHLLKWGA---MDAEAYPEDA 717
***********.************...**********************************************************...********** PP
DUF3730 201 levllllWklessqdda......rvasaafeaL 227
++vl++lW+++ss++++ +++++a++aL
NP_189404.2 718 ENVLNILWEIGSSMQKPhdsqwtKARVSAIVAL 750
***************888888888888888876 PP
== domain 5 score: -3.0 bits; conditional E-value: 0.25
DUF3730 127 Lvecesesp.evqalglealeeLcea....evvdlssawkviqkklsldkrPevlksll 180
+ +++ + + + ++++l++l++ ++ ++++ + k ++ + +++ ++ksl+
NP_189404.2 875 VKSLQLSRNiSLALISLQSLKAFMRRwmraNILSIDATTKELSSDKTSKATNNIMKSLV 933
44445555557788888888888777555456666555555555555555555555555 PP
== domain 6 score: -1.8 bits; conditional E-value: 0.11
DUF3730 13 npelvlkllkaLpsLashk......vcvPlvlqfvqaLssrkasellqavalrLla 62
+++l+++ll +L+ L +++ +++ +v fv +Lss+++ + q+ +lr+ +
NP_189404.2 1506 EESLQSCLLCHLGGLMRIFsgsrmnKLFDDVSCFVVSLSSDQTYSCDQKSSLRVSC 1561
45678888888888888877777777777777777777777666666666666655 PP
Or compare NP_189404.2 to CDD or PaperBLAST