Family Search for PF11685 (DUF3281)

PF11685 hits 7 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

L1103_FRATN / A0Q6X4 Bacterial lipoprotein FTN_1103; BLP from Francisella tularensis subsp. novicida (strain U112) (see paper)
Aligns to 10:281 / 282 (96.5%), covers 99.6% of PF11685, 291.7 bits

• function: Stimulates the host immune inflammatory signaling system allowing the host to combat the bacteria. Stimulates mouse interleukin- 6 (Il6) production (PubMed:23584588).
  disruption phenotype: Significantly decreases interleukin-6 (Il6) production in a Tlr2-dependent fashion by C57BL/6 mouse BMDM.

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