Family Search for PF06851 (DUF1247)

PF06851 hits 2 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

AC34_NPVAC / P21287 Protein Ac34 from Autographa californica nuclear polyhedrosis virus (AcMNPV) (see 2 papers)
Aligns to 65:213 / 215 (69.3%), covers 100.0% of PF06851, 355.6 bits

• function: Plays a role in the translocation of the P40 subunit of host Arp2/3 to the nucleus. The robust nuclear accumulation of Arp2/3 induces nuclear actin polymerization to assist in virus replication. Mechanistically, subverts the host CRM1-dependent nuclear export pathway leading to Arp2/3 acumulation in the host nucleus.
  subunit: Interacts with host proteins P40, P34 ands P20.

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